Ni Vacancy and the Se/S Ratio Regulate the p-Band Center of Hollow NiSSe/Phase Junction CdS to Achieve High Efficiency and Broad-Spectrum Photocatalytic Performance.

Rational design of defect engineering and interfacial built-in electric fields of photocatalysts is imperative for renewable energy conversion. Herein, a multi-strategy involving the introduction of Ni vacancies, the adjustment of the Se/S ratio, and the construction of dual junctions are employed to simultaneously realize NiSSe/phase junction CdS (HCC) an excellent photocatalytic activity and broad light absorption. With the help of V and the regulation of S/Se, the local electrons are redistributed to occupy more antibonding orbitals and adjust the p-band center, thus optimizing the H adsorption energy of the catalyst to accelerate the photocatalytic reaction kinetics.

Hollow cubic CuSe@CdS with tunable size for plasmon-induced Vis-NIR driven photocatalytic properties.

The rational design of the dimension and geometry of a plasmonic semiconductor cocatalyst is vitally important for efficient utilization of near-infrared (NIR) light and superior photocatalytic hydrogen generation. Herein, hollow cubic CuSe@CdS composites with different sizes and strong localized surface plasmon resonance (LSPR) were prepared by selenizing size-tunable CuO templates and loading CdS nanoparticles. The size of hollow cubic CuSe can affect the surface area and the conduction band potential through the size effect, regulating the carrier behavior of the CuSe@CdS heterojunction.

Preoperative C-reactive Protein and Other Inflammatory Biomarkers as Predictors of Postoperative Complications in Colorectal Tumor Patients.

Objective: This study aims to explore the predictive value of preoperative C-reactive protein (CRP) and other inflammatory biomarkers: platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) for postoperative complications (infection, diarrhea, etc.) in colorectal tumor patients.

Methods: A cohort of 109 colorectal tumor patients who underwent surgical resection for colorectal cancer at the hospital from January 2021 to December 2022 were selected as the research subjects.

Peptostreptococcus anaerobius is a potential diagnostic biomarker of colorectal cancer.

Accumulating evidences have shown that Peptostreptococcus anaerobius (P.a) is abundantly enriched in the fetus of colorectal cancer (CRC) patients. P.

Identification of Biomarkers Associated with Heart Failure Caused by Idiopathic Dilated Cardiomyopathy Using WGCNA and Machine Learning Algorithms.

Background: The genetic factors and pathogenesis of idiopathic dilated cardiomyopathy-induced heart failure (IDCM-HF) have not been understood thoroughly; there is a lack of specific diagnostic markers and treatment methods for the disease. Hence, we aimed to identify the mechanisms of action at the molecular level and potential molecular markers for this disease.

Methods: Gene expression profiles of IDCM-HF and non-heart failure (NF) specimens were acquired from the database of Gene Expression Omnibus (GEO).

Bimetals Ni-Mo-S-Modified Hollow Cubic CuS for Visible-Light Photocatalytic H Evolution.

Photocatalysts with hollow structures have drawn great interest owing to their high specific surface area, which can enhance the photocatalytic performance. Herein, we designed the hollow cubic CuS@Ni-Mo-S nanocomposites by vulcanizing from the CuO template and loading the Ni-Mo-S lamellas. The CuS@Ni-Mo-S composites greatly improved the photocatalytic hydrogen performance.

Total Synthesis of the Alleged Structure of (+)-Fimbricalyxoid A.

An enantioselective total synthesis of the alleged structure of (+)-fimbricalyxoid A is reported. The synthetic strategy features a pyridine--oxidate-mediated S2' reaction to introduce an oxygen functionality at position C3 of the A-ring and a sequential three-step process via the cleavage of the C-O bonds and hemiketalization to form the 3,20-oxybridge. With this strategy, the target molecule was synthesized in 19% overall yield and 12 steps from our previously synthesized -fused octahydrophenanthrene (+)-.

A Three-Step Process to Facilitate the Enantioselective Assembly of -Fused Octahydrophenanthrenes with a Quaternary Stereocenter.

