Publications by authors named "Linqiang Gong"

Background: Acute pancreatitis (AP) is a complex inflammatory condition with rising incidence globally. Despite various known causes, early diagnosis remains challenging due to limitations in existing biomarkers. Metabolomics offers a promising avenue for identifying novel biomarkers and elucidating underlying pathophysiological mechanisms.

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  • Traumatic brain injury (TBI) disrupts brain function due to external forces, and current treatments are ineffective, leading researchers to investigate the neuroprotective effects of MOTS-c.
  • In a study using mice, it was found that MOTS-c levels were lower after TBI, but administering it improved cognitive and motor functions.
  • Through transcriptomic and metabolomic analyses, various significantly altered genes and metabolites were identified, revealing pathways that MOTS-c may influence to provide neuroprotection after TBI.
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The skeletal system is crucial for supporting bodily functions, protecting vital organs, facilitating hematopoiesis, and storing essential minerals. Skeletal homeostasis, which includes aspects such as bone density, structural integrity, and regenerative processes, is essential for normal skeletal function. Autophagy, an intricate intracellular mechanism for degrading and recycling cellular components, plays a multifaceted role in bone metabolism.

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  • Cold exposure helps improve how the body uses fat and can be good for health.
  • Scientists studied mice to see how cold affects different body tissues like fat and blood.
  • They found many important substances that changed in the mice, which could help us understand better ways to treat metabolism-related health problems.
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