Detection of other pathologies when utilising computer-assisted digital solutions for TB screening.

Background: Computer-aided detection (CAD) tools for TB detection have the potential to enable screening programmes and reduce the diagnostic gap in settings where access to radiologists is limited. However, there are concerns that other common chest X-ray (CXR) abnormalities not due to TB may be missed.

Methods: We assessed the performance of three commercialised CAD tools (qXR, INSIGHT CXR and DrAID TB XR) to detect common non-TB abnormalities against readings with a standardised annotation guide by an expert radiologist.

Is the risk of chronic pain after total temporomandibular joint replacement independent of its indications? A prospective cohort study.

Chronic pain is a possible long-term complication after alloplastic temporomandibular joint reconstruction (TMJR). This study was developed to evaluate various subjective and objective measurements to determine the presence and degree of TMJ pain in patients treated with TMJR regardless of the indication for the operation. A prospective, single-centre study was performed.

A Total of 1,132 All-Ceramic Single-Tooth Restorations Show Acceptable Survival Rates up to 15 Years in a Non-University Setting.

Purpose: To evaluate the long-term survival of IPS Empress 2 and IPS e.max (Ivoclar Vivadent) restorations in a non-university setting.

Materials And Methods: A retrospective study design was used to evaluate the survival rate of 1,132 Empress 2 and IPS e.

Does Maximum Voluntary Clenching Force Pose a Risk to Overloading Alloplastic Temporomandibular Joint Replacement?-A Prospective Cohort Study.

Purpose: The amount of maximum voluntary clenching (MVC) force may influence functional loading at the polyethylene/metal bearing surfaces in alloplastic total temporomandibular joint replacement (TMJR). The aim of this study was to measure ipsilateral MVC and estimate the risk for revision due to overloading of the TMJR.

Methods: A prospective cohort study design was used to study patients who underwent alloplastic TMJR.

Unilateral, Alloplastic Temporomandibular Joint Reconstruction, Biomechanically What Happens to the Contralateral Temporomandibular Joint?-A Prospective Cohort Study.

Purpose: Unilateral alloplastic total temporomandibular joint reconstruction (TMJR) might influence the contralateral side joint function. This study's purpose was to estimate the risk for contralateral TMJR and the jaw function of the contralateral untreated temporomandibular joint (TMJ).

Patients And Methods: A prospective cohort study design was used for patients who underwent unilateral alloplastic TMJR.

How Does a Unilateral Temporomandibular Joint Replacement Affect Bilateral Masseter and Temporalis Muscle Activity?-A Prospective Study.

Purpose: Total alloplastic temporomandibular joint replacement (TMJR) requires the detachment of the masseter muscle (MM) at its insertion to the lateral ramus and often the resection of the coronoid process (insertion of the temporalis muscle). There is little literature on how a detachment affects the muscles. The present study evaluates the long-term masticatory muscle activities and maximum voluntary bite force (MVC) in patients with unilateral TMJR.

Lexicosemantic, affective, and distributional norms for 1,000 Dutch adjectives.

The research of the word is still very much the research of the noun. Adjectives have been largely overlooked, despite being the second-largest word class in many languages and serving an important communicative function, because of the rich, nuanced qualifications they afford. Adjectives are also ideally suited to study the interface between cognition and emotion, as they naturally cover the entire range of lexicosemantic variables such as imageability (infinite-green), and affective variables such as valence (sad-happy).

Age- and localization-dependent functional and psychosocial impairments and health related quality of life six months after OSCC therapy.

Objectives: The aim of the current study was to evaluate the functional and psychosocial impacts and changes in overall quality of life (QoL) following oral squamous cell carcinoma (OSCC) therapy in different age groups and in different oral locations.

Materials And Methods: The study assessed questionnaire responses from patients with OSCC (n = 1319) after 6 months of oncologic therapy, as collected in the DÖSAK Rehab Study. Oncological variables, dental status, sensory, QoL, psychosocial outcomes and coping strategies in younger (45-60 years) and older (61-100 years) patients were assessed for different OSCC locations including the entire oral cavity, maxilla, mandible and others besides the maxilla and mandible.

Mandibular kinematics and maximum voluntary bite force following segmental resection of the mandible without or with reconstruction.

Objectives: The purpose was to analyze mandibular kinematics and maximum voluntary bite force in patients following segmental resection of the mandible without and with reconstruction (autologous bone, alloplastic total temporomandibular joint replacement (TMJ TJR)).

Materials And Methods: Subjects operated from April 2002 to August 2014 were enrolled in the study. Condylar (CRoM) and incisal (InRoM) range of motion and deflection during opening, condylar retrusion, incisal lateral excursion, mandibular rotation angle during opening, and maximum voluntary bite force were determined on the non-affected site and compared between groups.

Bite force and electromyography evaluation after cranioplasty in patients with craniosynostosis.

Objective: This long-term follow-up investigation aimed to assess masticatory muscle function in 15 patients with craniosynostosis with detachment of the temporal muscle during fronto-orbital advancement 6 years after cranioplasty compared with a non-operative stomatognathic healthy cohort in the same age group (n = 25).

Study Design: The follow-up assessment for the operated children occurred on average 5.2 ± 1.

Long-term outcomes of mandibular kinematics following class II malocclusion therapy with removable functional appliance therapy.

Objective: To evaluate mandibular kinematics in class I adults following class II therapy with removable functional appliances (RFAs) during the growth period in comparison with orthodontically untreated class I and II individuals.

Methods: Condylar (CRoM) and incisal range of motion (InRoM), velocity during opening and closing, and the mandibular rotation angle were recorded using an ultrasound-based jaw-tracking system in 36 test patients (mean age = 28.03 ± 6.

