[A new disposable, self-retaining, single-bladed vaginal speculum (author's transl)].

A new, disposable vaginal speculum has been tested clinically. It consists of a thin, elastic plastic sheet which, rolled into the shape of a narrow tube, can be introduced into the vagina. Due to its inherent elasticity, it unfolds and allows examination of the cervix uteri.

Biological action and half life in plasma or intramuscular sulprostone for termination of second trimester pregnancy.

Sulprostone levels in plasma, platelet function and clinical effects were examined in four patients after intramuscular injection of 500 microgram sulprostone for induction of missed and therapeutic abortion in the second trimester of pregnancy. The half life of sulprostone in plasma was 34 (30-45) minutes. The highest sulprostone levels were found 10 to 20 minutes after injection (0.

The use of sulprostone, a prostaglandin E2 derivative, in intrauterine fetal death and therapeutic abortion.

The prostaglandin E2 derivative Sulprostone was used in the management of intrauterine fetal death and in therapeutic abortion in advanced pregnancy. While with extraamniotic administration there was a success rate of 50% after 24 hours, the rate of success was 86% after intramuscular administration. A cervix-ripening effect was not always observed by means of intracervical injection of Sulprostone.

Dose-response study of fenoterol on uterine activity in labor at term.

Uterine hyperactivity can be treated with uterine relaxants. In order to establish the most satisfactory dosage for Fenoterol, several doses were administered intravenously to pregnant women during birth and the actions on uterine relaxation and on side effects were examined. Saline was injected in a group of patients as control.

Hemodynamic changes in placenta, myometrium and heart after administration of the uterine relaxant ritodrine.

The action of the uterine relaxant ritodrine on placental, myometrial and cardiac blood pools has been examined during spontaneous and oxytocin-induced uterine activity. 113mIndium was injected intravenously and the blood pools were measured by recording gamma-activity externally. After i.

The use of prostaglandin gel in obstetrics and gynecology.

The use of prostaglandin gel for therapeutic termination of second trimester pregnancy, the management of intrauterine fetal death, ripening of the cervix and induction of labour is reviewed. For these indications, prostaglandin gel is acceptable to patients, effective, and has low incidence of side effects and complications.

[Induction of labour in cases of intrauterine fetal death by cervical dilatation with a balloon and oxytocin titration (author's transl)].

In twelve cases of intrauterine fetal death labour was induced by combined treatment with an intra-cervical balloon and oxytocin infusion. The average induction-delivery time was approximately 11 hours. Acceptance of this method for induction of labour by the patients was satisfactory and the side effects were minor.

[Present day status in therapy of toxemia of pregnancy (author's transl)].

Since the causes of toxemia of pregnancy are unknown, therapy is still symptomatic and is now determined by the most recent knowledge of the pathophysiology of the disease. Rest, a balanced, predominantly protein-rich diet and avoidance of stress are recommended as prophylactic treatment of toxemia of pregnancy in patients with a predisposition of the condition. Early recognition of the symptoms of toxemia of pregnancy is of great importance.

[The action of Buphenin on uteroplacental haemodynamics (author's transl)].

The action of buphenin, a uterine relaxant from the group of adrenergic beta-mimetics, was examined on the blood pools of placenta, myometrium and heart, in 10 pregnant women. The method consisted of an i.v.

[Studies of the blood pool dynamic actions of dipyridamole in pregnancy (author's transl)].

The action of 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido-(5,4-d)pyrimidine (dipyridamole, Persantin) on utero-placental and cardiac blood pool dynamics was examined in 12 pregnant women. 113mIndium was injected i.v.

[Medical procedure in cases of rape (author's transl)].

Directions are given concerning the medical procedure in cases of rape. Besides emergency treatment for serious injury the patient should have her legal rights explained as well as the procedure for the forthcoming examination. A case history with special attention to the present case of rape is obtained.

Hematological studies in induction of abortion by extra-amniotic administration of sulproston.

The prostaglandin E2 derivative, Sulproston, was administered extra-amniotically for the induction of abortion in an average dosage of 200 microgram, in ten patients. With a success rate of 50%, the subjective side effects were very slight. Temperature, pulse rate, blood pressure and frequently of breathing did not change markedly.

Induction of labour with prostaglandin E2 gel in cases of intrauterine fetal death.

In established intrauterine fetal death, 20 patients were treated with prostaglandin E2 gel administered extraamniotically. The results were compared with those of another group of 20 patients who had received combined treatment. In this group, one or more of the following agents had been administered :- i.

[Problems in paediatric gynaecology (author's transl)].

The present survey deals with the physiological development and pathological disturbances of the female genital organs in childhood. The different phases in development of the female genitals are discussed under sections on the newborn phase, the resting phase and the maturing time. Then follows a description of the most important illnesses met with in practice including various types of vulvovaginitis, tumours, genital bleeding and accidental injuries.

Assessment of uteroplacental hemodynamics in complicated pregnancy.

Examination of the uteroplacental hemodynamics was performed on 109 occasions in women admitted to the hospital in the third trimester because of various complications of pregnancy. The radioactive tracer 113m In was injected intravenously and the build-up and equilibrium times were measured over the placenta, myometrium and heart. The placental build-up times were most informative, with prolonged values being recorded in about one quarter of these cases.

Studies on the haemodynamic action of complamin in pregnancy.

In the present work, an attempt has been made to verify whether Complamin improves placental circulation as suggested by several authors. Complamin was administered intravenously to patients in the last trimester of pregnancy and its action on blood pool dynamics was examined over 30 min. The results from 30 investigations showed that a significant reduction in uteroplacental blood pool occurred.

[Prostaglandins in reproductive physiology (author's transl)].

Up to the present time, the most extensive knowledge in prostaglandin research has been achieved in the field of reproductive physiology. It seems now certain that prostaglandins are involved in each phase of the reproductive process although their precise physiological functions cannot yet be completely explained. For example they are thought to play an important role in the hypothalamic -- pituitary system in the liberation of LHRH and in the ovary in steroid genesis, ovulation and luteolysis; also, in the non-pregnant uterus in the onset of menstruation while at conception both sperm and ovum transport are influenced by prostaglandins.

Actions of the uterine relaxant, fenoterol, on uteroplacental hemodynamics in human subjects.

The action of fenoterol, a uterine relaxant of the adrenergic beta-mimetic group of drugs, has been investigated on placental, myometrial, and cardiac blood pools. 113mIndium was injected intravenously and the blood pools were measured by recording gamma activity externally. In eight cases with oxytocin-induced labor, fenoterol inhibited the typical blood pool changes of labor, i.