Publications by authors named "Lior Kashani Ligumsky"

Article Synopsis
  • This study investigated if pregnant women with "flat" oral glucose tolerance test (OGTT) curves are at higher risk for bad outcomes for themselves or their babies.
  • It compared the outcomes of 1,060 women with flat OGTT curves to 10,591 with normal curves, focusing on issues like birth weight and delivery complications.
  • Results showed women with flat curves were generally younger and had a lower risk of having larger babies and needing unplanned cesarean sections, but there was no significant difference in overall adverse outcomes for mothers or newborns.
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Article Synopsis
  • * The study aimed to see how the number of pregnancies (parity) impacts the rate of spontaneous late preterm births (SLPTB) and related complications among different groups of mothers.
  • * Findings showed that first-time mothers (primiparas) have a higher risk of SLPTB and related complications compared to those with previous births (multiparas), indicating that more pregnancies may lead to better outcomes.
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Objective: To compare the efficacy and safety of cervical ripening and induction of labor with prostaglandin E1 among primiparas, multiparas and grand multiparas.

Study Design: This was a retrospective cohort study.

Results: Between January and December 2017, 1713 women underwent cervical ripening and induction of labor with prostaglandin E1: 523 were primiparas, 656 were multiparas, and 534 were grand multiparas.

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The decision to postpone parenting has gained momentum in recent years, a shift driven by evolving social dynamics and improved access to fertility treatments. Despite their increasing prevalence, pregnancies at advanced maternal ages are associated with increased risks of adverse maternal and neonatal outcomes. This article addresses the association between advanced maternal age and hypertensive disorders of pregnancies (HDPs), which are more prevalent and a significant cause of maternal morbidity and mortality in this population.

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Objective: This study aimed to determine whether a trial of labor after two cesarean deliveries (TOLAC2) increases the risk of adverse maternal and neonatal outcomes and identify prognostic factors for TOLAC2 success.

Study Design: A retrospective cohort study was conducted at a single medical center. The study group was comprised of women with a history of TOLAC2.

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Objective: To determine and compare the safety and efficacy of different methods of induction of labor in twin gestations and their effect on maternal and neonatal outcomes.

Methods: A retrospective observational cohort study was conducted at a single university-affiliated medical center. Patients with a twin gestation undergoing induction of labor at >32 + 0 weeks comprised the study group.

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Article Synopsis
  • The study examined the impact of maternal parity on complications during twin deliveries, comparing outcomes among primiparas (first-time mothers), multiparas (mothers with 1-4 previous births), and grand multiparas (mothers with 5 or more previous births) over a 6-year period.
  • Findings showed that primiparas had a significantly higher rate of maternal complications, requiring more blood transfusions and experiencing worse composite outcomes compared to multiparas and grand multiparas.
  • Additionally, primiparas delivered at an earlier gestational age and had a higher incidence of preterm labor compared to the other groups, although the mode of delivery and time interval between twins were generally similar across all parity
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Article Synopsis
  • The study aimed to evaluate the safety of vaginal delivery for a non-vertex second twin when the first twin is in a vertex position.* -
  • Researchers analyzed a cohort of 685 women with twin pregnancies, comparing outcomes between those with vertex/vertex twins and those with a vertex/non-vertex configuration.* -
  • Findings showed no significant differences in maternal and neonatal outcomes, suggesting that vaginal delivery of a breech second twin is as safe as a vertex/vertex delivery.*
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Objective: We compared neonatal immunity after vaccination against SARS-CoV-2 during pregnancy to that achieved after maternal infection.

Study Design: We tested cord blood from women infected with SARS-CoV-2 during pregnancy (group 1, n = 29), women who were vaccinated during pregnancy (group 2, n = 29) and from women not infected and not vaccinated (Group 3, n = 21) for titers of antibodies to both SARS-CoV-2 spike and 'N' proteins.

Results: Seventy-nine women were included: Antibodies against SARS-CoV-2 spike protein were detected in all samples from Group 1 and 2.

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Background: There is limited data regarding the safety of vaginal delivery in women infected with COVID-19. Our goal was to assess the safety of vaginal delivery in women infected with COVID-19 and the risk of neonatal infection.

Methods: This was a single medical center cohort study.

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