Publications by authors named "Liqi Duan"
Article Synopsis
- Dendritic cells (DCs) are essential for regulating immune responses in tumors, especially in clear-cell renal-cell carcinoma (ccRCC), but current research has gaps in understanding their role in immune activation.
- The study identified key genes related to activated DCs using RNA-seq data and developed a prognostic model that includes five specific genes, validated using several external data sets.
- This model not only predicts patient outcomes in advanced ccRCC but also shows associations with tumor progression and how patients might respond to therapies like the BET inhibitor JQ1.
This study aims to investigate the effect of Xixin Decoction on the T helper 17 cell(Th17)/regulatory T cell(Treg) ba-lance of intestinal mucosa and the expression of related transcription factors in the senescence-accelerated mouse-prone 8(SAMP8) model. Fifty 14-week male mice of SAMP8 were randomized by the random number table method into model group, probiotics group, and high-, medium-, and low-dose Xixin Decoction groups, with 10 mice in each group. Ten 14-week male mice of senescence-acce-lerated mouse-resistant 1(SAMR1) served as control group.
View Article and Find Full Text PDFThis study aimed to explore the possible effect of Xixin Decoction(XXD) on the learning and memory ability of Alzheimer's disease(AD) model senescence-accelerated mouse-prone 8(SAMP8) and the related mechanism in enhancing neuroprotective effect and reducing neuroinflammation. Forty SAMP8 were randomly divided into a model group(10 mL·kg~(-1)·d~(-1)), a probiotics group(0.39 g·kg~(-1)·d~(-1)), a high-dose group of XXD granules(H-XXD, 5.
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