Publications by authors named "Lisa Gutbrod"
Article Synopsis
- - Monoclonal antibodies targeting the spike protein of SARS-CoV-2, like the REGN-COV cocktail, are useful in treating high-risk patients but can lead to viral mutations in those with compromised immune systems.
- - In a kidney transplant patient with low antibody levels, the virus failed to clear after mAb treatment, and it developed three mutations that allowed it to escape neutralization.
- - The eventual virus clearance occurred after adjusting the patient's immunosuppressive medication, suggesting that reducing immunosuppression may help overcome the viral adaptations caused by mAb treatment.
