Mechanical properties and mechanisms of soda residue and fly ash stabilized soil.

To improve the utilization rates of soda residue (SR) and fly ash (FA), reduce environmental pollution, and enhance the mechanical properties of marine clay (MC), this study proposes mixing SR, FA, and MC with cement and /or lime to prepare soda residue-fly ash stabilized soil (SRFSS). Using an orthogonal design for the proportions, the study analyzes the compaction performance, unconfined compressive strength (UCS), and shear strength of SRFSS. The influence of various factors on the mechanical properties of SRFSS was investigated through range and variance analyses.

Factors influencing parents' educational anxiety of primary and secondary school students: evidence from parents in China.

Background: Current research has focused on exploring the sources of parents' anxiety about children's education (PAE), and we continue in this direction by exploring the factors influencing parental educational anxiety in primary and secondary school students and the interactions among them.

Methods: Parental Educational Anxiety Measurement Questionnaire was used to measure the level of PEA. Pearson correlation coefficient analysis was used to examine the correlation between the level of PAE and the demographic variables.

Soil fluoride enrichment process and the possible adaptation prevention principle in coal-burning fluorosis area in Southwest China.

Coal-burning fluorosis prevails in southwest China and other provinces. Although clay used as binder of briquettes was proven to cause coal-burning fluorosis, its enrichment processes remain unknown. The soils and rocks on typical geological units were sampled and simulation experiments were performed to detect the forming process of high-fluoride clay.

Leveraging plant-derived nanovesicles for advanced nucleic acid-based gene therapy.

Gene therapy has evolved into a pivotal approach for treating genetic disorders, extending beyond traditional methods of directly repairing or replacing defective genes. Recent advancements in nucleic acid-based therapies-including mRNA, miRNA, siRNA, and DNA treatments have expanded the scope of gene therapy to include strategies that modulate protein expression and deliver functional genetic material without altering the genetic sequence itself. This review focuses on the innovative use of plant-derived nanovesicles (PDNVs) as a promising delivery system for these nucleic acids.

Muscle-Derived Bioactive Factors: MyoEVs and Myokines.

Overview of the functions and applications of myokines and MyoEVs.

The effect of light therapy on insomnia: A systematic review and meta-analysis.

Purpose: Light is a crucial factor influencing sleep arousal patterns. This meta-analysis investigates the efficacy of light therapy (LT) for insomnia treatment.

Methods: Five electronic databases were independently searched by two reviewers until August 2024.

Determination of four forms of plasma thiol amino acids in individuals with chronic kidney disease by UPLC-MS/MS.

The study introduces a robust analytical method based on UPLC-MS/MS for quantifying thiol amino acids, including cysteine (Cys), cysteinylglycine (CG), homocysteine (Hcy), and glutathione (GSH), in their total and total free forms within human plasma. An optimized blank matrix was employed for accurate quantification of endogenous compounds. The method exhibited excellent linearity, precision, accuracy, recovery, and stability, making it highly suitable for plasma analysis.

[Screening and identification of host proteins interacting with the non-structural protein 15 (Nsp15) of porcine epidemic diarrhea virus].

To screen and identify the key host proteins interacting with the non-structural protein 15 (Nsp15) of porcine epidemic diarrhea virus (PEDV). The IP/pull-down assay and mass spectrometry were employed to screen and identify the host proteins interacting with Nsp15. The interaction between the host protein and Nsp15 was studied by co-immunoprecipitation and laser scanning confocal microscopy.

Comparative morphology and mitogenomics of freshwater mussels Koreosolenaia, Parvasolenaia, and Sinosolenaia (Bivalvia: Unionidae: Gonideinae).

Background: Amidst the escalating loss of global biodiversity, freshwater mussels (family Unionidae) have become one of the most imperiled animal groups. Acquiring more biological and phylogenetic information on understudied taxa constitutes a pivotal aspect of conservation biology. Consequently, a comprehensive examination was conducted on Koreosolenaia, Parvasolenaia, and Sinosolenaia from China encompassing morphology, anatomy, distribution, and molecular systematics to provide theoretical support for future species endangerment assessments and biodiversity conservation.

Role of anthropogenic forcing in Antarctic sea ice variability simulated in climate models.

Antarctic sea ice extent has seen a slight increase over recent decades, yet since 2016, it has undergone a sharp decline, reaching record lows. While the precise impact of anthropogenic forcing remains uncertain, natural fluctuations have been shown to be important for this variability. Our study employs a series of coupled model experiments, revealing that with constant anthropogenic forcing, the primary driver of interannual sea ice variability lies in deep convection within the Southern Ocean, although it is model dependent.

The ability of virtual noncontrast images to remove intrinsic and external iodine from the thyroid via dual-layer spectral detector computed tomography.

Background: Virtual noncontrast (VNC) images generated by dual-layer spectral computed tomography (DLCT) remove iodine influence from enhanced images to simulate true noncontrast (TNC) images. Previous research has demonstrated the high comparability of abdominal VNC images with TNC images, suggesting their potential as substitutes. Given the thyroid's significant iodine content, this study evaluated the efficacy of VNC images for removing both intrinsic and extrinsic iodine through an analysis of computed tomography (CT) attenuation and iodine density in TNC and enhanced VNC thyroid images.

