Publications by authors named "Lining Rui"

Article Synopsis
  • Intervertebral disc degeneration (IVDD) leads to lower back pain and involves loss of specific cells and degradation of the supporting structure, influenced by factors like inflammation and oxidative stress.
  • The glutathione (GSH) redox system serves as a crucial antioxidant in cells, combating oxidative stress by converting harmful substances into less dangerous forms.
  • Research highlights GSH's role in various types of cell death linked to IVDD, and exploring small molecule compounds that influence GSH levels could offer new strategies for preventing or slowing IVDD progression.
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Osteoporosis development is linked to abnormal bone marrow mesenchymal stem cells (BMSCs) differentiation. N6-methyladenosine (mA), a prevalent mRNA modification, is known to influence BMSCs' osteogenic capacity. Qianggu decoction (QGD), a traditional Chinese medicine for osteoporosis, has unknown effects on BMSCs differentiation.

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Objective: The aim of this study was to compare the efficacy and safety of a novel percutaneous pedicle screw fixation and vertebral reconstruction (PPSR) vs. that of open pedicle screw fixation (OPSF) in the treatment of thoracolumbar fractures.

Methods: This retrospective study enrolled 153 patients who underwent PPSR and 176 patients who received OPSF.

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