Diet and lifestyle factors interact with MAPK genes to influence survival: the Breast Cancer Health Disparities Study.

Introduction: MAPK genes are activated by a variety of factors related to growth factors, hormones, and environmental stress.

Methods: We evaluated associations between 13 MAPK genes and survival among 1,187 nonHispanic White and 1,155 Hispanic/Native American (NA) women diagnosed with breast cancer. We assessed the influence of diet, lifestyle, and genetic ancestry on these associations.