Publications by authors named "Liping Shen"

This study developed PQSp wound dressing hydrogels (S0-S6) using polyvinyl alcohol (PVA), quaternary chitosan (QCS), and sodium alginate (SA) as the matrix, with the addition of coconut mesocarp polyphenol (P-CTP, 0.1 %, 0.5 %, and 1.

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  • Listeria monocytogenes (LM) is a zoonotic pathogen responsible for listeriosis, a foodborne illness linked to contaminated food or feed.
  • An African lion from a Shanghai zoo was analyzed after its death, with LM infection suspected due to observed symptoms and pathological changes.
  • The infection was confirmed through advanced techniques like polymerase chain reaction and whole genome sequencing, marking the first documented case of LM infection in an African lion in China.
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Background: The Chinese beverage industry is experiencing rapid growth, particularly in the popularity of non-sugar sweetened beverages (NSSs) and ready-to-drink beverages (RSBs). This study aimed to assess current consumption patterns and determinants of various beverage types among retail visitors.

Methods: A total of 44 observation points, including 22 supermarkets and 22 convenience stores, were randomly selected across Shanghai.

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Purpose: To evaluate the safety and efficacy of transurethral holmium laser enucleation of the prostate (HoLEP) compared to bipolar transurethral resection of the prostate (bTUR-P) in the treatment of benign prostatic hyperplasia (BPH).

Methods: A total of 220 BPH patients hospitalized from January 2022 to September 2023 were included in this study. These patients were randomly assigned to HoLEP and bTUR-P groups, with 110 participants in each group.

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Purpose: The study aimed to investigate the correlation between baseline serum levels of high mobility group box 1 (HMGB1) and the recurrence of acute ischemic stroke (AIS).

Patients And Methods: A total of 544 AIS patients were enrolled and followed up monthly. Serum HMGB1 levels were measured using enzyme-linked immunosorbent assay (ELISA).

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Background: Since 1992, when recombinant hepatitis B vaccine was introduced in China, government health officials have used nationally representative serological surveys to monitor progress in prevention and control of hepatitis B. In 2020, we conducted the fourth seroepidemiological survey, which for the first time included medical evaluation of the clinical status of HBsAg positive subjects over the age of 15 and their medical management. We report survey results in comparison with the three previous surveys.

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  • Over the last century, environmental changes have shaped wheat spike morphology, which is key for adaptation and yield, but the specifics of these changes are largely unexplored.
  • This study analyzes 16 spike traits in 830 wheat varieties from 1900 to 2020, finding increases in spike weight, grain number, and kernel weight, while spike length remained unchanged.
  • Genetic analyses identified nearly 50,000 significant genetic markers linked to spike traits, revealing their genetic basis and geographical differentiation, thus providing insights for improving wheat adaptation to environmental changes.
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  • Previous research on maternal diets and their impact on birth weight is limited, especially in non-Western populations like China, leading to the aim of this study to investigate the relationship.
  • The study involved 4,184 mother-child pairs and employed a comprehensive food frequency questionnaire to identify three main dietary patterns: plant-based, animal-based, and processed foods, which explained a significant portion of dietary variance.
  • Results indicated that higher adherence to a plant-based diet was linked to an increased risk of macrosomia (large birth weight), particularly due to potato consumption, while animal-based and processed diets showed no significant effects on birth weight outcomes.
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Background: As the global consumption of sugary and non-sugar sweetened beverages continues to rise, there is growing concern about their health impacts, particularly among pregnant women and their offspring.

Objective: This study aimed to investigate the consumption patterns of various beverages among pregnant women in Shanghai and their potential health impacts on both mothers and offspring.

Method: We applied a multi-stage random sampling method to select participants from 16 districts in Shanghai.

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Background: The prevalence of sarcopenia is increasing in worldwide with accelerated aging process. The high dietary protein intakes are associated with improved muscle mass and strength especially in Asian countries. However, there are few researches on amino acid levels or mechanism exploration.

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  • Small nucleolar RNAs (snoRNAs) were once thought to mainly assist in modifying ribosomal RNA for ribosome production, but they also play roles in various biological processes beyond this traditional view.
  • Recent findings indicate that snoRNAs participate in the DNA damage response (DDR), a crucial mechanism for preserving genomic stability and preventing diseases.
  • The review discusses snoRNA biosynthesis, their regulatory mechanisms, their involvement in DDR, and their potential applications in diagnosing and treating diseases, highlighting their importance in genomic stability and pathology.
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Aims: The purpose of this study was to find out the relation between visceral adipose index (VAI) levels and stress urinary incontinence (SUI) in adult women.

