Publications by authors named "Lion F"

Article Synopsis
  • Conventional in-situ hydrocarbon remediation technologies struggle with high costs and limited effectiveness, making aqueous foam injection a more promising solution for better volumetric sweeping efficiency.
  • This study focuses on polymer-enhanced foams (PEFs), specifically examining how Xanthan Gum (XG) biopolymer affects foam stability and flow in contaminated soils, using two types of PEFs: one based on Sodium Dodecyl Sulfate (SDS) and another blending SDS with Cocamidopropyl Hydroxysultane (SC).
  • Results show that XG enhances foam stability through increased viscosity and improved interactions with surfactants, leading to higher recovery rates of hydrocarbons compared to traditional methods, suggesting a valuable avenue for future remediation efforts
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Article Synopsis
  • Remediation of PFAS-contaminated soils is complex because of PFAS compounds' distinct properties, like variable solubility and resistance to breakdown.
  • Using non-Newtonian fluids, like an ethanol/xanthan mixture (XE), can enhance the efficiency of in-situ soil flushing for these contaminants.
  • Lab tests showed that XE significantly improved recovery rates of PFAS, with over 99% recovery for most compounds, demonstrating the potential of this method for treating contaminated soils.
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Aqueous foam injection is a promising technique for in-situ remediation of soil and aquifers contaminated by petroleum products. However, the application efficiency is strongly hindered by foam's instability upon contact with hydrocarbons. Addressing this, we propose a new binary surfactant mixture of Sodium Dodecyl Sulfate (SDS) and Cocamidopropyl Hydroxysultaine (CAHS).

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Background: Real-world data (RWD) related to the health status and care of cancer patients reflect the ongoing medical practice, and their analysis yields essential real-world evidence. Advanced information technologies are vital for their collection, qualification, and reuse in research projects.

Methods: UNICANCER, the French federation of comprehensive cancer centres, has innovated a unique research network: Consore.

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Although polymer-surfactant injection is an effective remediation technology for multilayer aquifers contaminated by Dense Non-Aqueous Phase Liquids (DNAPL), the existence of residual DNAPL after treatment is inevitable. This study evaluates the efficiency of the post-injection of alcohol-surfactant-polymer (ASP) mixtures containing 1-propanol/1-hexanol, sodium dodecylbenzenesulfonate (SDBS), and xanthan in enhancing remediation of residual DNAPL in layered systems. A range of experimental devices, including batch, rheological measurements, centimetric 1D column, and decametric 2D tank experiments, were employed.

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To assess the efficiency of remediating dense non-aqueous phase liquids (DNAPLs), here heavy chlorinated solvents, through injection of xanthan solutions with or without surfactant (sodium dodecylbenzenesulfonate: SDBS), we conducted a comprehensive investigation involving rheological measurements, column (1D) and two-dimensional (2D) sandbox experiments, as well as numerical simulations on two-layers sand packs. Sand packs with grain sizes of 0.2-0.

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Light Non-Aqueous Phase Liquid (LNAPL) flow on the water table is highly mobile and is sensitive to the fluctuation of groundwater. This process is highly complex and involves the migration of three immiscible phases (i.e.

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Importance: Continuous kidney replacement therapy (CKRT) is the preferred method of kidney support for children with critical illness in pediatric intensive care units (PICUs). However, there are no data on the current CKRT management practices in European PICUs.

Objective: To describe current CKRT practices across European PICUs.

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Nowadays the remediation of DNAPL contaminated zones near groundwater has gained great prominence in environmental fields due to the high importance of water resources. In this work, we suggest injecting a densified polymer suspension by adding barite particles to displace DNAPL. To evaluate the efficiency of the densification of polymer suspensions on the displacement of DNAPL, various densities of barite-polymer suspension; lower, equal, and higher than the density of DNAPL were prepared and their rheological behavior was analyzed.

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Volatile pollutants from former industrial sites can degrade the buildings' indoor air quality that were built after the industrial activities. Since 2010, environmental assessments have been conducted in French establishments hosting sensitive populations identified as being on or near potentially contaminated former industrial sites. These projects are based on historical studies traditionally carried out as part of managing contaminated sites, to determine which substances should be analyzed.

