Nicotinamide Mononucleotide Improves Spermatogenic Disorders in Aluminum-Exposed Rats by Modulating the Glycolytic Pathway.

This study aimed to investigate the protective effect of nicotinamide mononucleotide (NMN) on testicular spermatogenesis in aluminum chloride (AlCl)-exposed rats and to elucidate the potential underlying mechanism. The results indicated that AlCl-induced testicular damage, leading to reduced sperm quality, increased apoptosis, decreased cell proliferation, and impaired Sertoli cell function in rats. Additionally, glycolytic metabolism was observed to be hindered.

[Correlation Analysis between and Single Nucleotide Polymorphism and the Risk of G6PD Deficiency].

Objective: To investigate the possible association between , polymorphism and G6PD deficiency in the population of Guangxi by the methods of case-control study. Meanwhile to investigate the mutation frequency of these two gene loci in population of Guangxi.

Methods: The activity levels of G6PD and , polymorphism were detected in 417 patients with G6PD deficiency and 295 healthy controls.

Simultaneous detection of mutations using SNPscan in a multiethnic minority area of Southwestern China.

Baise, a multiethnic inhabited area of southwestern China, is a historical malaria-endemic area with a high prevalence of deficiency. However, few studies of deficiency have been conducted in this region. Therefore, we performed a genetic analysis of deficiency in the Baise population from January 2020 to June 2021.

[Study of ice VII structure influenced by high pressure using Raman spectrum].

Raman spectra of ice VII phase were obtained at room temperature when the pressure was from 2.5 to 23 GPa. The experimental results indicate that the oxygen atoms distance do-o of ice decreased with pressure increasing,which results in that hydrogen bond is shortened, O--H bond is lengthened,force constant is reduced, and Raman spectra are red shifted.