Publications by authors named "Linhuizi Lu"
Article Synopsis
- Mitochondria are critical for heart energy metabolism, and targeting this metabolism could help treat ischemic heart disease (IHD) using astragaloside IV (AST).
- Researchers used various methods, including data collection on genes, network analysis, and molecular docking, to identify potential targets of AST related to mitochondrial energy metabolism in IHD.
- The study found 1713 IHD-related genes, 528 related to energy metabolism, and identified key targets of AST, showing promising binding affinities and potential pathways involved in regulating these targets in the context of IHD.
Protection of the structural and functional integrity of the blood-brain barrier (BBB) is crucial for treating ischemic stroke (IS). Hydroxysafflor yellow A (HSYA) and quercetin (Quer), two main active components in the edible and medicinal plant L., have been reported to exhibit neuroprotective effects.
View Article and Find Full Text PDFCircular RNAs (circRNAs) play a role in sepsis-related autophagy. However, the role of circRNAs in autophagy after sepsis-induced cardiomyopathy (SICM) is unknown, so we explored the circRNA expression profiles associated with autophagy in an acute sepsis mouse model. At a dose of 10 mg/kg, mice were intraperitoneally administered with lipopolysaccharides.
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