Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment.

Background: The detection and early identification of people living with HIV/AIDS (PLWH) and their rapid engagement in antiretroviral treatment are indispensable for fighting HIV transmission. This study aimed to elicit preferences regarding HIV testing among community residents to identify a model of community-based HIV testing services that would appeal to this population.

Methods: A discrete-choice experiment (DCE) was conducted in the communities of Yunnan Province, China.

Health utility measurement for people living with HIV/AIDS under combined antiretroviral therapy: A comparison of EQ-5D-5L and SF-6D.

We compared the discriminative validity, agreement and sensitivity of EQ-5D-5L and SF-6D utility scores in people living with HIV/AIDS (PLWHIV). We conducted a cross-sectional survey among PLWHIV aged more than 18 years old in 9 municipalities in Yunnan Province, China. A convenience sample was enrolled.

MiR-222-3p promotes the proliferation, migration and invasion of papillary thyroid carcinoma cells through targeting SLC4A4.

Objective: An increasing number of studies indicate that miR-222-3p is upregulated in various cancers and can regulate tumor progression. This study aimed to explore the regulatory mechanism of miR-222-3p in papillary thyroid carcinoma (PTC).

Methods: TCGA database was used to dig differentially expressed miRNAs and mRNAs in PTC tissue.

The role of personality, social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS.

Background: HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent. The additional of so called fourth 90% that included the improved health-related quality of life (HRQoL) for people living with HIV (PLWHIV) required solutions beyond antiretroviral therapy and viral load suppression. This study will explore the role of personality, social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.

[Change trend of HIV/AIDS related risk factors and influencing factors among men who have sex with men in Yunnan, 2010-2013].

Objective: To understand the change trend of the awareness rate of HIV/AIDS related knowledge, risk behaviors among men who have sex with men (MSM) in Yunnan and the factors influencing their condom use, and evaluate the effect of comprehensive intervention.

Methods: The data about the MSM's demographic information, HIV/AIDS related knowledge awareness, and sex behavior, condom use, drug use and intervention receiving were obtained from AIDS sentinel surveillance among MSM in Yunnan province during 2010-2013 to conduct change trend and influencing factor analysis.

Results: A total of 9 073 MSM were surveyed.

[Distribution of HIV-1 subtypes among different populations in Dehong prefecture, Yunnan province, in 2011].

Objective: To investigate the distribution of HIV-1 subtypes in Dehong prefecture, Yunnan province, in 2011.

Methods: 300 HIV-1 positive plasma samples were collected from Jan. 2011 to May 2011 in Dehong prefecture.

Genetic diversity and drug resistance among newly diagnosed and antiretroviral treatment-naive HIV-infected individuals in western Yunnan: a hot area of viral recombination in China.

Background: The emergence of an HIV-1 epidemic in China was first recognized in Dehong, western Yunnan. Due to its geographic location, Dehong contributed greatly in bridging HIV-1 epidemics in Southeast Asia and China through drug trafficking and injection drug use; and also extensively to the HIV genetic diversity in Yunnan and China. We attempt to monitor HIV-1 in this area by studying the HIV-1 genetic distribution and transmitted drug resistance (TDR) in various at-risk populations.

[A comprehensive surveillance on HIV among 1,237 men who have sex with men in thirteen cities of Yunnan].

Objective: To understand the knowledge, risk behaviors and HIV prevalence in men who have sex with men (MSM) in thirteen cities.

Methods: Target samples were chosen using the snowball-rolling method, with transverse KABP and HIV-antibody testing developed for those MSM in thirteen cities of Yunnan.

Results: A total of 1237 valid questionnaires and 1129 blood samples were collected.

[Incidence and risk factors on HIV infection among injection drug users in Dehong prefecture area of Yunnan province].

Objective: To determine the incidence and risk factors on HIV infection among injection drug users (IDU) in Dehong prefecture area of Yunnan province.

Methods: An epidemiological cohort of HIV-negative IDU had been developed and followed since October, 2004. HIV new infections and related behaviors had been investigated every six months.

The HIV epidemic in Yunnan Province, China, 1989-2007.

Objective: To investigate the characteristics and trends in the HIV epidemic in Yunnan province, China, between 1989 and 2007.

Methods: Statistical analysis of serological data from voluntary testing and counseling sites, medical case reports, mass screenings, sentinel surveillance, and other sources.

Results: By 2007, a cumulative total of 57,325 cases of HIV infection were reported in Yunnan, and unsafe drug injection practices and unsafe sexual behaviors were identified as the dominant modes of transmission.

[Analysis for epidemic trend of acquired immunodeficiency syndrome in Yunnan Province of China].

Objective: To understand epidemiologic characteristics and changes in epidemic trend of human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) in different areas and populations of Yunnan Province.

Methods: Seroepidemiological studies were conducted in injection drug users (IDUs), women sex workers, whoring goers, patients with sexually transmitted disease (STD), patients with tuberculosis, pregnant women and blood donors with sentinel surveillance, ad hoc investigations, regular case-finding and data collection during 1989 to 2003 in Yunnan Province.

Results: Relatively high prevalence of HIV/AIDS was firstly found in IDUs from border areas of the province in 1989.