Publications by authors named "Lisa Cooper"

Background: As a powerful, objective marker of frailty, 4-m gait speed (4MGS) can predict morbidity and mortality in various populations including cardiac surgery and oncology patients. Its role in thoracic surgery is understudied. This study aimed to evaluate associations between preoperative 4MGS and outcomes after pulmonary resection.

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Background: Frailty is a state of high vulnerability to adverse health outcomes. It is an important factor influencing the prognosis of older, critically ill patients. Several methods to assess frailty were evaluated in the critical care setting.

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This state-of-the-art review examines disparities in the diagnosis, management, and outcomes of cardiac arrhythmias globally. These arrhythmias include atrial fibrillation, ventricular tachyarrhythmias underlying sudden cardiac death, and bradyarrhythmias associated with sinus node and atrioventricular node disease. Arrhythmias in low- and middle-income countries often result in higher mortality rates due to complex and poorly documented risk factors, lack of clinical expertise among health care personnel, lack of sufficient infrastructure, and challenges in access to care.

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Background And Objectives: Individuals with low income or from minoritized racial or ethnic groups experience a high burden of hypertension and other chronic conditions (eg, diabetes, chronic kidney disease, and mental health conditions) and often lack access to specialist care when compared to their more socially advantaged counterparts. We used a mixed-methods approach to describe the deployment of a Remote Collaborative Specialist Panel intervention aimed at the comprehensive and coordinated management of patients with hypertension and comorbid conditions to address health disparities.

Methods: Participants of the collaborative care/stepped care arm of the Reducing Inequities in Care of Hypertension: Lifestyle Improvement for Everyone (RICH LIFE) Project, a cluster-randomized trial comparing the effectiveness of enhanced standard of care to a multilevel intervention (collaborative care/stepped care) for improving blood pressure control and reducing disparities, were included.

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Article Synopsis
  • African Americans face higher cardiovascular disease mortality compared to White adults due to elevated prevalence of cardiovascular risk factors, but a mobile health intervention has shown promise in improving cardiovascular health in this group.
  • A cluster randomized controlled trial in Minnesota involving participants from 16 churches assessed the effectiveness of this culturally tailored mHealth intervention against a delayed control group, focusing on individuals with obesity and other related conditions.
  • Results indicated that participants in the intervention group experienced a significant increase in their LS7 cardiovascular health scores, particularly among those with obesity and multiple risk factors, highlighting the intervention's potential impact on enhancing cardiovascular health for African Americans.
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Objectives: To identify COVID-19 infectious disease models that accounted for social determinants of health (SDH).

Methods: We searched MEDLINE, EMBASE, Cochrane Library, medRxiv, and the Web of Science from December 2019 to August 2020. We included mathematical modelling studies focused on humans investigating COVID-19 impact and including at least one SDH.

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  • Bats are increasingly recognized as valuable models for aging research due to their long lifespan, living over 20 to 40 years in the wild or captivity.
  • Their unique biological traits, such as resistance to viral infections and efficient DNA repair mechanisms, offer insights that could enhance healthy aging in humans.
  • The review discusses eight specific areas where bat research can inform our understanding of aging, including genetics, immunity, neurobiology, and even aspects related to menopause, making bats potentially more relevant to human aging studies than traditional lab animals like rodents.
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Background: Infectious disease (ID) models have been the backbone of policy decisions during the COVID-19 pandemic. However, models often overlook variation in disease risk, health burden, and policy impact across social groups. Nonetheless, social determinants are becoming increasingly recognized as fundamental to the success of control strategies overall and to the mitigation of disparities.

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Background: African-American (AA) women are less likely to achieve ideal cardiovascular (CV) health compared with women of other racial/ethnic subgroups, primarily due to structural and psychosocial barriers. A potential psychosocial construct relevant to ideal CV health is the superwoman schema (SWS).

Purpose: We explored whether the SWS was associated with perceived stress, CV risk factors, and overall CV health among AA women.

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  • Health systems must actively address health equity by transforming their practices in social, economic, and political contexts, particularly in managing health disparities interventions like hypertension care.
  • This qualitative study compares how various organizations, including Federally Qualified Health Centers (FQHCs) and a private health system, implemented and sustained a hypertension disparities intervention through interviews with health care leaders.
  • Key challenges included ensuring proper staffing and securing organizational commitment, with varied sustainability strategies; FQHCs depended on funding while a private practice focused on resource expansion, highlighting the need for supportive policies and further research on organizational factors impacting health disparities.
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Background: Disparities in hypertension control are well documented but underaddressed.

