Effect of different anesthetic modalities on postoperative delirium in elderly hip fractures: A meta-analysis.

Background: Previous findings on the effect of general versus spinal anesthesia on postoperative delirium in elderly people with hip fractures are somewhat controversial. This article included the latest randomized controlled study for meta-analysis to evaluate the effect of general anesthesia (GA) and spinal anesthesia (SA) on delirium after hip fracture surgery in the elderly, so as to guide the clinical.

Methods: Cochrane Library, PubMed, Web Of Science, and Embase were searched from inception up to January 16, 2024.

The effects of modified Guizhi plus Gegen decoction combined with the blade needle therapy on TCM syndromes, cervical curvature and levels of inflammatory factors in patients with cervical spondylotic radiculopathy.

Objective: To explore the effect of modified Guizhi plus Gegen decoction combined with the blade needle therapy on traditional Chinese medicine (TCM) syndromes, cervical curvature, and inflammatory factor levels in patients with cervical spondylotic radiculopathy.

Methods: In this retrospective study, 114 patients with cervical spondylotic radiculopathy who visited Pain Clinic, Hangzhou Fuyang Hospital of TCM Orthopedics and Traumatology from January 2020 to December 2022 were selected as the study subjects. According to different treatment methods, these patients were divided into an observation group (n=57, treated with blade needle therapy) and a control group (n=57, treated with modified Guizhi plus Gegen decoction combined with the blade needle therapy).

Evaluation of the efficacy and safety of day surgery for cervical disc herniation treated with low temperature plasma radiofrequency ablation.

Purpose: The purpose of this study was to evaluate and compare the clinical efficacy of patients with cervical disc herniation (CDH) treated by low-temperature plasma radiofrequency ablation (LTP-RFA) as day surgery with traditional inpatients.

Methods: According to the selection criteria, single-segment mild to moderate CDH patients who received LTP-RFA from January 2020 to December 2021 were divided into day surgery procedure (DSP) group and a traditional inpatient procedure (TIP) group. The visual analogue score (VAS) and modified Japanese Orthopedic Association score (mJOA) of neurological function of patients in the two groups were recorded at the time of preoperative, and one day, three months, six months after surgery and the last follow-up respectively.

Analysis of risk factors for postoperative delirium in middle-aged and elderly fracture patients in the perioperative period.

To investigate the incidence rate and risk factors of postoperative delirium in middle-aged and elderly patients with fracture. A total of 648 middle-aged and elderly fracture patients who underwent surgical treatment in our hospital from January 2018 to December 2020 were included in the study, aged 50-103 years, mean 70.10 ± 11.

Research progress on long non-coding RNAs for spinal cord injury.

Spinal cord injury is a complex central nervous system disease with an unsatisfactory prognosis, often accompanied by multiple pathological processes. However, the underlying mechanisms of action of this disease are unclear, and there are no suitable targeted therapeutic options. Long non-coding RNA mediates a variety of neurological diseases and regulates various biological processes, including apoptosis and autophagy, inflammatory response, microenvironment, and oxidative stress.

Magnetodielectric Properties of Ordered Microstructured Polydimethylsiloxane-Based Magnetorheological Elastomer with FeO@rGO Nanoparticles.

Magnetodielectric properties of prepared ordered microstructured polydimethylsiloxane-based magnetorheological elastomer with the FeO@rGO (FeO@rGO/PDMS-MRE) were investigated to expand the application of magnetorheological elastomer (MRE) in magnetic sensing fields by improving the magnetodielectric effect. Five types of FeO@rGO electromagnetic biphasic composite particles were synthesized by the solvothermal method, and their characterization and magnetic properties were also tested. Microstructurally ordered FeO@rGO/PDMS-MRE samples with different FeO@rGO concentrations were obtained through the magnetic field orientation technique, an experimental platform for magnetodielectric properties was built, and the relative permittivity of the samples was tested under magnetic flux density from 0 to 500 mT.

Antimicrobial peptide CC34 attenuates intestinal inflammation via downregulation of the NF-κB signaling pathway.

The investigational drug CC34 is a cation peptide with multiple bioactivities. Here, we studied the anti-inflammatory effects of CC34 in lipopolysaccharide (LPS)-treated mouse monocyte-macrophage cells (RAW264.7) and in mice with LPS-induced intestinal inflammation.

USF2 reduces BMP3 expression via transcriptional activation of miR-34a, thus promoting osteogenic differentiation of BMSCs.

Introduction: Osteoporosis is the most susceptible disease for people over 60. The main cause of osteoporosis is the decreased osteogenic differentiation of mesenchymal stem cells (MSCs). Here we showed that upstream stimulatory factor 2 (USF2)/microRNA-34a (miR-34a)/bone morphogenetic protein 3 (BMP3) axis regulated osteogenic differentiation of BMSCs.

Logistic regression analysis on risk factors of augmented vertebra recompression after percutaneous vertebral augmentation.

Objective: To explore the high-risk factors of augmented vertebra recompression after percutaneous vertebral augmentation (PVA) in the treatment of osteoporotic vertebral compression fracture (OVCF) and analyze the correlation between these factors and augmented vertebra recompression after PVA.

Methods: A retrospective analysis was conducted on 353 patients who received PVA for a single-segment osteoporotic vertebral compression fracture from January 2017 to December 2018 in our department according to the inclusion criteria. All cases meeting the inclusion and exclusion criteria were divided into two groups: 82 patients in the recompression group and 175 patients in the non-compression group.

