Publications by authors named "Linxian Cheng"
The tubuli recti (TR) are immunologically special, because the lymphocytes preferably accumulate around them during the course of T-cell dependent testicular autoimmunity in mice. This finding implies that the testicular interstitium around the TR is where autoreactive lymphocytes can gain access to autoimmunogenic germ cell antigens. In the present study, the histoarchitecture of the TR was minutely examined in normal mice.
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- The study investigates the effects of di-(2-ethylhexyl) phthalate (DEHP) on male ICR mice, particularly focusing on the testes, liver, kidneys, and pancreas after 10 days of exposure to a 2% DEHP diet.
- Results demonstrated severe damage to spermatogenesis and liver function, with high levels of nitrogen oxides and lipid peroxidation detected in the testes, indicating stress from free radicals.
- The findings suggest that the detrimental effects on sperm production are due to the sensitivity of testicular tissues to mono-(2-ethylhexyl) phthalate (MEHP), not its accumulation in the testes.