A new classification for surgical NEC during exploratory laparotomy: introduction and reproducibility assessment.

Purpose: Variability in necrosis patterns and operative techniques in surgical necrotizing enterocolitis (NEC) necessitates a standardized classification system for consistent assessment and comparison. This study introduces a novel intraoperative reporting system for surgical NEC, focusing on reliability and reproducibility.

Methods: Analyzing surgical NEC cases from January 2018 to June 2023 at two tertiary neonatal and pediatric surgery units, a new classification system incorporating anatomical details and intestinal involvement extent was developed.

Efficacy of Targeted Scapular Stabilization Exercise Versus Conventional Exercise for Patients With Shoulder Pain: A Randomized Clinical Trial.

Objective: The aim of the study is to investigate the efficacy of targeted scapular stabilization exercise in shoulder pain.

Design: This is an evaluator-blinded, multicenter, randomized controlled trial. The scapular stabilization exercise group ( n = 45) received scapular stabilization exercise based on the type of scapular dyskinesis for 6 wks; the conventional exercise group ( n = 45) received pendulum, wall climbing and stick exercises for 6 wks.

Neurodevelopmental impairment following surgical necrotizing enterocolitis with gestational age ≥ 28 weeks: who is at risk?

Purpose: Surgical necrotizing enterocolitis (NEC) is a severe medical condition that, even after surgery, a portion of the survival infants may still have neurological sequelae. The objective of this study was to identify the risk factors associated with the development of permanent neurodevelopmental impairment (NDI) in neonates with surgical NEC.

Methods: Between January 2016 and June 2022, a retrospective data collection was conducted on 98 individuals who experienced surgical NEC with gestational age ≥ 28 weeks.

Insights into the multi-functional lithium difluoro(oxalate)borate additive in boosting the Li-ion reaction kinetics for LiVO anodes.

The rational design of a solid electrolyte interphase (SEI) with high ionic conductivity and high electrochemical stability is significantly important in improving the electrochemical performance of anode materials. Herein, lithium difluoro(oxalate)borate (LiDFOB) is used as an electrolyte additive to generate protective SEI films on LiVO (LVO) anodes. The addition of LiDFOB is beneficial to form a dense, uniform, stable and LiF-richer SEI, which is helpful to boost the Li-ion storage kinetics.

Optimizing water and nitrogen management strategies to improve their use efficiency, eggplant yield and fruit quality.

With improvement in living standards, consumer preferences for vegetables are changing from quantity- to quality-oriented. Water and nitrogen supply, as two major determinants of vegetable crop yield and quality, can be optimally managed to improve the yield and quality. To evaluate the response in yield, fruit quality, and water and nitrogen utilization of eggplant to different water and nitrogen management strategies, a 2-year (2021 and 2022) field trial under mulched drip irrigation was conducted.

Spatiotemporal heterogeneity correction in land ecosystem services and its value assessment: a case study of the Loess Plateau of China.

The considerable variation in structures and functions of different ecosystems leads to highly variable ecosystem service values (ESVs). Consequently, the accurate quantification of ESVs can better assess and reflect impacts of land use and cover changes (LUCC) on ecosystem services. In the land use simulations of this study, a CA-Markov model was chosen and nine factors affecting land use change were evaluated, followed by the construction of a multi-criteria evaluation method to simulate land use scenarios between 2025 and 2030 on the Loess Plateau.

Analysis of Land Use Change Drivers and Simulation of Different Future Scenarios: Taking Shanxi Province of China as an Example.

This study analyzed change and spatial patterns of land use in Shanxi from 2000 to 2020. The drivers of land use and cover change (LUCC) in cultivated lands, forest lands, grasslands, and rural construction areas were explored from four dimensions, including population, natural environment, location traffic, and economic development. The CA-Markov model was used to simulate the scenarios of natural growth (NG), ecological protection (EP), economic development (ED), food security (FS), ecological protection-economic development (EP-ED), and ecological protection-food security (EP-FS) in 2030.

Surgical Treatment of Adams Type IV Anterolateral Fracture of the Ulna Coronoid Process.

Objective: Anterolateral coronal fractures are so rare that the mechanism of injury, the type of combined fracture and ligament injury, and the optimal treatment are unknown. To study the outcome of surgical treatments for anterolateral (AL) fracture of the ulna coronoid process (Adams Type IV) and summarize the characteristics of this type of fracture and to guide clinical applications.

