Publications by authors named "Lippert F"

Objectives: To investigate the effect of water filter pitchers on the concentration of different minerals in tap water.

Methods: Nine water filter pitchers (A-I) were chosen based on consumer preferences and Amazon reviews. Each filter was tested for its ability to modify the concentrations of fluoride, calcium, magnesium, potassium, and sodium in tap water.

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Background: Chest pain is a frequent cause of health care contacts. We examined the prehospital management, in-hospital discharge diagnoses, and mortality of patients calling a non-emergency and emergency medical service with chest pain.

Methods: The Copenhagen Emergency Medical Services (EMS) consists of a non-emergency medical helpline (calls to 1813) and emergency medical service (1-1-2 calls).

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  • This study examined how common water filtration and purification systems (WFPS) are among residents in central Indiana and their effects on mineral concentrations in tap water.
  • Data was collected from 101 participants through a questionnaire and water sample analyses showed that 71% used WFPS, with pitcher filters being the most popular.
  • Results indicated that reverse osmosis systems significantly reduced mineral levels in tap water, while pitcher filters had minimal impact, highlighting the importance of choosing the right filtration system for health.
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Cerebrovascular disease is the second-leading cause of death and disability worldwide, with stroke being the most common cause. In ischemic stroke, several processes combine to produce immunosuppression, leaving the post-stroke body susceptible to infection, which in turn affects neuroinflammation. Interleukin-33 (IL-33), a member of the interleukin-1 family (IL-1), functions as a modulator of immune responses and inflammation, playing a crucial role in the establishment of immunologic responses.

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Stroke is the second most common cause of death and one of the most common causes of disability worldwide. The intestine is home to several microorganisms that fulfill essential functions for the natural and physiological functioning of the human body. There is an interaction between the central nervous system (CNS) and the gastrointestinal system that enables bidirectional communication between them, the so-called gut-brain axis.

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  • Early percutaneous coronary intervention (PCI) is crucial for treating STEMI, yet the impact of delays in PCI timing has not been thoroughly evaluated.
  • A study in Copenhagen analyzed the effects of delays caused by system factors or hospital distance on outcomes for STEMI patients, finding significant differences based on time from distress call to PCI.
  • Results showed that delays over one hour substantially increased the risk of death, recurrent heart attacks, or heart failure, highlighting the importance of reducing the time from the first contact to PCI for better patient outcomes.
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  • * The Cincinnati Childhood Allergy and Air Pollution Study analyzed urine samples and blood DNA methylation to investigate the impact of fluoride on the epigenome in early adolescents, focusing on CpG loci related to DNA methylation.
  • * Results showed that higher fluoride concentrations were linked to differential methylation of specific genes associated with psychiatric outcomes and cognition, particularly in females, indicating that fluoride may influence epigenetic changes during adolescence, but further research is needed to understand the functional impacts.
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Objectives: In Denmark, the use of bicycles is widespread, and head injuries are often seen in cyclists involved in collisions. Despite the well-known effects of using a helmet to reduce head injuries, using helmets is not mandatory in Denmark. The primary objective of this study was to provide data regarding injury outcomes and helmet usage.

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  • The study aimed to explore how the mineral distribution in enamel affects the effectiveness of silver diammine fluoride (SDF) in remineralizing and staining caries lesions.
  • A laboratory experiment tested different treatments (SDF, fluoride varnish, and deionized water) on various types of lesions created in bovine enamel, analyzing changes in mineral levels and color.
  • Results showed that treatment type and lesion protocol significantly affected mineral loss and color changes, with SDF leading to increased mineral gain in the surface zone, while staining from SDF varied based on lesion type.
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Ischemic stroke occurs due a blockage in the blood flow to the brain, leading to damage to the nervous system. The prevalent morbidities resulting from stroke include post-stroke infection, as sepsis. Additionally, oxidative stress is recognized for inducing functional deficits in peripheral organs during sepsis.

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Objectives: he aim of this in vitro study was to evaluate the effects of some bottled waters on fluoride toothpaste efficacy in enhancing caries lesion remineralization.

Methods: Early caries lesions were created in bovine enamel specimens and stratified into treatment groups based on Vickers surface microhardness (VHN). The present study followed a two (fluoride and fluoride-free toothpaste) by five (four bottled waters and tap water) factorial design.

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This study used demographic data in a novel prediction model to identify areas with high risk of out-of-hospital cardiac arrest (OHCA) in order to target prehospital preparedness. We combined data from the nationwide Danish Cardiac Arrest Registry with geographical- and demographic data on a hectare level. Hectares were classified in a hierarchy according to characteristics and pooled to square kilometers (km2).

