Publications by authors named "Lisa M Steininger"
J Heart Lung Transplant
December 2024
Article Synopsis
- Plasma-soluble proteins (sHLA-G and sHLA-E) regulate immune responses by affecting NKG2A immune cells in lung transplant recipients (LTRs).
- Disrupted NKG2A responses in LTRs can lead to severe health issues like high-level human cytomegalovirus (HCMV) replication and chronic lung allograft dysfunction (CLAD), which can be fatal.
- The study found that low levels of sHLA-G are linked to worsening CLAD, while high levels of sHLA-E are tied to increased HCMV episodes, suggesting these proteins could be used as biomarkers for these conditions in LTRs.
