Publications by authors named "Lisa D Wauters"
Script training is a speech-language intervention designed to promote fluent connected speech via repeated rehearsal of functional content. This type of treatment has proven beneficial for individuals with aphasia and apraxia of speech caused by stroke and, more recently, for individuals with primary progressive aphasia (PPA). In the largest study to-date evaluating the efficacy of script training in individuals with nonfluent/agrammatic primary progressive aphasia (nfvPPA; Henry et al.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates whether primary progressive apraxia of speech (PPAOS) and progressive agrammatic aphasia (PAA) are distinct conditions or part of a larger non-fluent aphasia spectrum.
- Using a group of 98 patients, the research examined speech and language characteristics, alongside disease severity, to identify meaningful clinical subgroups and potential shared pathologies.
- Findings indicated that most participants fit known clinical categories, but the overall data showed low clustering tendencies, suggesting that these speech disorders may not form clear, distinct syndromic entities.
Primary progressive aphasia (PPA) and primary progressive apraxia of speech (PPAOS) are neurodegenerative syndromes characterized by progressive decline in language or speech. There is a growing number of studies investigating speech-language interventions for PPA/PPAOS. An updated systematic evaluation of the treatment evidence is warranted to inform best clinical practice and guide future treatment research.
View Article and Find Full Text PDFArticle Synopsis
- - The non-fluent/agrammatic variant of primary progressive aphasia (nfvPPA) is characterized by symptoms like apraxia of speech and expressive agrammatism, leading to varying speech-language difficulties among patients over time.
- - There is ongoing debate about whether to classify subtypes of nfvPPA based on symptom presence, including 'primary progressive apraxia of speech' and 'progressive agrammatic aphasia', but overlapping features challenge clear distinctions.
- - In a study involving 104 patients, researchers linked specific brain atrophy to varying speech-language symptoms, identifying that the neural correlates for both apraxia of speech and expressive agrammatism are located in the left posterior inferior frontal
Semantic variant primary progressive aphasia (svPPA) is a neurodegenerative disorder characterized by a loss of semantic knowledge in the context of anterior temporal lobe atrophy (left > right). Core features of svPPA include anomia and single-word comprehension impairment. Despite growing evidence supporting treatment for anomia in svPPA, there is a paucity of research investigating neural mechanisms supporting treatment-induced gains and generalization to untrained items.
View Article and Find Full Text PDF