Publications by authors named "Lisa J Murray-Segal"
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Synopsis of recent research by authors named "Lisa J Murray-Segal"
Lisa J Murray-Segal's research primarily focuses on the impacts of oxidative stress and immune response in the context of islet transplantation, aiming to enhance islet graft function and survival.
Her findings demonstrate that overexpression of antioxidant enzymes, particularly glutathione peroxidase and superoxide dismutase, can protect mouse islets from oxidative injury, suggesting potential therapeutic strategies for improving transplantation outcomes.
Additionally, her studies on the role of CD39 in thromboregulation highlight its critical function in reducing thrombotic risks during transplantation procedures, underscoring the importance of managing inflammation and vascular injury in transplant recipients.