An open source isolated data acquisition with trigger pulse generation for ion mobility spectrometry.

Ion mobility spectrometers (IMS) are used in a wide variety of applications, including trace gas detection in safety and security applications, but also in more analytical applications, e.g., in medicine or food quality monitoring.

Seventy-five years of impactful environmental and occupational health research at the Nelson Institute of Environmental Medicine at New York University.

Founded in 1947 as the Institute of Industrial Medicine, the Nelson Institute and Department of Environmental Medicine at New York University (NYU) Grossman School of Medicine (NYUGSOM) was supported by a National Institute of Environmental Health Science (NIEHS) Center Grant for over 56 years. Nelson Institute researchers generated 75 years of impactful research in environmental and occupational health, radiation effects, toxicology, and cancer. Environmental health research is continuing at NYUGSOM in its departments of medicine and population health.

A hyper-fast gas chromatograph coupled to an ion mobility spectrometer with high repetition rate and flow-optimized ion source to resolve the short chromatographic peaks.

By combining the high selectivity of a gas chromatograph (GC) with the high sensitivity and decent selectivity of an ion mobility spectrometer (IMS), GC-IMS have become increasingly popular in many applications. However, most GC suffer from long analysis times. In contrast, an hyper-fast GC allows for extremely fast analysis in the tens of seconds while reaching comparably high resolution.

High-Resolution Drift Tube Ion Mobility Spectrometer with Ultra-Fast Polarity Switching.

Besides safety and security applications, ion mobility spectrometry (IMS) is increasingly used in other fields such as medicine, environmental monitoring and food quality analysis. However, some applications require gas chromatographic separation before analysis by IMS. Furthermore, different compounds in the sample may form positive or negative ions during ionization and therefore simultaneous detection of both ion polarities is highly beneficial to avoid two chromatographic runs of the same sample.

Pursuing drug laboratories: Analysis of drug precursors with High Kinetic Energy Ion Mobility Spectrometry.

High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) is a technique for rapid and reliable detection of trace compounds down to ppb-levels within one second. Compared to classical IMS operating at ambient pressure and providing the ion mobility at low electric fields, HiKE-IMS can also provide the analyte-specific field dependence of the ion mobility and a fragmentation pattern at high reduced electric field strengths. The additional information about the analyte obtained by varying the reduced electric field strength can contribute to reliable detection.

Influence of ionization volume and sample gas flow rate on separation power in gas chromatography-ion mobility spectrometry.

In this work, the influence of the sample gas flow rate and the ionization region volume of an ion mobility spectrometer (IMS) used as a detector in gas chromatography (GC) on GC-IMS peak shape has been investigated. Therefore, a drift tube IMS with a field-switching ion shutter, a defined ionization region volume and an ultra-violet radiation source was used. To identify the influence of the sample gas flow rate entering the ionization region (equals the GC carrier gas flow rate if no further make-up gas is used) and the ionization region volume on peak broadening and signal intensity, different sample volumes as they would elute from a GC were tested at a variety of sample gas flow rates at a given ionization region volume.

Detection of Triacetone Triperoxide by High Kinetic Energy Ion Mobility Spectrometry.

High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) is a versatile technique for the detection of gaseous target molecules that is particularly useful in complex chemical environments, while the instrumental effort is low. Operating HiKE-IMS at reduced pressures from 10 to 60 mbar results in fewer ion-neutral collisions than at ambient pressure, reducing chemical cross-sensitivities and eliminating the need for a preceding separation dimension, e.g.

Emerging Adults' Perspectives on Consensually Nonmonogamous Parenting.

Consensual nonmonogamy (CNM) is increasingly recognized as a relevant aspect of family and relational diversity in the USA, but CNM-parenting is still perceived as a taboo topic. Pioneering research has only started to emerge and reveals persisting notions of regulation, discrimination, and stigmatization of CNM-parents. CNM-stigmatization is less prevalent among emerging adults, but it is unclear whether young adults' increasing acceptance of CNM relationships extends to their views on parenting.

Using an Online-Based Mindfulness Intervention to Reduce Test Anxiety in Physics Students.

Using an 8-week mindfulness intervention, we investigated the mechanisms of mindfulness to address test anxiety in introductory physics II. Our goal was to explore the effectiveness of using an 8-week online mindfulness intervention to address student test anxiety. We used self-report measures to assess participants on mindfulness, emotional regulation, attentional regulation, and physics quiz scores at three-time points-time 1 (pre), time 2 (mid), and time 3.

Orientation order of a nonpolar molecular fluid compressed into a nanosmall space.

The ordering structures of non-polar carbon tetrachloride liquid compressed to nano-scales between parallel substrates is studied in this work. The theoretical considerations show that the potential well formed by the confined parallel substrates induces orientational ordering of non-polar molecules. Through molecular dynamic (MD) simulations, the relations between various ordered structures of a non-polar liquid (carbon tetrachloride) and the confined gap size are demonstrated.

