Publications by authors named "Linsey Bui"
Article Synopsis
- - Colorectal adenocarcinoma is the most common type of colorectal cancer in the U.S., driven by genetic mutations like APC, KRAS, HER-2 IHC3+, CHEK-2, and TP53 that result in cancer development.
- - Standard treatment for metastatic colorectal cancer often includes chemotherapy and targeted therapies, but many patients endure disease progression, prompting the search for new treatments like fruquintinib, a selective VEGFR inhibitor.
- - A case report describes a patient with metastatic colorectal cancer who suffered a cerebellar hemorrhage after starting fruquintinib, emphasizing the importance of close monitoring and personalized risk assessments for patients on this medication.
Calyceal rupture, defined as the extravasation of urine from the renal calyces into the perinephric or paranephric spaces, typically results from increased intrapelvic pressure due to urinary tract obstruction. This condition can lead to the formation of a perinephric urinoma and severe complications, such as infection, abscess formation, and impaired renal function. Timely diagnosis and management are crucial to prevent these adverse outcomes.
View Article and Find Full Text PDFPneumatosis intestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially life-threatening conditions characterized by the presence of gas within the bowel wall and portal venous system, respectively. This case report presents a 45-year-old male with a history of methamphetamine use who developed severe metabolic and hemodynamic instability, marked by altered mental status, metabolic acidosis, and ST elevations. Despite aggressive resuscitation and intensive care, the patient unfortunately succumbed to his condition, highlighting the gravity of these complications.
View Article and Find Full Text PDFArticle Synopsis
- Healthspan science focuses on increasing the number of healthy years in a person's life by investigating various methods to improve overall health and longevity.
- Research has shown that returning to ancestral diets can enhance functional health in older individuals and that certain botanical extracts may significantly extend lifespan without affecting reproductive ability.
- This study explores the combined effects of an ancestral diet and botanical extracts, finding that while one extract improved health, another had negative effects when paired with the diet, highlighting the need for further research on how different healthspan interventions interact.