Publications by authors named "Linyuan Pan"

Article Synopsis
  • The study investigates the effectiveness of two surgical techniques for medial patellofemoral ligament reconstruction (MPFLR) in patients with patellar dislocation, comparing non-absorbable sutures (FiberWire) and semitendinosus tendon grafts.
  • It's a randomized controlled trial involving 30 participants, divided into two groups, with assessments for pain, knee function, and quality of life at multiple time points post-surgery.
  • The trial has ethical approval and intends to publish its findings in peer-reviewed journals, aiming to contribute to better surgical practices in orthopedics.
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Purpose: To evaluate the postoperative outcomes of the all-inside technique in arthroscopic anterior cruciate ligament reconstruction (ACLR).

Methods: Patients who underwent ACLR using the all-inside technique between 2018 and 2021 were retrospectively assessed. All patients were followed up for at least 2 years.

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Background: An umbrella review was conducted to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus non-ESWT in the treatment of knee osteoarthritis (KOA).

Materials And Methods: Three databases including PubMed, Embase and Web of science were searched up to September 2023. Literature screening, quality evaluation, and data extraction were performed according to inclusion and exclusion criteria.

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Introduction: Anterior cruciate ligament (ACL) rupture is one of the most common knee injuries in sports, and the gold standard for treating ACL rupture is tendon graft reconstruction. Internal brace technology is being used nowadays for ligament repair; however, more relevant in vivo clinical evidence is required for using internal brace technology in ACL reconstruction (ACLR). We conducted a randomised controlled trial to investigate the clinical efficacy of internal brace technology in ACLR.

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Meniscus suture is an important treatment method for meniscus injury and contributes to the preservation of proprioception, restoration of knee biomechanics and alleviation of progressive osteoarthritis. However, there are few visualized analyses concerning the present studies of meniscus suture. This paper aims to evaluate the global trends, highlights and frontiers of meniscus suture.

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Background: Ferroptosis was proposed to be a type of programmed cell death in 2012. Ferroptosis plays a significant role in a variety of illnesses.

Objective: To better understand the direction of future research, we performed a bibliometric analysis to identify research hotspots with a focus on ferroptosis.

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Acute septic arthritis is on the rise among all patients. Acute septic arthritis must be extensively assessed, identified, and treated to prevent fatal consequences. Antimicrobial therapy administered intravenously has long been considered the gold standard for treating acute osteoarticular infections.

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Objectives: To determine whether dual-energy CT (DECT) can be used to accurately and reliably detect anterior cruciate ligament (ACL) rupture.

Materials And Methods: Participants with unilateral ACL rupture were prospectively enrolled, and the bilateral knees were scanned by DECT. A tissue-specific mapping algorithm was applied to improve the visualization of the ACLs.

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Purpose: Our purpose was to assess job stress and burnout among anesthesiologists in the tertiary class A hospitals in Northwest China, analyze the possible causes and adverse consequences of increased job stress and burnout of anesthesiologists in this region, and put forward suggestions in combination with the current national policies.

Methods: We sent 500 electronic questionnaires to all anesthesiologists practicing in the tertiary class A hospitals in Northwest China from 1960 to 2017 on April 2020. A total of 336 (67.

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Background: Currently, there are many surgical options for patellar dislocation. The purpose of this study is to perform a network meta-analysis of the randomized controlled trials (RCTs) and cohort studies to determine the better treatment.

Method: We searched the Pubmed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, clinicaltrials.

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Article Synopsis
  • The study aimed to evaluate the impact of local infiltration anesthesia (LIA) combined with femoral nerve block (FNB) on early postoperative pain and rehabilitation after ACL reconstruction in 73 patients, divided into two groups.
  • Group A received LIA at the hamstring donor site, while Group B received saline; pain levels, opioid use, and knee function scores were assessed pre- and post-surgery.
  • Results showed that LIA reduced early postoperative pain and opioid consumption, but there were no significant differences in pain intensity or functional outcomes between the groups at later assessments.
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Purpose: To evaluate the extent of tunnel widening after anterior cruciate ligament reconstruction (ACLR) using the all-inside technique and to establish its correlation with patient-reported clinical outcomes and femoral graft bending angle (GBA).

Methods: Tunnel widening was evaluated using computed tomography (CT)-based three-dimensional (3D) models, and the femoral GBA was directly measured on CT images using the Picture Archiving and Communication System (PACS) software. Clinical follow-up was routine procedure, and patient-reported clinical outcomes mainly included International Knee Documentation Committee (IKDC), Lysholm, and Knee Injury and Osteoarthritis Outcome Scores (KOOS) scores, and subjective knee stability assessment.

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Article Synopsis
  • - Osteoarthritis (OA) is a widespread health issue with unclear causes, and there are currently no effective drugs that modify the disease; exosomes play a crucial role in its pathophysiology by influencing inflammation and cartilage degradation.
  • - Exosomes are small vesicles that carry proteins, RNAs, and other molecules, which can be found in synovial fluid and plasma, and their levels change as OA progresses, indicating potential as diagnostic biomarkers.
  • - Exosomes from mesenchymal stem cells show promise for therapeutic use in OA by promoting cartilage restoration and balancing inflammatory processes, especially when combined with materials like hydrogels for tissue engineering.
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Sarcopenia is an age-related disease in which muscle mass, strength and function may decline with age or can be secondary to cachexia or malnutrition and can lead to weakness, falls and even death. With the increase in life expectancy, sarcopenia has become a major threat to the health of the elderly. Currently, our understanding of bone-muscle interactions is not limited to their mechanical coupling.

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Sarcopenia is an aged-related syndrome that is progressive and can be accelerated by other concomitant disease states. Sarcopenia, characterized by loss of skeletal muscle mass, reduced muscle strength, and/or reduced physical performance, is one of the main reasons for limitation of daily activities in the elderly. It is associated with an increased incidence of many adverse events, such as dysfunction, falls, weakness, hospitalization, disability and even death.

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