MicroRNA-1205 promotes breast cancer cell metastasis by regulating epithelial-to-mesenchymal transition via targeting of CDK3.

Metastasis poses a huge obstacle to the survival of breast cancer patients. The microRNA miR-1205 acts as a tumor suppressor in various cancers, but its roles in breast cancer and metastasis remain unclear. To elucidate its function in breast cancer progression, we analyzed miR-1205 expression in human tumor samples and carried out a series of functional studies in in vitro and in vivo.

Intervertebral disk regeneration in a rat model by allopurinol-loaded chitosan/alginate hydrogel.

Intervertebral disk degeneration remains one of the most challenging health problems. In the current study, allopurinol was loaded into the chitosan nanoparticles and then incorporated into chitosan/alginate hydrogels and then further studied for its disk regeneration potential in a rat model. In vitro studies were performed to characterize the hydrogel system, including scanning electron microscopy, cell viability assay, cytoprotection assay, cell migration assay, swelling assay, and drug release assay.

Effect of Nanoparticle Addition on Evaporation of Jet Fuel Liquid Films and Nanoparticle Deposition Patterns during Evaporation.

Jet fuel-based nanofluid fuel has been proposed for improving the energy density and utilization efficiency of jet fuel that is widely applied in aircraft powered by aviation turbine engines. To recognize the evaporation behavior of the formed liquid film as a jet fuel-based nanofluid sprayed onto the engine wall or blades, this paper presents the evaporation and deposition characteristics of the jet fuel-based nanofluid liquid film adhering on the hydrophilic substrate. The changes in contact line, contact angle, volume, and deposition pattern during liquid film evaporation under different substrate temperatures, different nanoparticle concentrations, and different kinds of nanoparticle additions were investigated.

Understanding of Contradiction on Concentration Effect on Stability, Physical Properties, Evaporation and Microexplosion Characteristics of Al/JP-10/Oleic Acid Nanofluid Fuel.

An Al/JP-10/oleic acid nanofluid fuel system has demonstrated potential in advanced combustion for aviation turbine engines. To improve the energy density of nanofluid fuel, a higher Al concentration requirement needs to be met. Correspondingly, a higher surfactant oleic acid concentration is required to maintain better dispersion stability.

Effect of Nanoparticle Concentration on Physical and Heat-Transfer Properties and Evaporation Characteristics of Graphite/-Decane Nanofluid Fuels.

-Decane-based nanofluid fuels could be one of the most promising alternative fuels as aviation kerosene for aerospace application. However, the physical and heat-transfer properties of -decane-based nanofuels have been rarely studied, and the influence of the concentration of nanoparticles on the evaporation characteristics of -decane-based fuels has been sparsely investigated. This paper investigated physical and heat-transfer properties and evaporation characteristics of graphite/-decane nanofluid fuels and emphasized the concentration effect of adding graphite nanoplatelets (GNPs) on these characteristics.

Thickness-dependent band gap of α-InSe: from electron energy loss spectroscopy to density functional theory calculations.

α-InSe has attracted increasing attention in recent years due to its excellent electrical and optical properties. Especially, attention has been paid to its peculiar ferroelectric and piezoelectric properties which most other two-dimensional (2D) materials do not possess. This paper presents the first measurement of the thickness-dependent band gaps of few-layer α-InSe by electron energy loss spectroscopy (EELS).

Sinomenine ameliorates intervertebral disc degeneration via inhibition of apoptosis and autophagy and .

Background: Aberrant apoptosis in nucleus pulposus (NP) cells is the primary cause of intervertebral disc degeneration (IDD). In contrast, a large number of studies have confirmed that autophagy may protect NP cells from apoptosis. Sinomenine is an alkaloid monomer, which has been reported to stimulate cell autophagy.

Band-inverted gaps in InAs/GaSb and GaSb/InAs core-shell nanowires.

The [111]-oriented InAs/GaSb and GaSb/InAs core-shell nanowires have been studied by the 8 × 8 Luttinger-Kohn Hamiltonian to search for non-vanishing fundamental gaps between inverted electron and hole bands. We focus on the variations of the band-inverted fundamental gap, the hybridization gap, and the effective gap with the core radius and shell thickness of the nanowires. The evolutions of all the energy gaps with the structural parameters are shown to be dominantly governed by the effect of quantum confinement.

Directly correlating the strain-induced electronic property change to the chirality of individual single-walled and few-walled carbon nanotubes.

We fabricate carbon nanotube (CNT)-field effect transistors (FETs) with a changeable channel length and investigate the electron transport properties of single-walled, double-walled and triple-walled CNTs under uniaxial strain. In particular, we characterize the atomic structure of the same CNTs in the devices by transmission electron microscopy and correlate the strain-induced electronic property change to the chirality of the CNTs. Both the off-state resistance and on-state resistance are observed to change with the axial strain following an exponential function.

Electroluminescence from serpentine carbon nanotube based light-emitting diodes on quartz.

A light-emitting diode is fabricated and characterized on a semiconducting serpentine CNT which has many parallel segments with identical chirality. Compared with the individual CNT and CNT-film devices, the device with parallel segments shows improvement of an order of magnitude in current, significantly larger electroluminescent intensity, and narrower emission bands. Serpentine nanotubes are an ideal choice for practical applications of CNT-based light sources.

Model GW study of the late transition metal monoxides.

The model GW method [F. Gygi and A. Baldereschi, Phys.

Synthesis, structure and charge transport properties of Yb(5)Al(2)Sb(6): a zintl phase with incomplete electron transfer.

We report the synthesis, structure, spectroscopic properties, charge and thermal transport, and electronic structure of a new member of the Zintl family, Yb(5)Al(2)Sb(6). The compound crystallizes in the Ba(5)Al(2)Bi(6) structure type and requires the addition of Ge or Si in the synthesis, which appears to act as a catalyst. Yb(5)Al(2)Sb(6) has an anisotropic structure with infinite anionic double chains cross-linked by Yb(2+) ions.