Methods: RICH LIFE (Reducing Inequities in Care of Hypertension: Lifestyle Improvement for Everyone) was a 2-arm, cluster randomized trial comparing the effect on blood pressure (BP) control (systolic BP ≤140 mm Hg, diastolic BP ≤90 mm Hg), patient activation, and disparities in BP control of 2 multilevel interventions, standard of care plus (SCP) and collaborative care/stepped care (CC/SC). SCP included BP measurement standardization, audit and feedback, and equity-leadership training.

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Background: Shared decision-making (SDM) has the potential to improve hypertension care quality and equity. However, research lacks diverse representation and evidence about how race and ethnicity affect SDM. Therefore, this study aims to explore SDM in the context of hypertension management.

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Background: Personal characteristics may be associated with believing misinformation and not believing in best practices to protect oneself from COVID-19.

Objective: To examine the associations of a person's age, race/ethnicity, education, residence, health literacy, medical mistrust level, and sources of health-related information with their COVID-19 health and conspiracy myth beliefs.

Design: We surveyed adults with hypertension in Maryland and Pennsylvania between August 2020 and March 2021.

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In this paper, we introduce an analytic approach for assessing effects of multilevel interventions on disparity in health outcomes and health-related decision outcomes (i.e., a treatment decision made by a healthcare provider).

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  • This study explores the post-operative functional outcomes for severely frail older adults after femur fracture surgery, emphasizing patient- or proxy-reported results rather than just complications and mortality.
  • Involving 37 predominantly female patients with a median age of 85, the study assessed various outcomes including mobility, independence, psychosocial aspects, and pain levels more than a year post-surgery.
  • Findings indicate that despite their frailty, many patients (70%) regained some level of ambulation, with significant variability in functional independence, suggesting that surgical treatment can help improve quality of life for this population.
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Background: African Americans (AAs) face cardiovascular health (CVH) disparities linked to systemic racism. The 2020 police killing of Mr. George Floyd in Minneapolis, Minnesota, alongside the COVID-19 pandemic, exacerbated adverse psychosocial factors affecting CVH outcomes among AAs.

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Introduction: People with serious mental illness experience grave disparities in cardiovascular disease risk factors. To promote scale-up of effective cardiovascular disease risk reduction interventions from clinical trials, it is important to involve end-users in adapting interventions to fit the needs of community-based settings.

Objective: We describe a novel, theory-informed process of garnering community input to adapt IDEAL Goals, an evidence-based intervention for improving cardiovascular disease risk factors in persons with serious mental illness.

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Socio-demographic inequities in health treatment and outcomes are not new. However, the COVID-19 pandemic presented new opportunities to examine and address biases. This article describes a scoping review of 170 papers published prior to the onset of global vaccinations and treatment (December 2021).

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Article Synopsis
  • Hypertension and diabetes are significant risks for conditions like cardiovascular disease and stroke, especially among Black and Hispanic communities and those in poverty.
  • The LINKED-HEARTS Program aims to improve blood pressure control through home monitoring, telehealth, and community support, compared to regular care options.
  • The study involves 428 adults recruited from primary care practices, assessing the effectiveness of this intervention over a year to enhance chronic disease management and reduce health disparities.
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Current management of esophageal carcinoma (EC) involves combining different modalities, offering the opportunity of personalized strategies. This is particularly enticing in the geriatric population, where tailoring treatment modalities remains key to achieve good outcomes in terms of both quality of life and survival. Primary outcomes of our review included (1) evidence on short-term outcomes following esophagectomy, and (2) evidence on long-term outcomes following esophagectomy.

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Objective: Evidence suggests that racial discrimination causes stress among non-Hispanic Black women, and some Black women may cope with exposure to vicarious racial discrimination by engaging in maladaptive eating behaviors.

Methods: We examined eating behaviors among Black women (N = 254) before and after Freddie Gray's death while in police custody. Maladaptive eating behaviors were assessed using the three-factor eating questionnaire.

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