Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis.

Murine models of coxsackievirus B3 (CVB3)-induced myocarditis well represent the different outcomes of this inflammatory heart disease. Previously, we found that CVB3-infected A.BY/SnJ mice, susceptible for severe acute and chronic myocarditis, have lower natural killer (NK) cell levels than C57BL/6 mice, with mild acute myocarditis.

Long-term functional and echocardiographic assessment after penetrating cardiac injury: 5-year follow-up results.

Background: There is almost no data describing the long-term functional outcome of patients after penetrating cardiac injury.

Methods: A retrospective study at a Level I trauma center from 2000 to 2009.

Results: Sixty-three patients had penetrating cardiac injuries from 28 stabbings and 35 gunshots.