Psychometric properties of AMAS and math anxiety prevalence among Chinese and Russian schoolchildren: a comparative study.

The purpose of this study was to compare the prevalence of math anxiety in Russian and Chinese schoolchildren across genders and ages. The Abbreviated Math Anxiety Scale (AMAS) was used as a measurement tool for assessing math anxiety. The factor structure of the AMAS and item invariance between Russian and Chinese schoolchildren were also examined.

A review of a colorimetric biosensor based on FeO nanozymes for food safety detection.

The issue of food safety poses a significant threat to human health. The colorimetric sensing method offers a highly sensitive response, visualization, and easy operation, making it highly promising for applications in the field of bioanalysis. FeO nanomaterials not only possess the advantages of a straightforward preparation method, customizable functionalities, and facile surface modification, but also exhibit excellent peroxidase activity.

The Carthamus tinctorius L. genome sequence provides insights into synthesis of unsaturated fatty acids.

Domesticated safflower (Carthamus tinctorius L.) is a widely cultivated edible oil crop. However, despite its economic importance, the genetic basis underlying key traits such as oil content, resistance to biotic and abiotic stresses, and flowering time remains poorly understood.

Enrichment and Evaluation of Antitumor Properties of Total Flavonoids from Maxim.

Flavonoids are important secondary metabolites found in Maxim., which is a precious reservoir of bioactive substances in China. To explore the antitumor actions of flavonoids (JMFs) from the waste branches of , the following optimized purification parameters of JMFs by macroporous resins were first obtained.

Design, synthesis and biological evaluation of structurally new 4-indolyl quinazoline derivatives as highly potent, selective and orally bioavailable EGFR inhibitors.

Targeting the epidermal growth factor receptor (EGFR) has been recognized as an effective strategy for treating non-small-cell lung cancer (NSCLC). Although several representative EGFR inhibitors have been approved for clinical use, it is highly desirable to develop highly potent and selective EGFR inhibitors with novel scaffolds because of the occurrence of acquired resistance after treatment. Here we first demonstrate that the 4-indolyl quinazoline derivatives could potently inhibit EGFR in vitro and in vivo, of which YS-67 effectively and selectively inhibits EGFR[WT] (IC50 = 5.

Synthesis and application of wetland plant-based functional materials for aqueous antibiotics removal.

Wetlands have been widely used in wastewater treatment and restoration of water bodies due to their ecological characteristics and functions. However, large amounts of plant residues are produced in wetlands every year and their treatment are facing large challenge. Synthesis of wetland plant-based functional materials (WPBFMs) has emerged as promising method for treating and recycling wetland plant residues.

Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC.

Lysine-specific demethylase 1 (LSD1) has been identified as an important epigenetic target, and recent advances in lung cancer therapy have highlighted the importance of targeting ferroptosis. However, the precise mechanisms by which LSD1 regulates ferroptosis remain elusive. In this study, we report that the inhibition of LSD1 induces ferroptosis by enhancing lipid peroxidation and reactive oxygen species (ROS) accumulation.

Discovery of YS-363 as a highly potent, selective, and orally efficacious EGFR inhibitor.

The Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the standard first-line therapy for EGFR-mutated NSCLC. However, long-term clinical treatment often leads to acquired drug resistance, making NSCLC refractory. Therefore, it is essential to design new EGFR inhibitors as potential drugs against NSCLC.

Multiple Metabolites Derived from Mushrooms and Their Beneficial Effect on Alzheimer's Diseases.

Mushrooms with edible and medicinal potential have received widespread attention because of their diverse biological functions, nutritional value, and delicious taste, which are closely related to their rich active components. To date, many bioactive substances have been identified and purified from mushrooms, including proteins, carbohydrates, phenols, and vitamins. More importantly, molecules derived from mushrooms show great potential to alleviate the pathological manifestations of Alzheimer's disease (AD), which seriously affects the health of elderly people.

Combined effects of microplastics and chlortetracycline on the intestinal barrier, gut microbiota, and antibiotic resistome of Muscovy ducks (Cairina moschata).

Antibiotics and microplastics (MPs) have become critical concerns worldwide because of their increasing amount and ecological risks to ecosystems. However, how MPs exposure affects the bioaccumulation and risks of antibiotics in waterfowls remains poorly understood. In this study, Muscovy ducks were exposed to single and combined contamination with polystyrene MPs and chlortetracycline (CTC) for 56 days, and the effects of MPs on CTC bioaccumulation and their risks in duck intestines were investigated.

Plastisphere microbiome: Methodology, diversity, and functionality.

