Publications by authors named "Lirue Zhou"
Nat Nanotechnol
September 2023
Article Synopsis
- * High cholesterol levels result in a protein corona that is enriched with apolipoproteins and has fewer complement proteins, leading to stronger inflammatory responses in macrophages and increased uptake in liver cells.
- * The study's in vivo results show that NPs are more effectively targeted to organs like the liver and brain in mice with hypercholesterolemia, highlighting how the metabolome can influence the efficacy and safety of nanomedicines and suggesting a potential for personalized treatment approaches.