Measurements of cardiac efficiency and internal work of the left ventricle via reconstructed impedance cardiography.

. The aim of this study was to investigate methods for measuring the cardiac efficiency (CE) and internal work (IW) of the left ventricle via reconstructed impedance cardiography (RICG).On the basis of the physiological context and Bernoulli's equation in physics, methods of measuring the CE and IW were proposed.

Artesunate promotes osteoblast differentiation through miR-34a/DKK1 axis.

Background: Osteoporosis is characterised by impairment of microarchitecture and bone mass. Therapeutic strategy promoting osteoblast differentiation is considered as a promising direction for the treatment of osteoporosis. Artesunate (ART) is related to osteoporosis, but the relationship between ART and osteogenic differentiation is still unknown.

Is the Thoracolumbar AOSpine Injury Score Superior to the Thoracolumbar Injury Classification and Severity Score for Guiding the Treatment Strategy of Thoracolumbar Spine Injuries?

Objective: To determine whether Thoracolumbar Injury Classification and Severity Score (TLICS) and the Thoracolumbar AOSpine Injury Score (TL AOSIS) have any superiority to each other in terms of the reliability of their recommendations for guiding the treatment strategy of thoracolumbar spine injuries.

Methods: A total of 110 consecutive patients with thoracolumbar injuries hospitalized from January to September 2019 were analyzed retrospectively. The TLICS and the TL AOSIS systems were compared based on patients' therapeutic decisions suggested by each system.

Predictive formula of cervical lordosis in asymptomatic young population.

Background: Not a large number of previous studies have reported the normal sagittal balance of the cervical spine and physiological cervical lordosis (CL) has not been clearly defined yet.

Methods: This was a prospective radiological analysis of asymptomatic subjects. The following cervical sagittal parameters were measured: CL, thoracic inlet angle (TIA), T1 slope (T1S), neck tilt (NT), and C2-7 sagittal vertical axis (C2-7 SVA).

Importance evaluation of spectral lines in Laser-induced breakdown spectroscopy for classification of pathogenic bacteria.

The correct classification of pathogenic bacteria is significant for clinical diagnosis and treatment. Compared with the use of whole spectral data, using feature lines as the inputs of the classification model can improve the correct classification rate (CCR) and reduce the analyzing time. In order to select feature lines, we need to investigate the contribution to the CCR of each spectral line.

Testing and Modeling the Responses of Hybrid III Crash-Dummy Lower Extremity under High-speed Vertical Loading.

Anthropometric test devices (ATDs), such as the Hybrid III crash-test dummy, have been used to simulate lowerextremity responses to military personnel subjected to loading conditions from anti-vehicular (AV) landmine blasts. Numerical simulations [e.g.

Investigation of pediatric neck response and muscle activation in low-speed frontal impacts.

Pediatric necks present different responses and injury patterns compared with those of adults in motor vehicle crashes (MVCs). To evaluate the effect of different muscle modeling methodologies, three muscle models were developed and simulated under low-speed frontal impact conditions with an average peak acceleration of 3g's. The muscle activation curve for the curve-guided model, the muscle segment was curved using guiding nodes, was further optimized based on experimental data.

Blast effect on the lower extremities and its mitigation: a computational study.

A series of computational studies were performed to investigate the response of the lower extremities of mounted soldiers under landmine detonation. A numerical human body model newly developed at Wayne State University was used to simulate two types of experimental studies and the model predictions were validated against test data in terms of the tibia axial force as well as bone fracture pattern. Based on the validated model, the minimum axial force causing tibia facture was found.

Development and validation of a 10-year-old child ligamentous cervical spine finite element model.

Although a number of finite element (FE) adult cervical spine models have been developed to understand the injury mechanisms of the neck in automotive related crash scenarios, there have been fewer efforts to develop a child neck model. In this study, a 10-year-old ligamentous cervical spine FE model was developed for application in the improvement of pediatric safety related to motor vehicle crashes. The model geometry was obtained from medical scans and meshed using a multi-block approach.

[Effective analysis of continous perfusion with Dandshen and heparin for treatment of femoral head necrosis].

Objective: To investigate the effect of continous perfusion with Danshen and heparin for treatment of femoral head necrosis.

Methods: From April 2004 to June 2007,42 patients of femoral head necrosis were treated by contious perfusing with Dandshen and heparin, included 24 males and 18 females with an average age of 39.2 years ranging from 13 to 61 years.

[Electrooptical properties of nanoscale and bulk SrAl2O4: Eu, Dy].

Nanoscale and bulk SrAl2O4 : Eu2+, Dy3+ were prepared respectively by auto-combustion of citrate gelatin and high temperature solid state method. The crystalline structure was examined by X-ray diffraction (XRD). The current-voltage characteristic was measured with a Keithley source meter 2 410.

[Clinical control study in treating degenerative lumbar instability with single or double carbon fiber cages].

Objective: To compare the clinical and radiologic effect in treating degenerative lumbar instability with single or double carbon fiber cages.

Methods: From November 2005 to October 2006, 97 patients of degenerative lumbar instability were followed up more than two years. All cases underwent pedicle screw fixation.

[Effect of static magnetic field on deep wound healing of SD rats].

Objective: To investigate the effect of static magnetic field on deep wound healing of SD rats and VEGF during the wound healing and different strength static magnetic field on deep wound healing of SD rats.

Methods: Divided forty-eight SD rats into three groups: 0.16 T magnetic disk treatment (0.