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  • Out-of-hospital cardiac arrest (OHCA) is a common and deadly event in Denmark, with around 5000 cases annually, and survival within 30 days is linked to symptoms experienced before the event.
  • The study focused on OHCAs witnessed by emergency medical services in Denmark from 2016-2018, analyzing data to assess the survival odds related to prodromal complaints while considering factors like age and sex.
  • Results indicated that symptoms like chest pain and heart palpitations significantly improved survival odds, whereas signs of unresponsiveness or bluish skin reduced the likelihood of surviving 30 days post-arrest.
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  • This study aimed to explore how different toothbrush head designs and the abrasiveness of toothpaste affect the formation of non-carious cervical lesions (NCCLs) on teeth in a lab setting.
  • Researchers tested 15 combinations of toothbrush configurations and toothpaste abrasivity on extracted teeth to assess dental volume loss after simulated brushing.
  • Results showed that certain toothbrushes paired with high-abrasive toothpaste led to greater tooth damage, with specific head designs like flat-trimmed causing the most wear, while others like cross-angled/flex showed less damage with low-abrasive toothpaste.
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Introduction: This in vitro study aimed to evaluate the effect of three different chemical agents on stain removal and mineral uptake of artificial dentin caries (ADC) lesions treated with silver diamine fluoride (SDF).

Methods: Baseline L*a*b* values were determined in polished human permanent dentin blocks, and ADC lesions were induced with an acid gel for 1 week. Samples were assigned to four groups; in three groups, half of each sample received SDF (30% SDF for 3 min), while the other half received SDF followed by a bleaching treatment protocol (garlic extract, bentonite, or 35% hydrogen peroxide).

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Background: The knowledge of prognosis following out-of-hospital cardiac arrest (OHCA) in patients with heart failure heart failure (HF) is sparse. The objective of this study was to compare the outcome after OHCA among patients with and without HF.

Methods: We studied 45,293 patients who were included for the Danish cardiac arrest registry between 2001 and 2014.

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  • * Four types of denture materials (compression-molded, injection-molded, 3D-printed, and milled) were tested with either polished or glazed finishes, followed by 50,000 brushing strokes to simulate wear.
  • * Results showed that polished compression-molded materials had the highest hardness, while glazed treatments enhanced hardness across the board, but roughness increased after brushing, especially more with polished surfaces.
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Objective: This investigation describes the effects of 5% sodium fluoride varnish and 38% silver diamine fluoride on demineralization protection of human enamel lesions of three different severities after a secondary acid challenge.

Study Design: Specimens underwent color and enamel surface microhardness change measurements after demineralization and treatment events. Transverse microradiography was conducted following the secondary demineralization.

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Importance: Young children often fall ill, leading to concern among their caregivers and urgent contact with health care services.

Objective: To assess the effectiveness and safety of video tutorials to empower caregivers in caring for acutely ill children.

Design, Setting, And Participants: Caregivers calling the out-of-hours Medical Helpline 1813 (MH1813), Emergency Medical Services Capital Region, Denmark, and their children aged 0.

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Introduction: In Denmark, multiple national initiatives have been associated with improved bystander defibrillation and survival following out-of-hospital cardiac arrest (OHCA) in public places. However, OHCAs in residential neighbourhoods continue to have poor outcomes. The Cardiac Arrest in Residential Areas with MoBile volunteer responder Activation trial aims to improve bystander defibrillation and survival following OHCA in residential neighbourhoods with a high risk of OHCA.

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Background And Importance: Ensuring prompt ambulance responses is complicated and costly. It is a general conception that short response times save lives, but the actual knowledge is limited.

Objective: To examine the association between the response times of ambulances with lights and sirens and 30-day mortality.

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Background And Importance: Telephone calls are often patients' first healthcare service contact, outcomes associated with waiting times are unknown.

Objectives: Examine the association between waiting time to answer for a medical helpline and 1- and 30-day mortality.

Design, Setting And Participants: Registry-based cohort study using phone calls data (January 2014 to December 2018) to the Capital Region of Denmark's medical helpline.

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  • - The study aimed to evaluate the microhardness of enamel treated with two different pH bleaching agents and the impact of fluoride therapy before and after bleaching treatments.
  • - Eighty bovine incisors were split into eight groups to test various combinations of bleaching agents and fluoride treatments, with hardness measured at three intervals and assessed using statistical analysis.
  • - Results indicated that Pola Office bleaching resulted in the greatest enamel softening, while applying 2% NaF gel afterward effectively restored some enamel hardness, although the fluoride treatment after Pola Office+ had minimal benefits.
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Purpose: To describe and discuss the benefits and drawbacks of various dental caries diagnostic techniques, including the use of intraoral scanners for caries diagnosis based on near-infrared imaging (NIR) technology.

Material And Methods: A MEDLINE search from 1980-2023 focused on dental caries diagnostic techniques, emphasizing intraoral scanners using NIR technology. Alternative caries detection methods were also evaluated for their advantages and limitations, enabling a comparison with NIR.

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This study tested a novel in vitro dental erosion-abrasion model and the performance of cross-polarization optical coherence tomography (CP-OCT) in longitudinally monitoring the simulated lesions. Thirty human enamel specimens were prepared and randomized to receive three dental erosion-abrasion (EA) protocols: severe (s-EA, lemon juice/pH:2.5/4.

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