Methods: From February 2015 to April 2021, 32 patients were included in the study.

Astaxanthin Induces Apoptosis in Human Osteosarcoma MG-63 Cells.

We explored the mechanism of human osteosarcoma MG-63 cell apoptosis induced by asta-xanthin. The MTT assay was used to detect the effect of astaxanthin on cell viability. Morphological changes associated with apoptosis were observed after DAPI staining.

Study on the CHZ-II Gravimeter and Its Calibrations along Forward and Reverse Overlapping Survey Lines.

The moving-base gravimeter is one of the key instruments used for Earth gravity survey. The accuracy of the survey data is closely related to the calibration precision of several key parameters, such as the damping delay time, the drift coefficient, the gravity scale factor, and the measurement accuracy. This paper will introduce the development of the CHZ-II gravimeter system in which a cylindrical sampling mass suspended vertically by a zero-length spring acts as a sensitive probe to measure specific force.

Unusual Spreading of Strain Neutral Layer in AZ31 Magnesium Alloy Sheet during Bending.

In this work, we reported an unusual phenomenon of strain neutral layer (SNL) spreading in an as-rolled AZ31B magnesium alloy sheet during V-bending. The SNL on the middle symmetrical surface perpendicular to the transverse direction (TD) of the sheet extended to the compression region and was accompanied by a mound-like feature. However, the SNL on the side surface perpendicular to the TD was distributed with a parallel band feature.

Nattokinase enhances the preventive effects of Escherichia coli Nissle 1917 on dextran sulfate sodium-induced colitis in mice.

Nattokinase with excellent anti-thrombotic, anti-inflammatory, anti-tumor, and anti-hypertension properties has been used in the development of several healthcare products in many countries. The probiotic Escherichia coli Nissle 1917 (EcN) with anti-inflammatory effect is commonly used to treat inflammatory bowel disease. To determine whether nattokinase could enhance the therapeutic efficacy of EcN in colitis, a recombinant E.

Massive gastrointestinal haemorrhage caused by pancreatic pseudocyst complicated with Dieulafoy's disease in a child: A case report and review of the literature.

Background: Pancreatic pseudocyst (PPC) with massive gastrointestinal bleeding is rare, especially in children. Inadvertent intraoperative examination and damage to the gastric mucosa and malformed blood vessels by the fluid content of PPC can lead to massive bleeding, which may endanger the patient's life.

Case Presentation: Here, we present a case of an 8-year-old boy who was diagnosed with a massive gastrointestinal haemorrhage caused by PPC complicated with Dieulafoy's disease.

Oridonin attenuates dextran sulfate sodium‑induced ulcerative colitis in mice via the Sirt1/NF‑κB/p53 pathway.

Ulcerative colitis (UC) is a serious chronic inflammatory bowel disease. Oridonin (Ori) has anti‑inflammatory, antibacterial and antitumor activities. The current study aimed to investigate the regulatory role of Ori in UC.

CTTGAN: Traffic Data Synthesizing Scheme Based on Conditional GAN.

Most machine learning algorithms only have a good recognition rate on balanced datasets. However, in the field of malicious traffic identification, benign traffic on the network is far greater than malicious traffic, and the network traffic dataset is imbalanced, which makes the algorithm have a low identification rate for small categories of malicious traffic samples. This paper presents a traffic sample synthesizing model named Conditional Tabular Traffic Generative Adversarial Network (CTTGAN), which uses a Conditional Tabular Generative Adversarial Network (CTGAN) algorithm to expand the small category traffic samples and balance the dataset in order to improve the malicious traffic identification rate.

Development and immunogenicity evaluation of porcine deltacoronavirus inactivated vaccine with different adjuvants in mice.

Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in pigs of various ages, especially in suckling piglets, and there are no effective measures to prevent and control PDCoV currently. In this study, two adjuvants Al(OH) and ODN2395 working through different mechanisms were used to prepare inactivated PDCoV vaccines, and the immune effects of PDCoV inactivated vaccines were assessed in mice. From the results, we found that both PDCoV/Al(OH) vaccine and PDCoV/2395 vaccine could induce IgG and neutralizing antibodies with high levels in mice.

Multi-Hierarchical Fusion to Capture the Latent Invariance for Calibration-Free Brain-Computer Interfaces.

