Publications by authors named "Lionel Raphael Chen"
Background: Natural orifice specimen extraction (NOSE) the anus or vagina replaces conventional transabdominal specimen retrieval the transabdominal route through a limited mid-line laparotomy or Pfannenstiel incision. Reducing the number of laparoscopic ports further decreases operative abdominal wall trauma. These techniques reduce the surgical wound size as well as the risk of incision-related morbidity.
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- The study investigates the time-dependent effects of prognostic factors on survival in patients undergoing liver resection for colorectal liver metastases (CLM), challenging the common assumption of proportional hazards in Cox models.
- Researchers analyzed data from 318 patients and found that the significance and impact of certain factors, such as tumor grade and tumor location, changed over time post-surgery.
- The results suggest that both primary tumor sidedness and grade have varying prognostic effects, indicating the need for more nuanced survival modeling in cancer research.