Chemistry and biology of natural stilbenes: an update.

Covering: 2009 up to the end of 2023Stilbenes, an emblematic group of polyphenols, have attracted the attention of numerous researchers owing to their intriguing polycyclic architectures and diverse bioactivities. In this updated review, natural stilbenes were analysed, especially oligomeric stilbenes, which are an emblematic group of polyphenols that harbor intriguing polycyclic architectures and diverse bioactivities compared with those previously anticipated. Oligomeric stilbenes with unique skeletons comprise a large majority of natural stilbenes owing to their structural changes and different substitutions on the phenyl rings.

Valorization of Corn Straw for Production of Glucose by Two-Step Depolymerization.

Depolymerization of the cellulose part in lignocellulose to glucose is a significant step for lignocellulose valorization. As one of the main by-products of agricultural biomass in crop-producing filed, valorization of corn straw has attracted considerable attention. In this study, a two-step depolymerizing strategy of high-pressure CO-HO pretreatment and oxidation-hydrolysis was applied for selective depolymerization of the cellulose component of corn straw to glucose production.

Stepwise Synthesis of Low-Symmetry Hexacationic Pyridinium Organic Cages.

An efficient approach was developed for the synthesis of the well-known BlueCage by pre-bridging two 2,4,6-tris(4-pyridyl)-1,3,5-triazine (TPT) panels with one linker followed by cage formation in a much improved yield and shortened reaction time. Such a stepwise methodology was further applied to synthesize three new pyridinium organic cages, , , and , where the low-symmetry cages and with angled panels demonstrated better recognition properties toward 1,1'-bi-2-naphthol (BINOL) than the high-symmetry analogue featuring parallel platforms.

54 K Spin Transition Temperature Shift in a FeL Octahedral Cage Induced by Optimal Fitted Multiple Guests.

Spin-crossover (SCO) coordination cages are at the forefront of research for their potential in crafting next-generation molecular devices. However, due to the scarcity of SCO hosts and their own limited cavities, the interplay between the SCO host and the multiple guests binding has remained elusive. In this contribution, we present a family of pseudo-octahedral coordination cages (M, M = Zn, Co, Fe, and Ni) assembled from a tritopic tridentate ligand with metal ions.

Subtle adjustments for constructing multi-nuclear luminescent lanthanide organic polyhedra with triazole-based chelates.

Controlled self-assembly of predetermined multi-nuclear lanthanide organic polyhedra (LOPs) still presents a challenge, primarily due to the unpredictable coordination numbers and labile coordination geometries of lanthanide ions. In this study, through introducing triazole-based chelates to increase the chelating angle of -symmetric linear ligands and stabilize the coordination geometry of Eu(III) centers, ML-type (M = Eu, L = ligand) tetrahedra were efficiently synthesized, especially a biphenyl-bridged ligand which is well known to form ML-type helicates. A series of LOPs were formed and characterized by high-resolution electrospray ionization time-of-flight mass spectroscopy (ESI-TOF-MS) and X-ray crystallography.

Tannins in Phyllanthus emblica L. improves cisplatin efficacy in lung cancer cells by boosting endoplasmic reticulum stress to trigger immunogenic cell death.

Background: Lung cancer is one of the deadliest cancers world-wide and immunotherapy has been considered as a promising therapeutic strategy. Previously, our study found that tannins in Phyllanthus emblica L. (PTF) could inhibit the growth of tumor by activating the immune response in liver cancer, and also exhibited a cytotoxicity on human lung cancer cells A549, H460, H1703 in vitro.

Excited-Multimer Mediated Supramolecular Upconversion on Multicomponent Lanthanide-Organic Assemblies.

Upconversion (UC) is a fascinating anti-Stokes-like optical process with promising applications in diverse fields. However, known UC mechanisms are mainly based on direct energy transfer between metal ions, which constrains the designability and tunability of the structures and properties. Here, we synthesize two types of LnL-type (Ln for lanthanide ion; L for organic ligand L or L) lanthanide-organic complexes with assembly induced excited-multimer states.

Counteranion-mediated efficient iodine capture in a hexacationic imidazolium organic cage enabled by multiple non-covalent interactions.

Developing efficient adsorbents to capture radioactive iodine produced from nuclear wastes is highly desired. Here we report the facial synthesis of a hexacationic imidazolium organic cage and its iodine adsorption properties. Crucial role of counteranions has been disclosed for iodine capture with this cage, where distinct iodine capture behaviors were observed when different counteranions were used.

