Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury.

Flap transplantation is a critical part of the recovery process for patients who have undergone tumor resection. However, the process of ischemia-reperfusion injury during flap transplantation and the resulting high-risk thrombotic microenvironment are unavoidable. In this study, based on an in-depth investigation of the ischemia time and prognosis of transplanted flaps, we propose a treatment strategy using sequential thrombolysis and ischemia-reperfusion injury prevention tailored to the ischemia time.

 (Primulaceae), a new species from Yunnan, China.

A new species, , is described and illustrated. In gross morphology, it is clearly allied to section Petiolares and is most similar to from the group , but is distinctive in its indumentum in the throat of the corolla tube, and the markedly stoloniferous habit.