Publications by authors named "Linoel Curado Valsechi"

Article Synopsis
  • The study explores factors affecting prognosis in pediatric patients with different types of pineal region tumors over a 30-year period at a single institution.
  • It analyzes 151 patients and finds significant survival rate differences across tumor types, with germinoma having the best prognosis and atypical teratoid rhabdoid tumors leading to rapid mortality.
  • Key prognostic factors include gender, presence of metastasis, treatment approaches, and age, emphasizing the need for tailored, multidisciplinary treatment strategies for affected children.
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Objective: Pineal region tumors account for 2.7%-11% of all CNS tumors in children. In this series, the authors present their surgical results and long-term outcomes from a pediatric pineal region tumor cohort.

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The bobble-head doll syndrome (BHDS) is a rare acquired head movement disorder characterized by up and down or side-to-side movement, most commonly seen in the first decade of life. The syndrome occurs more often in lesions causing third ventricle dilatation such as suprasellar or third ventricle cyst, but it is also found in other pathologies associated with hydrocephalus like shunt dysfunctions, trapped fourth ventricle, congenital aqueductal stenosis, Dandy-Walker syndrome, and cerebellar malformations. The pathophysiology of this head movement has different origins theories; one states that this stereotyped movements empties the cyst and move the dome away from the foramina of Monro, which relieves the symptoms of hydrocephalus; the other suggests that the extrapyramidal tracts (rubrotegmentospinal and reticulospinal) are stimulated by the compression of dorsomedial nucleus of the thalamus by the cyst, whose tracts innervate the neck muscles resulting in the bobbling head movements.

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