Correction: leaf polysaccharides exert anti-lung cancer effects upon targeting TLR4 to reverse the tumor-associated macrophage phenotype and promote T-cell infiltration.

Correction for ' leaf polysaccharides exert anti-lung cancer effects upon targeting TLR4 to reverse the tumor-associated macrophage phenotype and promote T-cell infiltration' by Shukai Wang , , 2023, , 4607-4620, https://doi.org/10.1039/D2FO03685A.

Controlled Self-Assembly, Isomerism, and Guest Uptake/Release of Charge-Reversible Lanthanide-Organic Octahedral Cages.

Charge plays a crucial role in the function of molecular and supramolecular systems, but coordination hosts capable of orthogonal charge regulation remain elusive so far. In this study, we report the condition-dependent self-assembly of charge-reversible lanthanide-organic tetra-capped octahedral cages, i.e.

Self-Assembly of Triple-Stranded Lanthanide Molecular Quasi-Lantern Containing 2,2'-Bipyridine Receptor: Luminescence Sensing and Magnetic Property.

Ln-type supramolecular architectures have received significant attention recently due to their unique magnetism and optical properties. Herein, we report the triple-stranded Ln-type lanthanide molecular quasi-lanterns, which are fabricated by the deprotonation self-assembly of a linear ligand featuring a β-diketone chelating claw and 2,2'-bipyridine (bpy) moiety with lanthanide ions (Ln = Eu and Dy). The crystal structure analysis indicates that Eu and Dy ions are all coordinated by eight oxygen donors but in different coordination geometries.

Hierarchical subcomponent self-assembly of covalent triple-stranded complexes with 3d-4f vertices: luminescence and magnetic properties.

Well-defined 3d-4f heterometallic supramolecular architectures have attracted attention because of their applications in the field of luminescence and magnetism. However, covalent metallo-supramolecular discrete complexes, decorated with hetero-metallic vertices, have never been reported because of the difficulties in design and control. Herein, we report a series of covalent metallo-supramolecular discrete complexes with 3d-4f vertices synthesized by hierarchical subcomponent self-assembly of tris(2-aminoethyl)amine, 2,6-diformyl--cresol, and lanthanide ions (Ln) with different amines and transition metal ions.

A PdL cage containing Brønsted-base active sites for the one-pot photooxidation/Knoevenagel condensation reaction.

Brønsted-base active sites on a PdL cage facilitates enhanced catalytic efficiency, wide substrate scope and high turnover number (TON) for the one-pot photooxidation/Knoevenagel condensation reaction under mild conditions.

leaf polysaccharides exert anti-lung cancer effects upon targeting TLR4 to reverse the tumor-associated macrophage phenotype and promote T-cell infiltration.

Tumor-associated macrophages (TAMs) participate in tumorigenesis, growth, invasion as well as metastasis by facilitating an immunosuppressive tumor microenvironment. Reversing the pro-tumoral M2 phenotype of TAMs has become a hot spot in advancing cancer immunotherapy. In the current study, the content of leaf polysaccharides (MOLP) was determined and characterized, along with the anti-cancer mechanism of MOLP studied in a Lewis lung cancer (LLC) tumor-bearing mouse model and bone marrow-derived macrophages.

Embedding Lanthanide Organic Polyhedra into Mesoporous Silica Nanoparticles for the Photocatalytic Degradation of Organic Dyes.

Organic pollutants cause severe environmental problems because of their damage to human health and ecological systems. Photocatalytic degradation of persistent organic pollutants is of great importance to address these hazards. Herein, we report a lanthanide organic polyhedra-based hybrid material Gd L ⊂MSN with the capability of photocatalytic dye degradation.

The Therapeutic Effect and the Potential Mechanism of Flavonoids and Phenolics of Lam. Leaves against Hyperuricemia Mice.

The aim of this study is to evaluate the anti-hyperuricemia effect and clarify the possible mechanisms of flavonoids and phenolics of MOL (MOL-FP) in mice. Hyperuricemia mice were generated via intraperitoneal (i.p.

Dinuclear mono-bridged or polymeric lanthanide complexes from one ligand: structural transformation and chiral induction.