A three-step process for the enantioselective assembly of -fused octahydrophenanthrenes with a quaternary stereocenter is reported. This synthetic strategy relies on a regioselective γ-alkylation, a one-pot sequence of asymmetric hydrogenation and oxidation, and an intramolecular enolate arylation to facilitate the rapid and enantioselective construction of -fused octahydrophenanthrene scaffolds with an arylated all-carbon quaternary stereocenter concisely and efficiently.

Comparison of Clinical Outcomes Between Ticagrelor and Clopidogrel in Acute Coronary Syndrome: A Comprehensive Meta-Analysis.

Background: Ticagrelor is currently recommended for patients with the acute coronary syndrome (ACS). However, recent studies have yielded controversial results.

Objective: To compare the clinical outcomes between ticagrelor and clopidogrel in patients with ACS.

Evolution of Precipitated Phases during Creep of G115/Sanicro25 Dissimilar Steel Welded Joints.

This paper studies the evolution of the microstructure and microhardness in the G115 side of the G115/Sanicro25 dissimilar steel welded joint during the creep process. The joints were subjected to creep tests at 675 °C, 140 MPa, 120 MPa and 100 MPa. A scanning electron microscope equipped with an electron backscattering diffraction camera was used to observe the microstructure of the cross-section.

Copy number variation sequencing combined with quantitative fluorescence polymerase chain reaction in clinical application of pregnancy loss.

Purpose: In this study, we evaluated the feasibility of the combining CNV-seq and quantitative fluorescence polymerase chain reaction (QF-PCR) for miscarriage analysis in clinical practice.

Methods: Over a 35-month period, a total of 389 fetal specimens including 356 chorionic villi and 33 fetal muscle tissues were analyzed by CNV-seq and QF-PCR. Relationships between the risk factors (e.

Asymmetric Hydrogenation of β-Aryl Alkylidene Malonate Esters: Installing an Ester Group Significantly Increases the Efficiency.

Herein, we report a practical method for efficient asymmetric hydrogenation of β-aryl alkylidene malonates. With a site-specifically tailored chiral spiro iridium catalyst, a series of β-aryl alkylidene malonate esters were hydrogenated to afford chiral malonate esters with good to excellent enantioselectivities (up to 99% ee) and high turnover numbers (up to 19000). The results showed that installing an ester group in α,β-unsaturated carboxylic esters significantly increased the efficiency of their asymmetric hydrogenation reactions.

Outcomes in Participants with Renal Impairment from a Phase 3 Clinical Trial for Ceftolozane/Tazobactam Treatment of Nosocomial Pneumonia (ASPECT-NP).

In the phase 3 ASPECT-NP trial (NCT02070757), ceftolozane/tazobactam (C/T) was noninferior to meropenem for treatment of Gram-negative ventilated hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (vHABP/VABP). Here, we report outcomes in participants from ASPECT-NP with renal impairment (RI). Participants were categorized by their baseline renal function as follows: normal renal function (NRF; creatinine clearance [CL], ≥80 ml/min), mild RI (CL, >50 to <80 ml/min), moderate RI (CL, ≥30 to ≤50 ml/min), and severe RI (CL, ≥15 to <30 ml/min).

Kaempferol Regulates miR-15b/Bcl-2/TLR4 to Alleviate OGD-Induced Injury in H9c2 Cells.

Ischemic heart disease (IHD) is one of the world's leading causes of human death. Kaempferol (Kae) was proved to have anti-inflammatory, antioxidant, and anticancer effects. Such properties suggested that it might play protective roles in IHD.

Divergent Asymmetric Total Synthesis of Mulinane Diterpenoids.

A concise, divergent, asymmetric total syntheses of mulinane diterpenoids has been achieved. Specifically, a new strategy was developed featuring a key intramolecular Friedel-Crafts reaction to construct the chiral fused 5-6-6 tricyclic motif, followed by sequential Birch reduction, conjugate methylation, and homologation/ring-expansion reactions to furnish the desired 5-6-7 tricyclic skeleton bearing five contiguous stereocenters. With this efficient strategy, seven mulinane diterpenoids and two analogues were synthesized via late-stage functional modification or functionalization in 8.

Asymmetric Hydrogenation of Tetrasubstituted Cyclic Enones to Chiral Cycloalkanols with Three Contiguous Stereocenters.

