Publications by authors named "Linh Thuy Le"
Background/objectives: Gastric cancer is one of the leading malignancies worldwide. B vitamins play important roles in DNA synthesis and methylation because they are considered co-enzymes in one-carbon metabolism. There is inconclusive evidence regarding the associations between dietary vitamins B, B, and B with the risk of gastric cancer in different epidemiologic studies.
View Article and Find Full Text PDFPolyunsaturated fatty acids (PUFAs) are fatty acids, containing more than one double bond and have both anti-inflammatory properties and inhibit tumor progression effects as well as carcinogenic properties. There is inconclusive evidence regarding the effect of PUFA intake on gastric cancer in diverse populations. We, therefore, aimed to determine the association between PUFA intake and risk of gastric cancer in a hospital-based case-control study comprising 1182 incident cases of gastric cancer and 2965 controls in Vietnam.
View Article and Find Full Text PDFThere is inconclusive evidence on the role of dietary intake of vitamin B in cancer. We evaluated the association between vitamin B intake and cancer risk in a hospital-based case-control study, comprising 3,758 cancer cases and 2,995 controls in Vietnam. Vitamin B intake was derived from the validated food frequency questionnaire.
View Article and Find Full Text PDFWhile selenium is a cofactor of several antioxidant enzymes against cancer and is essential for human health, its excess intake may also be harmful. Though a safe intake of selenium has recently been recommended, it is not well understood in the Asian population. We aimed to determine the association between dietary intake of selenium and cancer risk in a case-control study of 3758 incident cancer cases (i.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore the differences between male and female rats during sepsis, specifically looking at how the beta1-adrenergic blocker landiolol affects septic cardiomyopathy in both sexes.
- It was found that male rats experienced significant changes in biological processes during sepsis, including decreased cell organization and contractile function, while these changes were less pronounced in female rats.
- Landiolol effectively reversed several gene expression issues caused by sepsis in males, but had limited impact on females, underscoring notable sex differences in response to treatment.
Objectives: To investigate any gender effect of the beta-1 adrenergic blocker, landiolol, on cardiac performance and energy metabolism in septic rats, and to explore the expression of genes and proteins involved in this process.
Design: Randomized animal study.
Setting: University research laboratory.