Ethylene response transcription factor 5 (ERF5) enhances defense against tobacco curly shoot virus and associated betasatellite (TbCSV/TbCSB) in Nicotiana benthamiana.

Begomovirus/betasatellite disease complex significantly threatens global crop production. Identifying potential plant antiviral genes is crucial for disease control. Nicotiana benthamiana is susceptible to viruses and contains 266 ethylene response transcription factors (ERFs).

An Analysis of the Efficacy of the Health Butler Application and Intelligent Accompaniment Systems in Smart Outpatient Services Based on Patient Feedback.

Objective: This study aims to explore the efficacy of a smart outpatient service system incorporating the Health Butler application and Intelligent Accompaniment based on patients' feedback.

Methods: A total of 1000 outpatients from Shenzhen Third People's Hospital were randomly selected in May 2023 and November 2023 to provide feedback before and after implementing the smart outpatient service system consisting of the Health Butler app and Intelligent Accompaniment. The changes in the patient's awareness of the medical treatment process, average waiting time, satisfaction with the experience of seeking medical treatment, and trust in medical services offered based on patient feedback were compared pre- and post-implementation.

LncRNA-FGD5-AS1 promotes 5-Fu resistance of cervical cancer cells through modulating the miR-130a-3p-YTHDF2 axis.

Cervical cancer is one of the most common gynecologic malignancies worldwide. 5-Fluorouracil (5-Fu) is a widely used anticancer drug for various cancers, but the development of 5-Fu resistance poses a challenge in treating cervical cancer patients. This study examined the roles and molecular mechanisms of LncRNA-FGD5-AS1 in 5-Fu resistant cervical cancer cells through in vitro and in vivo experiments.

Effects of surfactin stress on gene expression and pathological changes in Spodoptera litura.

Spodoptera litura (S. litura) is a polyphagous pest of the family Lepidoptera, which causes damage and yields losses to many crops. The long-term use of chemical pesticides for control not only seriously threatens environmental health, but also causes S.

TaFAR9 and TaFAR10 synergistically regulate fertility conversion of photo-thermo-sensitive genic male sterility lines in wheat by modulating ROS homeostasis.

Photo-thermo-sensitive genic male sterility (PTGMS), which exhibits varying fertility levels under different environmental conditions, is a crucial method for heterosis utilization in wheat. However, the mechanisms underlying fertility conversion remain unclear. In the study, three BS type PTGMS lines were analyzed to study fertility conversion characteristics.

AIM2 promotes the progression of HNSCC via STAT1 mediated transcription and IL-17/MAPK signaling.

Chronic inflammation has been recognized as one of the hallmarks of head and neck squamous cell carcinoma (HNSCC), Absent In Melanoma 2(AIM2) has emerged as important regulators of chronic inflammatory, and participated in initiation, progression of kinds of human cancers. Nonetheless, the biological functions and underlying mechanisms of AIM2 in HNSCC remain inadequately understood. Based on the bioinformatics analysis of public databases, we identified elevated AIM2 expression in HNSCC, which positively correlates with disease stage and HPV infection, thereby possessing both diagnostic and prognostic significance.

The relationships among illness perceptions, dyadic coping and illness management in breast cancer patients and their spouses: A dyadic longitudinal mediation model.

Objectives: To describe and compare dyads' illness perceptions, dyadic coping and illness management among breast cancer patients and their spouses. In addition, we explore the direct actor and partner effects of illness perception on illness management, and whether this association is mediated by dyadic coping.

Design: A descriptive and longitudinal study.

Preliminary investigation of the anti- activity of Triphala.

Background: Triphala, is a composite of three individual botanical drugs: , , and . It exhibits properties such as heatclearing, anti-inflammatory, anti-fatigue, antioxidant, and antibacterial effects,making it extensively utilized in India and Tibet. It has been found to exhibitinhibitory effects on (); however, further comprehensive research is still needed to elucidate its specific antibacterial mechanism.

Development of a monoclonal antibody specifically recognizing a linear epitope on the E1 protein of Getah virus.

Getah virus (GETV) is a mosquito-borne alphavirus that can cause disease outbreaks in domesticated mammals. The E1 protein of GETV plays a crucial role in mediating the fusion of viruses and host cells. In this study, the recombinant GETV E1 protein was expressed and administered to BALB/c mice.

Joint Analysis of CCAAT/Enhancer-Binding Protein Beta and Interleukin 1 Beta in the Treatment and Prognosis of Diffuse Large B-Cell Lymphoma.

Objective: The purpose of this study is to investigate the correlation between elevated levels of CCAAT/enhancer-binding protein beta () gene expression and unfavorable outcomes in diffuse large B-cell lymphoma (DLBCL). The goal is to elucidate potential therapeutic targets associated with this relationship.

Methods: Differential expression and survival analyses were conducted using data from the Gene Expression Omnibus (GEO) database.

Mature compost enhanced the harmlessness level in co-composting swine manure and carcasses in large-scale silo reactors.

This study aimed to investigate the impact of incorporating mature compost on the harmlessness and maturity level of composting from swine manure and carcasses from industrialized pig farms in continuously running large-scale silo reactor systems. The potential human or animal bacterial pathogens and core bacterial community in composting were analyzed by high-throughput sequencing of 16S rRNA gene amplicons. The results showed that the addition of mature compost in the GD group significantly increased the temperature of all depths, the accumulated temperature of compost, and the germination index (75.