Publications by authors named "Lisa Ledger"

Aim: To develop a Theory of Change (ToC) pathway to facilitate the development of a multi-component intervention package supporting pressure Ulcer (PU) risk identification and management, in partnership with people with Long Term Neurological Conditions (LTNC) who self-manage care and live at home, their informal carers and PAs.

Methods: A participatory approach, with extensive input from those whose lives are the focus of the research, was used throughout the 4 interlinked work packages (WP): Iterative data analysis was undertaken with emerging findings from each WP informing subsequent stages of the study.

Findings: Overall, 74 participants contributed across the 4 WPs, incorporating 31 Service Users (SU), 8 carers, 9 Personal Assistants (PAs) and 26 professional stakeholders.

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Aims: To explore patient perceptions and understanding of their pressure ulcer risk and how information is communicated between a nurse and patient in the home setting.

Design: A pragmatic qualitative research design including community-dwelling patients, who were deemed at risk of developing a pressure ulcer.

Methods: Observation of routine interactions between nurse and patient regarding their pressure ulcer risk and semi-structured interviews with 15 community patients following the nursing interaction.

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Antimicrobial resistance (AMR) in has been previously associated with topoisomerase and ribosomal gene mutations rather than specific resistance-conferring genes. Using whole genome sequencing (WGS) to identify potential new AMR mechanisms for it was found that a 2019 clinical isolate with high MIC (2019-043682) for fluoroquinolones, macrolides, lincosamides, pleuromutilins and tetracyclines had a new core genome multilocus sequencing (cgMLST) type (ST10-like) and 91% sequence similarity to the published genome of PG45. Closely related to PG45, a 1982 isolate (1982-M6152) shared the same cgMLST type (ST17), 97.

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Background: Chronic wounds including pressure ulcers represent a significant burden to patients and healthcare providers. Increasingly patients are required to self-manage their care but patient adherence to prevention strategies is a significant clinical challenge. It is important to increase understanding of the factors affecting patients' ability and willingness to follow pressure ulcer prevention interventions.

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Article Synopsis
  • LAMP is a simple and quick method for detecting pathogens in food, and this study aimed to validate it against the FDA's reference method in dry dog food.
  • Fourteen collaborators from seven labs in the U.S. and Canada tested blind-coded dog food samples, comparing results from both the LAMP and the BAM methods.
  • The study found no significant differences in detection rates between the two methods, suggesting that LAMP is a reliable alternative for routine screening in animal food.
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