Publications by authors named "Lisa Gravens-Muller"
Article Synopsis
- Antimicrobial prophylaxis can help children with vesicoureteral reflux (VUR) reduce urinary tract infection recurrences, but requires long-term daily medication.
- A cost-utility model assessed the economic value of different prophylaxis strategies for children under 6 years old with a first UTI and VUR, measuring costs against quality-adjusted life years (QALYs).
- Prophylaxis for Grade IV VUR is cost-effective at $37,903 per QALY gained, while treating Grades III and IV VUR is more expensive at $302,024 per QALY, and treating all grades of VUR is even costlier at $339,740 per QALY.
Background: Kidney transplant recipients are at increased risk for adverse safety events related to their reduced renal function and many medications.
Methods: We determined the incidence of adverse safety events based on previously defined Agency for Healthcare and Research Quality (AHRQ) International Classification of Diseases-9 (ICD-9) code-derived patient safety indicators (PSI) in the Folic Acid for Vascular Outcome Reduction in Transplant trial participants who had a hospitalization stratified by tertiles of estimated glomerular filtration rate (GFR). We also examined the frequency of Micromedex defined two precautionary drug-drug interactions, and two medications whose use may be contraindicated because of reduced GFR from the Folic Acid for Vascular Outcome Reduction in Transplant trial medication thesaurus at baseline, and annually among 4,110 participants.
Iron deficiency is prevalent in a sample of pregnant women at delivery in Germany.
Eur J Obstet Gynecol Reprod Biol
May 2002
Objective: To determine the prevalence and risk factors of iron deficiency in pregnancy, since iron supplements are not routine in Germany.
Study Design: Soluble transferrin receptor (sTfR), ferritin, hemoglobin (Hb), C-reactive protein (CRP) and leucocyte counts were determined in venous blood samples of 378 women before delivery; 191 of them filled in a questionnaire. Statistical analysis was performed using SPSS 9.