Development of cytomegalovirus-mediated sensorineural hearing loss in a Guinea pig model.

Objective: To develop an animal model for cytomegalovirus (CMV)-induced sensorineural hearing loss.

Design: Guinea pig model.

Setting: University of Utah otolaryngology research labs.

Resorption rate and biocompatibility characteristics of two polyester ventilation tubes in a guinea pig model.

Objectives: Determine the resorption rate and biocompatibility characteristics of 2 polyester ventilation tubes, and to determine whether soap and water exposure accelerates polyester tube degradation.

Study Design And Setting: 50/50 poly (D, L-lactide-co-glycolide; PLGA-50) and poly (L-lactide; PLA) polymers were placed into the tympanic membranes of Hartley pigmented guinea pigs. Integrity of the tubes was determined by weekly otoscopic examination.

Speech understanding by cochlear-implant patients with different left- and right-ear electrode arrays.

Electrode-pitch rankings and monaural and binaural speech perception scores were obtained from two patients fit with a Med El CIS-Link processor and Ineraid electrode array in one ear and a Clarion processor and Hi-Focus electrode array in the other ear. The results of the electrode-ranking task indicated that current from the Hi-Focus electrodes extended more apically than current from the Ineraid array, i.e.