Learning on OnlyFans: User Perspectives on Knowledge and Skills Acquired on the Platform.

OnlyFans is a digital patronage platform on which over two million content creators produce sexually explicit content for more than 130 million users. Increased Internet access and innovative technologies that enhance sexuality via connections and knowledge are changing the ways people navigate their sexual lives. OnlyFans is unique due to its position between digital sex work and social media and its high degree of cultural assimilation.

Easy to assemble dielectric barrier discharge plasma ionization source based on printed circuit boards.

Here, we present a new and an easy to assemble dielectric barrier discharge plasma ionization source based on printed circuit boards with two parallel isolated electrodes for generating a plasma inside an inert fused silica capillary. For demonstration, this plasma source is coupled to an ion mobility spectrometer. With two different sample gas feeds the analytes can either pass through the plasma or bypass the plasma before entering the reaction region of the ion mobility spectrometer, allowing for different ionization pathways, e.

The Right Ventricle: From Embryologic Development to RV Failure.

Purpose Of Review: The right ventricle (RV) and left ventricle (LV) have different developmental origins, which likely plays a role in their chamber-specific response to physiological and pathological stress. RV dysfunction is encountered frequently in patients with congenital heart disease (CHD) and right heart abnormalities emerge from different causes than increased afterload alone as is observed in RV dysfunction due to pulmonary hypertension (PH). In this review, we describe the developmental, structural, and functional differences between ventricles while highlighting emerging therapies for RV dysfunction.

College Student Experiences Regarding the Impact of the COVID-19 Pandemic on Their Sexual Lives.

The COVID 19 pandemic has impacted sexual health in a variety of ways. The purpose of this research was to examine the ways in which college students (attending a university providing primarily online curriculum during fall 2020 and spring 2021 semesters) perceive the pandemic influencing their sexual health and lives. Participants were undergraduate students ( = 66) at a mid-sized Western university recruited during the beginning of the spring 2021 semester.

World Trade Center dust induces nasal and neurological tissue injury while propagating reduced olfaction capabilities and increased anxiety behaviors.

Previous and in vivo World Trade Center particulate matter (WTC) exposure studies have provided evidence of exposure-driven oxidative/nitrative stress and inflammation on respiratory tract and aortic tissues. What remains to be fully understood are secondary organ impacts due to WTC exposure. This study was designed to test if WTC particle-induced nasal and neurologic tissue injury may result in unforeseen functional and behavioral outcomes.

Cardiovascular Prevention Among Young Adults with Congenital Heart Disease.

Purpose Of Review: There are over a million adults living with congenital heart disease (CHD) in the USA. There have been improvements in CHD management which have led to an expansion of the adult congenital heart disease (ACHD) population. There is a high prevalence of atherosclerotic cardiovascular disease (ASCVD) encountered in the aging ACHD population.

Miniaturized Drift Tube Ion Mobility Spectrometer with Ultra-Fast Polarity Switching.

Ion mobility spectrometers (IMS) are well suited for detecting trace gases down to levels at ppb and even ppt within 1 s of analysis time when using chemical ionization. The measuring principle is based on the separation and detection of the ionized constituents of a sample. Depending on the sample composition, certain ionization sources create both positive and negative analyte ions, but the simultaneous detection of both ion polarities usually requires two drift tubes.

Activity During the COVID-19 Pandemic in Children with Cardiac Rhythm Management Devices.

Decreased physical activity is associated with cardiovascular, metabolic and mental health disease. While decreases in physical activity during the COVID-19 pandemic have been described in the general population, there is a paucity of data regarding children with underlying cardiovascular disease. We hypothesized there would be a decrease in physical activity at the onset of the COVID-19 pandemic.

Electrospray ionization ion mobility spectrometer with new tristate ion gating for improved sensitivity for compounds with lower ion mobility.

An electrospray is a dispersed nebula of charged droplets produced under the influence of a strong electric field. The charged droplets subsequently result in ions in the gas phase. Therefore, electrospray is a commonly used method for transferring liquids to the gas phase while ionizing its constituents at the same time.

Probing the Electrolyte Transfer in Ultrathin Polypyrrole Films by In Situ X-ray Reflectivity and Electrochemistry.

This study reports on the potential-induced charge and mass transfer between an ultrathin polypyrrole (PPy) film and an electrolyte by simultaneous in situ X-ray reflectivity (XRR) and electrochemistry (EC) utilizing their sensitivity to electrons. An about 30 nm thin PPy film was deposited on a silicon single crystal by fast potential cycling, providing a dense film of an extraordinary small surface roughness. XRR was recorded from the PPy film in an aqueous 0.