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Article Synopsis
  • Early discontinuation in early-phase oncology trials impacts over one third of patients and complicates study timelines and costs; the research aims to predict successful completion of screening and dose-limiting toxicity periods using automated report analysis.
  • A machine learning model was developed using a large dataset of consultation reports to predict patient outcomes, achieving solid performance metrics (F1 score 0.80, recall 0.81) and demonstrating potential to significantly reduce screening failure rates from 39.8% to 12.8%.
  • The study highlights the importance of using machine learning with semantic analysis as a promising approach for improving patient selection in clinical trials, focusing on key terms related to disease characteristics and laboratory findings
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Purpose: Many institutions throughout the world have launched precision medicine initiatives in oncology, and a large amount of clinical and genomic data is being produced. Although there have been attempts at data sharing with the community, initiatives are still limited. In this context, a French task force composed of Integrated Cancer Research Sites (SIRICs), comprehensive cancer centers from the Unicancer network (one of Europe's largest cancer research organization), and university hospitals launched an initiative to improve and accelerate retrospective and prospective clinical and genomic data sharing in oncology.

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Pumping experiments were performed in a 2D tank in order to estimate the recovery yield of pure heavy chlorinated organic compounds (DNAPL; dense non-aqueous phase liquids) by varying different parameters: permeability of the saturated zone, pumping flow rates, addition of surfactant and heating. Surfactant was added to decrease capillary forces involved in the entrapment of DNAPL in porous media while temperature was increased to reduce DNAPL viscosity (and hence increase its mobility). Chemical enhancement was performed with the addition of Sodium Dodecyl Benzene Sulfonate (SDBS) (at its Critical Micelle Concentration, to avoid DNAPL dissolution) and thermal enhancement was performed at 50 °C (to avoid DNAPL volatilization).

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Purpose: Bereavement research has helped to improve end-of-life practices in the ICU. However, few studies have explored bereaved relatives experience of research participation in this context. We aimed to explore the experience of bereaved relatives' participation in the ARREVE study which included three telephone follow-up calls to complete several quantitative tools.

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Article Synopsis
  • The case details a rare incidence of mediastinitis that became superinfected with Achromobacter xylosoxidans after a patient underwent mitral and aortic valve replacement.* -
  • Initially, the patient developed mediastinitis caused by Staphylococcus aureus, which was treated with antibiotics; however, Achromobacter xylosoxidans was later discovered during pus analysis.* -
  • Despite initial control of the Staphylococcus aureus infection, the patient's condition worsened when blood cultures showed Achromobacter xylosoxidans again, ultimately leading to septic shock and death.*
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Purpose: The relative merits of immediate extubation versus terminal weaning for mechanical ventilation withdrawal are controversial, particularly regarding the experience of patients and relatives.

Methods: This prospective observational multicentre study (ARREVE) was done in 43 French ICUs to compare terminal weaning and immediate extubation, as chosen by the ICU team. Terminal weaning was a gradual decrease in the amount of ventilatory assistance and immediate extubation was extubation without any previous decrease in ventilatory assistance.

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Purpose: Terminal extubation (TE) and terminal weaning (TW) are the methods available for withdrawing mechanical ventilation. Perceptions of TE and TW by intensive care unit (ICU) staff may influence bedside practices and the feasibility of studies comparing these methods.

Methods: From January to June 2013, 5 nurses and 5 physicians in each of 46 (out of 70, 65.

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Background: The aim was to describe a strategy for recruitment of healthy volunteers (HV) to a randomized trial that assessed the efficacy of different telephone techniques to assist HV in performing cardiac massage for vital emergency. Participation in the randomized trial was not financially compensated, however HV were offered emergency first-aid training. We also studied factors associated with HV motivation and satisfaction regarding participation in the trial.

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The authors describe three cases of severe accidental poisoning by plants used as part of a traditional treatment in Mayotte. The established, or suspected, toxicity of Thevetia peruviana (Yellow oleander), Cinchona pubescens (Red quinine-tree), Melia azaderach (Persian lilac, also called china berry) and Azadirachta indica (Neem), is discussed. The clinical presentation is cardiac (atrioventricular block) and well known for Thevetia and Cinchona intoxications.

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Background: Acute renal dysfunction (ARD) is common after cardiac surgery with cardiopulmonary bypass (CPB). CPB results in a sudden systemic inflammatory response. Systemic and local pro-inflammatory cytokines synthesis has been linked with sub-clinical renal injury, especially tubular lesions.

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Objectives: Pulmonary oedema in self-contained underwater breathing apparatus diving is an accident whose risk factors, conditions of occurrence and incidence are not well-known. The aim of this study was to evaluate the frequency, the risk factors and the evolution of this accident.

Study Design: Retrospective case study and prospective frequency study.

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We evaluated the results of using extracorporeal membrane oxygenation (ECMO) as resuscitation for cardiac patients undergoing cardiopulmonary resuscitation (CPR) in our setting where neither perfusionists nor surgeons are always on site, and no circuit may be ready. Between 2003 and 2006, we used ECMO for all cardiac patients who underwent cardiac arrest in the pediatric intensive care unit (PICU) or Cath Laboratory. We reviewed retrospectively 14 consecutive files (15 episodes).

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