Publications by authors named "Lisa Bryan"
sp. nov., a novel species isolated from an infected prosthetic aortic graft in a human.
Int J Syst Evol Microbiol
December 2023
A novel bacterial strain, GSTT-20 was isolated from an infected, prosthetic endovascular graft explanted from a shepherd in London, United Kingdom. This strain was an aerobic, catalase-positive, oxidase-negative, Gram-stain-negative, motile, curved rod. It grew on blood agar, chocolate agar and MacConkey agar incubated at 37 °C in an aerobic environment after 48 h, appearing as yellow, mucoid colonies.
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- Clinical metagenomics (CMg) could enhance antimicrobial treatment and infection control, especially highlighted by the SARS-CoV-2 pandemic, which increased risks of infections from drug-resistant pathogens in ICUs.
- A study involving 43 respiratory samples from intubated COVID-19 patients showed that an 8-hour CMg workflow was 92% sensitive and 82% specific in identifying bacteria, while also detecting antibiotic-resistant genes that could change treatment plans.
- CMg testing allows for timely pathogen detection and resistance predictions, suggesting it could transform infection management in ICUs and warrants further clinical evaluation for broader implementation.
Research funding from public and private sources has reached an all-time low. Economic conditions, sequestration, and a trend of low award success rates have created an imbalance between the supply of highly qualified research investigators and the availability of critically necessary research dollars. This grim environment continues to hinder the success of established investigators and deter potential investigators from joining the research workforce.
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