Brain-computer interfaces (BCI) based motor imagery (MI) has become a research hotspot for establishing a flexible communication channel for patients with apoplexy or degenerative pathologies. Accurate decoding of motor imagery electroencephalography (MI-EEG) signals, while essential for effective BCI systems, is still challenging due to the significant noise inherent in the EEG signals and the lack of informative correlation between the signals and brain activities. The application of deep learning for EEG feature representation has been rarely investigated, nevertheless bringing improvements to the performance of motor imagery classification.

Meaningful Secret Image Sharing with Saliency Detection.

Secret image sharing (SIS), as one of the applications of information theory in information security protection, has been widely used in many areas, such as blockchain, identity authentication and distributed cloud storage. In traditional secret image sharing schemes, noise-like shadows introduce difficulties into shadow management and increase the risk of attacks. Meaningful secret image sharing is thus proposed to solve these problems.

Identification of two novel B-cell epitopes on the nucleocapsid protein of porcine deltacoronavirus.

• Two monoclonal antibodies against newly emerged porcine deltacoronavirus nucleocapsid protein were prepared. • The epitopes that these two monoclonal antibodies recognized on nucleocapsid protein were identified. • The monoclonal antibody 6B7 recognized a linear epitope of N protein, while the 7F8 recognized a conformational epitope.

A Five-Gene Risk Score Model for Predicting the Prognosis of Multiple Myeloma Patients Based on Gene Expression Profiles.

Multiple myeloma is a heterogeneous plasma cell malignancy that remains incurable because of the tendency of relapse for most patients. Survival outcomes may vary widely due to patient and disease variables; therefore, it is necessary to establish a more accurate prognostic model to improve prognostic precision and guide clinical therapy. Here, we developed a risk score model based on myeloma gene expression profiles from three independent datasets: GSE6477, GSE13591, and GSE24080.

Evaluation of the Effect of Inactivated Transmissible Gastroenteritis Virus Vaccine with Nano Silicon on the Phenotype and Function of Porcine Dendritic Cells.

A transmissible gastroenteritis virus (TGEV) is a porcine enteropathogenic coronavirus, causing acute swine enteric disease especially in suckling piglets. Mesoporous silica nanoparticles (MSNs) are safe vaccine adjuvant, which could enhance immune responses. Our previous research confirmed that nano silicon had immune-enhancing effects with inactivated TGEV vaccine.

RARγ activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway.

Proteasome inhibitors (PIs) such as bortezomib (Btz) and carfilzomib (Cfz) are highly efficacious for patients with multiple myeloma (MM). However, relapses are frequent, and acquired resistance to PI treatment emerges in most patients. Here, we performed a high-throughput screen of 1855 Food and Drug Administration (FDA)-approved drugs and identified all-trans retinoic acid (ATRA), which alone has no antimyeloma effect, as a potent drug that enhanced MM sensitivity to Cfz-induced cytotoxicity and resensitized Cfz-resistant MM cells to Cfz in vitro.

Potato growth, photosynthesis, yield, and quality response to regulated deficit drip irrigation under film mulching in a cold and arid environment.

The effects of the amount and timing of regulated deficit drip irrigation under plastic film on potato ('Qingshu 168') growth, photosynthesis, yield, water use efficiency, and quality were examined from 2017 to 2019 in cold and arid northwestern China. In the four stages of potato growth (seedling, tuber initiation, tuber bulking, starch accumulation), eight treatments were designed, with a mild deficit was in treatments WD1 (seedling), WD2 (tuber initiation), WD3 (tuber bulking), and WD4 (starch accumulation); and a moderate deficit in WD5 (seedling), WD6 (tuber initiation), WD7 (tuber bulking), and WD8 (starch accumulation). The net photosynthetic rate, stomatal conductance, and transpiration rate decreased significantly under water deficit in the tuber formation and starch accumulation stages.

CD36-mediated ferroptosis dampens intratumoral CD8 T cell effector function and impairs their antitumor ability.

Understanding the mechanisms underlying how T cells become dysfunctional in a tumor microenvironment (TME) will greatly benefit cancer immunotherapy. We found that increased CD36 expression in tumor-infiltrating CD8 T cells, which was induced by TME cholesterol, was associated with tumor progression and poor survival in human and murine cancers. Genetic ablation of Cd36 in effector CD8 T cells exhibited increased cytotoxic cytokine production and enhanced tumor eradication.