The association between symbolic and nonsymbolic numerical magnitude processing and mental versus algorithmic subtraction in adults.

There are two well-known computation methods for solving multi-digit subtraction items, namely mental and algorithmic computation. It has been contended that mental and algorithmic computation differentially rely on numerical magnitude processing, an assumption that has already been examined in children, but not yet in adults. Therefore, in this study, we examined how numerical magnitude processing was associated with mental and algorithmic computation, and whether this association with numerical magnitude processing was different for mental versus algorithmic computation.

Partial depletion of yolk during zebrafish embryogenesis changes the dynamics of methionine cycle and metabolic genes.

Background: Limited nutrient availability during development is associated with metabolic diseases in adulthood. The molecular cause for these defects is unclear. Here, we investigate if transcriptional changes caused by developmental malnutrition reveal an early response that can be linked to metabolism and metabolic diseases.

The influence of different registration positions on condyle displacement in symptomatic patients.

Objective: This study aimed to evaluate effects of different registration positions on the condyle-disk position changes in the mandibular fossa in symptomatic individuals.

Study Design: Vertical and sagittal condyle position and thickness of the bilaminar zone were measured by magnetic resonance imaging during maximal intercuspation (MI) and with jigs in Gothic arch tracing guided centric relation (DIR method [Dynamics and Intraoral Registration]) and retruded contact position (RCP). Participants were 26 patients seeking treatment for temporomandibular disorders.

The association between children's numerical magnitude processing and mental multi-digit subtraction.

Children apply various strategies to mentally solve multi-digit subtraction problems and the efficient use of some of them may depend more or less on numerical magnitude processing. For example, the indirect addition strategy (solving 72-67 as "how much do I have to add up to 67 to get 72?"), which is particularly efficient when the two given numbers are close to each other, requires to determine the proximity of these two numbers, a process that may depend on numerical magnitude processing. In the present study, children completed a numerical magnitude comparison task and a number line estimation task, both in a symbolic and nonsymbolic format, to measure their numerical magnitude processing.

Reproducibility of condyle position and influence of splint therapy on different registration techniques in asymptomatic volunteers.

The current study aims to analyze and quantify the effects of different registration techniques on the reproducibility of condyle position and the influence of stabilization splint therapy on the technique's reproducibility. Three-dimensional electronic-condylar-position analysis (EPA) with an ultrasound-based jaw-tracking system was recorded during intermaxillary registration of manually guided centric relation (CR), maximal intercuspation (MI), and clenching-force-dependent Gothic arch tracing guided centric relation (DIR method) before (T0) and after (T1) splint therapy. Patients were supplied with a stabilization splint for three months on the basis of the DIR registration.

Aesthetic preference for spatial composition in multiobject pictures.

Five experiments examined preferences for horizontal positions in multiobject pictures. In Experiment 1, each picture contained a fixed object and an object whose position could be adjusted to create the most (or least) aesthetically pleasing image. Observers placed the movable object closer to the fixed object when the objects were related than when they were unrelated (a relatedness bias) but almost never overlapped them (a separation bias).

Hepatocyte-targeted delivery using ph-sensitive liposomes loaded with lactosylnorcantharidin phospholipid complex: preparation, characterization, and therapeutic evaluation in vivo and in vitro.

Liposomes loaded with lactosyl-norcantharidin phospholipid complex (LPC) were prepared, in which soybean phosphatidylcholine was used to improve the liposolubility of lactosyl-norcantharidin (Lac-NCTD). The pH-sensitive LPC liposomes (pH-LPC-lips) were obtained by electrostatic adsorption of the carboxymethyl chitosan onto the surface of the liposomes. The in vitro drug release of pH-LPC-lips and LPC-lips was investigated in dissolution media with pH ranging from 1.

Pressure pain threshold and oral health-related quality of life implications of patients with alloplastic temporomandibular joint replacement--a prospective study.

Purpose: Alloplastic total temporomandibular joint replacement (TJR) for end-stage disease, congenital disorders, and after ablative surgery has been shown improve function and to decrease pain. The purpose of this study was to evaluate the pain pressure threshold (PPT) and oral health-related quality of life (OHRQoL) in patients undergoing alloplastic TJR.

Materials And Methods: Subjects requiring TJR from May 2007 through February 2011 were enrolled in the study.

Mandibular kinematics in patients with alloplastic total temporomandibular joint replacement--a prospective study.

Purpose: The purpose was to analyze the mandibular patterns (condylar range of motion during opening; incisal range of motion during opening, lateral excursion, and protrusion; velocity during opening and closing; mandibular rotation angle during opening and closing) in patients with alloplastic total joint replacement (TJR).

Materials And Methods: Seventeen patients with different diagnoses resulting in condylar hypomobility (8 patients, 15 joints) and condylar instability (9 patients, 12 joints) had undergone alloplastic TJR. Data were recorded preoperatively and 2, 6, and at least 12 months postoperatively.

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

Background: With the advent of next generation sequencing it has become possible to detect genomic variation on a large scale. However, predicting which genomic variants are damaging to gene function remains a challenge, as knowledge of the effects of genomic variation on gene expression is still limited. Recombinant inbred panels are powerful tools to study the cis and trans effects of genetic variation on molecular phenotypes such as gene expression.

Changes in condylar position using different types of splints with and without a chinstrap: a case-control study.

The aim of this case-control study was to analyze and quantify if there is a different mechanical effect of stabilization and pivot splints with uni- or bilateral pivot of different heights and with and without an additional chinstrap, on the vertical, sagittal, and horizontal condyle position. A stabilization splint and splints with unilateral or bilateral posterior pivot support of 0.6 mm or 1.