Methods: From the National Health and Nutrition Examination Survey (NHANES) 2007-2020, females aged 20 or above were identified for this study. Visceral adiposity was determined using the VAI score, and the assessment of urinary incontinence was carried out through a correlation questionnaire.

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  • The study aimed to assess the effectiveness of traditional Chinese medicine (TCM) in improving the survival of patients with stage IIIA non-small cell lung cancer (NSCLC) compared to observation after chemotherapy.
  • A total of 75 patients were randomly assigned to receive TCM or simply be observed for 12 months, focusing on disease-free survival and quality of life.
  • Results showed that TCM significantly improved disease-free survival rates and overall health scores after three months, while also reducing various symptoms, although there was no notable difference in regulatory T cells between the two groups.
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  • * Researchers found specific miRNAs (mmu-miR-374c-5p, mmu-miR-194-5p, mmu-miR-192-5p, and mmu-miR-223-3p) that were expressed in mouse serum after lethal radiation exposure, particularly following 10 Gy irradiation.
  • * Notably, mmu-miR-192-5p levels reflected recovery post-treatment and correlated with survival rates, suggesting its potential as a biomarker to enhance medical responses during nuclear accidents.
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Radiotherapy is essential for treating colorectal cancer (CRC), especially in advanced rectal cancer. However, the low radiosensitivity of CRC cells greatly limits radiotherapy efficacy. Small nucleolar RNAs (snoRNAs) are a class of noncoding RNA that primarily direct post-transcriptional modifications of ribosomal RNAs (rRNAs), small nuclear RNAs (snRNAs), and other cellular RNAs.

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Objective: It's crucial to identify an easily detectable biomarker that is specific to radiation injury in order to effectively classify injured individuals in the early stage in large-scale nuclear accidents.

Methods: C57BL/6J mice were subjected to whole-body and partial-body γ irradiation, as well as whole-body X-ray irradiation to explore the response of serum sSelectin-L to radiation injury. Then, it was compared with its response to lipopolysaccharide-induced acute infection and doxorubicin-induced DNA damage to study the specificity of sSelectin-L response to radiation.

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Eleven previously undescribed abietane-type diterpenoids, named caryopincanoids A-K (1-11), together with five known compounds, were isolated from the EtOH extract of the aerial parts of Caryopteris incana (Thunb.) Miq. Their structures were elucidated on the basis of comprehensive spectroscopic data, NMR calculations, and ECD calculations.

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The majority of pigeon paramyxovirus type 1 (PPMV-1) strains are generally non-pathogenic to chickens; however, they can induce severe illness and high mortality rates in pigeons, leading to substantial economic repercussions. The genomes of 11 PPMV-1 isolates from deceased pigeons on meat pigeon farms during passive monitoring from 2009 to 2012 were sequenced and analyzed using polymerase chain reaction and phylogenetic analysis. The complete genome lengths of 11 isolates were approximately 15,192 nucleotides, displaying a consistent gene order of 3'-NP-P-M-F-HN-L-5'.

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Ethnopharmacological Relevance: Leonurus japonicus Houtt. (Labiatae), commonly known as Chinese motherwort, is a herbaceous flowering plant that is native to Asia. It is widely acknowledged in traditional medicine for its diuretic, hypoglycemic, antiepileptic properties and neuroprotection.

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Disulfidptosis was recently reported to be caused by abnormal disulfide accumulation in cells with high SLC7A11 levels subjected to glucose starvation, suggesting that targeting disulfidptosis was a potential strategy for cancer treatment. We analyzed the relationships between gene expression and mutations and prognoses of patients. In addition, the correlation between gene expression and immune cell infiltration was explored.

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While oral administration offers safety benefits, its therapeutic efficacy is hindered by various physiological factors within the body. In this study, a novel approach was explored using a matrix consisting of 2 % chitosan and 2 % gelatin, with citric acid (CA) serving as a green cross-linking agent (ranging from 0.4 % to 1.

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  • Physical exercise can help reduce anxiety, but scientists are still figuring out how it works in the brain.
  • Researchers found a group of brain cells that connect movement (motor) and feelings (emotions) to help lower anxiety.
  • When animals do different types of physical challenges, certain brain parts work together to create a calming effect, suggesting that tough exercises are really good for managing anxiety.
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