Machine learning-based identification of a novel prognosis-related long noncoding RNA signature for gastric cancer.

Gastric cancer (GC) is one of the most common malignancies with a poor prognosis. Immunotherapy has attracted much attention as a treatment for a wide range of cancers, including GC. However, not all patients respond to immunotherapy.

Effects of influent salinity on water purification and greenhouse gas emissions in lab-scale constructed wetlands.

Salinity has a significant impact on the sewage treatment efficiency of constructed wetlands (CWs), as well as affecting the greenhouse gas emissions of CWs. A lab-scale CW simulation system was constructed to observe the treatment efficiency and greenhouse gas flux occurring in CWs at different influent salinities (0%, 0.5%, 1.

Comparative proteomic and genomic analyses of Brucella abortus biofilm and planktonic cells.

The present study aimed to explore the differences in protein and gene expression of Brucella abortus cultured under biofilm and planktonic conditions. The proteins unique to biofilms and planktonic B. abortus were separated by two‑dimensional (2‑D) electrophoresis and then identified by matrix‑assisted laser desorption/ionization‑tandem time of flight‑mass spectrometry (MALDI‑TOF/TOF‑MS).

Association between hypokalemia and small bowel capsule endoscopy completion rates in patients in South China: A prospective single-center study.

Background/aims: Approximately 20-30% of small bowel capsule endoscopies (SBCEs) do not reach the cecum at the completion of the examination. We aimed to determine whether hypokalemia influences the completion rate and small bowel transit time (SBTT) of SBCE.

Patients And Methods: From January to December 2017, 112 patients (18-75 years old) who underwent SBCE were assessed consecutively for enrolment in our study.

[Effects of Different Substrates and Particle Sizes on Wastewater Purification].

Choosing suitable substrate is key to improving the efficiency of wetland decontamination. However, little is known about the effect of particle size. In order to study the effect of substrate type and size on COD, TN, and TP removal from sewage, 1-2, 2-4, and 4-8 mm zeolite, 2-4, 4-8, and 8-16 mm gravel, and 2-4, 3-5, and 6-8 mm anthracite were selected for establishment of the constructed system of experimental media with three replications.

Efficacy of two different dosages of levofloxacin in curing Helicobacter pylori infection: A Prospective, Single-Center, randomized clinical trial.

Bismuth + proton pump inhibitor (PPI) + amoxicillin + levofloxacin is one of the bismuth quadruple therapy regimens widely used for the eradication of H. pylori infection. The recommended dosage of levofloxacin is 500 mg once daily or 200 mg twice daily to eradicate H.

The effects of air pollution on mortality and clinicopathological features of esophageal cancer.

This study aimed to estimate the associations between air pollution and esophageal cancer. In the ecologic cross-sectional study, correlation analyses were made between city-level mean concentrations of particulate matter less than 10μm in aerodynamic diameter (PM), SO, NO and city-level age-standardized mortality rates of esophageal cancer in Shandong Province, China. PM (=0.

Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma.

We aimed to investigate the pattern of expression and clinical significance of isocitrate dehydrogenase 1(IDH1) in esophageal squamous cell carcinoma (ESCC). The IDH1 expression was determined by quantitative real-time polymerase chain reaction, immunohistochemistry, and Western blot analysis using 38 pairs of frozen tissues. Enzyme-linked immunosorbent assay was employed to measure 67 pairs of serum samples from patients and their controls to evaluate its diagnostic value.

Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients.

Germline mutations in BRCA1 and BRCA2 are the most penetrating genetic predispositions for breast and ovarian cancer, and their presence is largely ethnic-specific. Comprehensive information about the prevalence and spectrum of BRCA mutations has been collected in European and North American populations. However, similar information is lacking in other populations, including the mainland Chinese population despite its large size of 1.