Publications by authors named "Linzhao He"

Article Synopsis
  • * In experiments with Caenorhabditis elegans, BMS improved movement, reduced muscle damage due to aging, and decreased reactive oxygen species (ROS) accumulation while enhancing the activity of key antioxidant enzymes (SOD and CAT).
  • * The study suggests that BMS influences lifespan extension through the insulin/insulin-like growth factor-1 signaling (IIS) pathway, involving factors like sir-2.1 and hlh-30, highlighting BMS as a promising candidate for anti-aging functional foods.
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Saponins from bitter melon (BMS) are well-known to have various biological activities, especially in the field of fat-lowering. However, many gaps remain in our knowledge of BMS-induced fat reduction and health benefits. Here, we aimed to investigate the precise mechanism of BMS in alleviating fat accumulation in and HepG2 cell line.

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