A highly efficient iridium-catalyzed asymmetric hydrogenation of tetrasubstituted cyclic enones has been developed for the enantioselective synthesis of chiral cycloalkanols with three contiguous stereocenters. The C═O and C═C bonds of the enone substrates were hydrogenated sequentially in one pot with excellent enantioselectivity (92 to >99% ee) and diastereoselectivity (dr 95:5 to >99:1). The reaction provided a practical approach to all of the stereoisomers of the antiulcer drug rosaprostol.

PbBiGaBO, a new congruent-melting galloborate containing two types of asymmetric cations with a moderate birefringence.

PbBiGaBO, a new congruent-melting galloborate, which simultaneously contains two types of lone-pair cations and a π-conjugated system in one crystal structure, has been discovered through spontaneous crystallization. Single-crystal X-ray structural analysis shows that PbBiGaBO crystallizes in the monoclinic space group of C2/c. The parameters of the unit cell are a = 17.

Active performance of tetrahedral groups to SHG response: theoretical interpretations of Ge/Si-containing borate crystals.

As potential candidates for deep-UV nonlinear optical (NLO) crystals, borosilicates and borogermanates, which contain NLO-active groups such as B-O, Si-O and Ge-O, have fascinated many scientists. The crystal structures, electronic structures and optical properties of seven borates in different B/R (R = Si, Ge) ratios have been studied using DFT methods. Through the SHG-density, we find that besides the recognized contribution of the π-conjugation configuration of BO3 to second harmonic generation (SHG), the tetrahedra have a non-negligible influence.

[An analysis of articles published by academic groups in pediatrics in Chinese Journal of Pediatrics and their citations].

Objective: To explore academic significance and guiding function played by subspecialty groups of the Society of Pediatrics, Chinese Medical Association on Chinese pediatric clinical practice through a statistical analysis of the articles published by the subspecialty groups.

Method: Bibliometric methods were used to analyze the number of articles, article types, total citations, highly cited articles and the distribution of citing journals.

Result: Totally 7 156 articles were published in Chinese Journal of Pediatrics from 1993 (31) to 2012 (51), of which 187 by subspecialty groups of pediatrics (2.

[Association of hepatitis C virus genotype with glycolipid iron metabolism in Gansu Han population].

Objective: To investigate the association of hepatitis C virus (HCV) genotype with glycolipids iron metabolism in Gansu Han population.

Methods: The genotypes of HCV 1b type and 2a type were detected in Gansu Han HCV carriers. The Glu, Insulin, CHOL, TG, UIBC, TRF, TIBC, SF, Serum Iron, AST, ALT, TBil, IBil, DBil, ALP, GGT were measured and compared between patients with different HCV genotypes.

[Analysis of articles and citations of Chinese Journal of Pediatrics from 1950 to 2009].

Objective: To explore the articles, authors and citations of the articles published in Chinese Journal of Pediatrics, and have a clear view of the characteristics of this journal in its different development stages.

Method: Bibliometric methods were used to analyze the published articles, cooperation, regional distribution, core authors, corresponding authors and high-quantities of publication institutes, and also to calculate the number of citations per paper, types of citations, language-based citation number, Price index, self-cited rate and the distribution of journals based on citations.

Result: Totally 5534 academic articles were published during the 60 years, of which the number of articles written by more than one author was 4669 (80.

[An analysis of articles published in Chinese Journal of Pediatrics from 1996 to 2005].

Objective: To explore, on the basis of principles of bibliometrics, the distribution of the authors of the articles published in Chinese Journal of Pediatrics, and the types of the institutions and the different regions from where the manuscripts were submitted in order to make a clear view of the characteristics and the status of cooperations in pediatric research work; to ascertain, among them, the core authors, core institutes and core regions; and to analyze the significance of corresponding authors, a new regulation adopted by this Journal in recent years, and to explore, furthermore, the funding status of the studies.

Method: Based on the information drawn from Chinese Medical Current Content (CMCC), bibliometric method was used to analyze the publications in Chinese Journal of Pediatrics and their authorship during the period from 1996 to 2005.

Result: Totally 3337 academic articles were published during the ten years; of which the number of articles written by more than one authors was 2951, accounting for 88.