Perceptions Toward Naloxone Among Patients With Cancer Receiving Opioids.

Context: Naloxone nasal spray is recommended for patients with risk factors for opioid overdose. However, cancer patients' perceptions and beliefs regarding naloxone prescriptions and their self-perceived risks for overdose are understudied.

Objective: To determine the proportion of cancer patients at risk for overdose who perceived naloxone as beneficial.

Degree of twisting and duration of symptoms are prognostic factors of testis salvage during episodes of testicular torsion.

Background: Testicular torsion is surgical emergency. Prompt diagnosis and treatment of testicular torsion is essential for testicular viability. At surgical exploration, the spermatic cord is seen twisted a variable number of times around its longitudinal axis.

Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions.

Cell-cell interactions through adhesion molecules play key roles in the development of the nervous system. Synaptic cell adhesion molecules (SynCAMs) comprise a group of four immunoglobulin (Ig) superfamily members that mediate adhesion and are prominently expressed in the brain. Although SynCAMs have been implicated in the differentiation of neurons, there has been no comprehensive analysis of their expression patterns.

Pituitary volumes in pediatric maltreatment-related posttraumatic stress disorder.

Background: Previous findings suggest that corticotrophin-releasing hormone (CRH) is elevated in adults with posttraumatic stress disorder (PTSD), maltreated children, and children with maltreatment-related PTSD.

Methods: Magnetic resonance imaging was used to measure pituitary volumes in 61 medication-naïve maltreated subjects with PTSD (31 male and 30 female subjects) and 121 nontraumatized healthy comparison subjects (62 male and 59 female subjects).

Results: Overall, no differences were seen between PTSD and control subjects in pituitary volumes.

Biologic findings of post-traumatic stress disorder and child maltreatment.

Child maltreatment is a serious problem in US society, affecting approximately three million children. Children and adolescents exposed to child abuse and neglect experience high rates of post-traumatic stress disorder (PTSD). In addition, they are at risk for comorbid mental illness.