Broad topics of the plastisphere in various environments are reviewed, including its methodologies, diversity, functionality, and outlook.

Transcriptomic responses of the fast-growing bacterium Vibrio natriegens during cold-induced loss of culturability.

Vibrio natriegens has massive biotechnological potential owing to its fast growth rate. However, this bacterium rapidly loses its culturability during low-temperature preservation (LTP), the reason for which is still unknown. To reveal the metabolic responses of V.

Quantification of the antagonistic and synergistic effects of Pb, Cu, and Zn bioaccumulation by living Bacillus subtilis biomass using XGBoost and SHAP.

Bioaccumulation and adsorption are efficient methods for removing heavy metal ions (HMIs) from aqueous environments. However, methods to quantifiably characterize the removal selectivity for co-existing HMIs are limited. In this study, we applied Shapley additive explanations (SHAP) following extreme gradient boosting (XGBoost) modeling, to generate SHAP values.

Beneficial Effects of Oleosomes Fused with Human Fibroblast Growth Factor 1 on Wound Healing via the Promotion of Angiogenesis.

In our previous study, human fibroblast growth factor 1 was successfully fused with oleosomes, energy-storing organelles of seeds, which are considered to be excellent "expression carriers" for substances with a convenient purification process. The present work aimed to explore the beneficial effects of oleosomes fused with human fibroblast growth factor 1 (OLAF) on wound healing. The data showed marked improvements in terms of the angiogenesis, vascular integrity, collagen and inflammation on the wound sites of rats with a full-thickness skin defect.

Genome-wide analysis of CtNF-YB and lipid synthesis regulation of CtNF-YB12 in Carthamus tinctorius L.

The nuclear Factor YB of Carthamus tinctorius L. increased the content of unsaturated fatty acids by regulating the expression of genes involved in fatty acid synthesis and oil accumulation. Safflower (Carthamus tinctorius L.

Xanthan gum/oil body-microgel emulsions with enhanced transdermal absorption for accelerating wound healing.

The oil body comprises lipid droplets surrounded by a surface embedded with oil body-related proteins. To form a drug delivery system, an oleosin can be fused with foreign proteins and bound to the oil body surface. Here, safflower oil bodies carrying oleosin-human epidermal growth factor (hEGF) were mixed with xanthan gum to form self-assembled polymers, referred as an oil body microgel emulsion (OBEME) without any chemical crosslinking agent.

Ultrasonic-Assisted Extraction of Flavonoids from Maxim.: Artificial Intelligence-Based Optimization, Kinetics Estimation, and Antioxidant Potential.

Ultrasonic-assisted extraction (UAE) of flavonoids (JMBF) from Maxim., an important industrial crop in China, was investigated in the present study. To improve the extraction efficiency of JMBF, suitable UAE was proposed after optimization using a hybrid response surface methodology-artificial neural network-genetic algorithm approach (RSM-ANN-GA).

Exploration of Strategies for Organic Integration of Labor Education and Occupational Therapy for College Students.

This paper analyzes the actual functions of the labor education and occupational therapy phase through an in-depth study of labor education and occupational therapy for college students and explores the strategies of organic integration of labor education and occupational therapy for college students. This paper carries out a holistic theoretical construction of labor education in schools and systematically analyzes the components of labor education objectives in colleges and universities, labor education contents in schools, labor education implementation in schools, and labor education evaluation in schools. The main goal of labor education in colleges and universities is to guide students in establishing a scientific concept of labor and constructing a labor education resource system.

Toxicity alleviation and metabolism enhancement of nonylphenol in green algae Dictyosphaerium sp. by NaHCO.

Nonylphenol (NP) toxicity limits the improvements in its algal remediation efficiency. This study comprehensively investigated the performance and mechanism of NaHCO-driving effects on NP-exposed algae. The results showed that NaHCO enhanced algal resistance to NP and the corresponding EC values increased 1.

Effects of organic fertilization on functional microbial communities associated with greenhouse gas emissions in paddy soils.

Soil microbial communities play a key role in the biochemical processes and nutrient cycles of the soil ecosystem and their byproducts, including greenhouse gases (GHGs). Organic fertilization influences bacterial soil biodiversity and is an essential emission source of GHGs in paddy soil ecosystems. However, the impact of organic fertilization on the functional microorganisms associated with the GHGs methane and nitrous oxide remains unknown.

Transformation of sulfidized nanoscale zero-valent iron particles and its effects on microbial communities in soil ecosystems.

Sulfidized nanoscale zero-valent iron (S-nZVI) is a promising material for in situ soil remediation. However, its transformation (i.e.