We designed and synthesized a semi-rigid bis-tridentate ligand which could undergo a -to- conformational transition when coordinated onto lanthanum ions through the rotation of the single bond on the central terphenyl bridge. By adjusting the metal/ligand ratio, a single-ligand bridged dinuclear complex La and an infinitely extending two-dimensional layered metal organic polymer (La) can be obtained. Through the induction of the chiral auxiliary ligand , these two achiral assemblies could both be transformed into the chiral mononuclear three-component complex La.

Evaluation of the chemical profile from four germplasms sources of Pruni Semen using UHPLC-LTQ-Orbitrap-MS and multivariate analyses.

Pruni Semen, the seed of several unique Prunus plants, is a traditional purgative herbal material. To determine the authentic sources of Pruni Semen, 46 samples from four species were collected and analyzed. Ten compounds including multiflorin A (Mul A), a notable purative compound, were isolated and identified by chemical separation and nuclear magnetic resonance spectroscopy.

Stereocontrolled Self-Assembly of Ln(III)-Pt(II) Heterometallic Cages with Temperature-Dependent Luminescence.

Structurally well-defined discrete d/f heterometallic complexes show diverse application potential in electrooptic and magnetic materials. However, precise control of the component and topology of such heterometallic compounds with fine-tuned photophysical properties is still challenging. Herein, we report the stereocontrolled syntheses of a series of Ln-Pt heterometallic cages through coordination-driven self-assembly of enantiopure alkynylplatinum-based metalloligands (L, L) with lanthanide ions (Ln = Eu, Yb, Nd, Lu).

An Organo-Palladium Host Built from a Dynamic Macrocyclic Ligand: Adaptive Self-Assembly, Induced-Fit Guest Binding, and Catalysis.

Artificial hosts with rich conformational dynamics are attractive to supramolecular chemists due to their adaptive guest-binding properties and enzyme-like catalytic functions. We report here the adaptive self-assembly and host-guest catalysis of a new water-soluble organo-palladium host (Pd L ) built from a pyridinium-bonded macrocyclic ligand (L) and cis-blocked palladium corners (Pd). While the direct self-assembly of L with Pd gives rise to a dynamic mixture of products, both neutral polyaromatic hydrocarbons and an anionic polyoxometalate cluster (W O ) can template the dominant formation of the Pd L host.

Shape Complementary Coordination Self-Assembly of a Redox-Active Heteroleptic Complex.

We present here the coordination self-assembly of a new heteroleptic coordination complex () from one novel pyridinium-functionalized bis-2,4,6-tris(pyridin-3-yl)-1,3,5-triazine (bis-3-TPT, ) macrocyclic ligand, two separate 3-TPT () ligands, and four -blocking bpyPd(NO) (bpy = 2,2'-bipyridine). While homoleptic self-assemblies with either or gave dynamic mixtures of products, a single thermodynamic heteroleptic complex was obtained driven by the shape complementarity of building blocks. Moreover, the redox-active nature of the heteroleptic assembly facilitates the highly efficient catalytic aerobic photo-oxidation of aromatic secondary alcohols under mild conditions.

Lanthanide-organic pincer hosts with allosteric-controlled metal ion binding specificity.

A series of lanthanide-organic pincer hosts were synthesized, which showed allosteric-controlled metal ion binding selectivities due to the lanthanide-induced subtle changes of the central vacant binding site.

Mesoporous silica nanoparticle-embedded lanthanide organic polyhedra for enhanced stability, luminescence and cell imaging.

We report here a simple but efficient "ship-in-a-bottle" synthetic strategy for increasing the stability and luminescence performance of LOPs by embedding them into mesoporous silica nanoparticles (MSNs). Three types of hybrid materials, EuL@MSNs, EuL@MSNs-NH and EuL@MSNs-biotin, have been prepared and characterized by FT-IR, TGA, SEM and TEM. Photo-optical measurements confirmed that the photoluminescence quantum yields in water have been greatly improved from 5.

Guest-Driven Self-Assembly and Chiral Induction of Photofunctional Lanthanide Tetrahedral Cages.

Chiral luminescent lanthanide-organic cages have many potential applications in enantioselective recognition, sensing, and asymmetric catalysis. However, due to the paucity of structures and their limited cavities, host-guest chemistry with lanthanide-organic cages has remained elusive so far. Herein, we report a guest-driven self-assembly and chiral induction approach for the construction of otherwise inaccessible LnL-type (Ln = lanthanide ions, i.