Publications by authors named "Linhao Zhu"

Due to the good balance of efficiency and stability, CsPbIBr perovskite solar cells (PSCs) recently have attracted widespread attention. However, the improvement in photovoltaic performance for CsPbIBr PSCs was mainly limited by massive defects and unmatched energy levels. Surface modification is the most convenient and effective strategy to decrease defect densities of perovskite films.

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Black phase CsPbI perovskites have emerged as one of the most promising materials for use in optoelectronic devices due to their remarkable properties. However, black phase CsPbI usually possesses poor stability and involves a phase change process, resulting in an undesired orthorhombic (δ) yellow phase. Here, the enhanced stability of CsPbI nanocrystals is achieved by incorporating the Cu ion into the CsPbI lattice under mild conditions.

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Article Synopsis
  • The study investigated the link between genetic variants in ZC3HC1 and SMARCA4 and the risk of hypertension among the Chinese Han population.
  • The team analyzed genetic data from 350 hypertensive patients and 483 healthy controls using the Agena MassArray platform and calculated risk associations through statistical models.
  • Findings indicated that specific SNPs in ZC3HC1 and SMARCA4 were associated with a lower risk of hypertension, suggesting these genetic variants could offer protective benefits against the condition.
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Background: Tuberculosis (TB) is a significant worldwide health problem, and is caused by Mycobacteria tuberculosis. Recent studies have suggested that FOXO3 plays vital roles in the risk of immune-related infectious diseases such as TB.

Methods And Results: The present study aimed to evaluate FOXO3 genetic variants and TB risk.

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Background: Genetic polymorphisms in numerous pharmacogenetics studies were regarded as the essential factors involved in the response to or metabolism of drugs. These genetic variants called very important pharmacogenetic (VIP) variants played a role in drugs metabolism, which have been summarized in the PharmGKB database. In this study, we genotyped 80 VIP variants from the PharmGKB in 100 members of Blang volunteers from Yunnan province.

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Aim: High-altitude pulmonary edema (HAPE), as a multifactorial disease, is caused by stress failure and involves both environmental and genetic factors. Study shows that IL-1 receptors can selectively decrease the oxygen arterial hypertension and influence the blood coagulation. So we evaluated whether genetic polymorphisms in IL1R1 and 1L1R2 genes are associated with the risk of HAPE in Chinese Han population.

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Ischemic stroke (IS) is a complex disease caused by an obstruction within a brain-supplying blood vessel that involves both genetic and environmental factors. In this study, we evaluated the association of genetic polymorphisms in the AHSG gene with ischemic stroke risk in the Chinese population. A case-control study was conducted that included 477 nephropathy patients and 490 healthy controls.

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Aims: The role of inflammatory cytokines in High-altitude pulmonary edema (HAPE) remains unclear. The purpose of this study was to evaluate the role of IL4 and IL6 gene polymorphism in the development of HAPE in Chinese people.

Methods: In the present study, we screened ten polymorphisms of IL4 and IL6 gene in 265 HAPE and 303 healthy volunteers.

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Schizophrenia (SCZ) is a highly heritable, chronic, severe psychiatric disorder associated with significant financial costs to families and societies. In this case-control study, we investigated the associations between seven SNPs in CHRNA3 gene and the risk of SCZ.A total of 1071 (384 cases and 687 controls) unrelated subjects were recruited for our association study.

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Fat mass (FM) and fat-free mass (FFM) are important elements to evaluate nutritional status. The aims of this study were to establish reference values for FM and FFM of limbs, develop percentile distributions and assess age-related regional differences in body composition by multifrequency bioelectrical impedance analyzer (BIA) in healthy adults. A cross-sectional study was conducted on 3419 healthy subjects, 1595 men and 1824 women.

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Pharmacogenetics is the genetic basis of pharmacokinetics, genetic testing, and clinical management in diseases. Evaluation about genetic alterations of drug metabolizing enzymes in human genome contributes toward understanding the interindividual and interethnic variability for clinical response to potential toxicants. CYP2E1 gene encodes a drug-metabolizing enzyme that metabolizes mostly small, polar molecules, including toxic laboratory chemicals.

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Cytochrome P4502E1 (CYP2E1) gene genetic polymorphisms vary markedly in frequency among different ethnic and racial groups.We studied the genotype distributions and allele frequencies of 3 CYP2E1 polymorphisms: CYP2E11A, CYP2E17A, and CYP2E17C by polymerase chain reaction technique in a sample of 100 healthy subjects representing Tibetan population.The frequencies of CYP2E11A, 7A, and 7C alleles were 0.

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High altitude pulmonary edema (HAPE) is a paradigm of pulmonary edema. Mutations in regulator of telomere elongation helicase1 (RTEL1) represent an important contributor to risk for pulmonary fibrosis. However, little information is found about the association between RTEL1 and HAPE risk.

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High-altitude pulmonary edema (HAPE) is a hypoxia-induced, life-threatening, pulmonary edema, which is characterized by exaggerated pulmonary hypertension caused by stress failure. ACYP2 was found to associated with telomere length, the aim of this study was to identify whether ACYP2 polymorphisms increase or decrease HAPE risk in the Chinese Han individuals.In present study, we have genotyped 7 single-nucleotide polymorphisms (SNPs) in ACYP2 to determine the haplotypes in a case-control study with 265 HAPE patients and 303 healthy individuals.

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