Publications by authors named "Lisa Angela Huang"
Article Synopsis
- PDAC, or pancreatic ductal adenocarcinoma, faces treatment challenges due to its immune-resistant environment, particularly influenced by tumor-associated nonmyelinating Schwann cells (TASc).
- Research found that higher levels of TASc are linked to immune suppression and poorer patient outcomes, and removing these cells can actually boost tumor growth.
- Additionally, a specific long noncoding RNA related to TASc, activated by interleukin-6 from tumor cells, plays a critical role in altering enzymatic processes that aid PDAC progression, making TASc a potential target for improving immunotherapy effectiveness.
