Inhibition of pro-inflammatory cytokines by homalolide A and homalomenol A isolated from rhizomes of .

Inflammation, a natural process of the innate immune system, involves elevated levels of various proinflammatory mediators, such as, nitric oxide (NO) and prostaglandin (PGE), cytokines such as interleukin 6 (IL-6), interleukin 10 (IL-10) and tumor necrosis factor alpha (TNF-α), and enzymes including inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). This study investigated the anti-inflammatory effects of homalolide A () and homalomenol A (), two sesquiterpenoids isolated from the rhizome of , on lipopolysaccharide (LPS)- stimulated macrophage cells. The results demonstrated that both and dose-dependently inhibited the production of PGE, TNF-α and IL-6 in RAW 264.

Live birth after in vitro maturation in women with gonadotropin resistance ovary syndrome: report of two cases.

Purpose: Gonadotropin-resistant ovary syndrome (GROS) is a rare endocrine disorder that causes hypergonadotropic hypogonadism, amenorrhea, and infertility. This study reports live birth in two women with GROS who underwent fertility treatment with in vitro maturation (IVM).

Methods: Both patients had primary infertility, amenorrhea (primary and secondary), typical secondary sexual characters, elevated gonadotropin levels, normal ovarian reserve, normal chromosomal characteristics, and previous nonresponsiveness gonadotropin stimulations.

Indigenous knowledge in relation to climate change: adaptation practices used by the Xo Dang people of central Vietnam.

Even though indigenous knowledge (IK) is considered as one of the most effective strategies in response to climate change issues, this form is not being sufficiently integrated into the climate change planning and policy at both local and national levels in Vietnam. This study investigates the role of the traditional agricultural practices of the Xo Dang ethnic minority groups in Central Vietnam and provides insights into the factors that influence farmers to adopt these practices in response to climate change. Primary data was obtained through three focus group discussions and 87 household surveys involving the Xo Dang people through face-to-face semi-structured interviews in the Tra Doc commune, Bac Tra My district, Quang Nam province, Central Vietnam.

Factors associated with nicotine dependence during methadone maintenance treatment: findings from a multisite survey in Vietnam.

Objectives: Smoking is associated with adverse health outcomes among drug users, including those in treatment. To date, however, there has been little evidence about smoking patterns among people receiving opioid-dependence treatment in developing countries. We examined self-reported nicotine dependence and associated factors in a large sample of opioid-dependent patients receiving methadone maintenance treatment (MMT) in northern Vietnam.

Preference of methadone maintenance patients for the integrative and decentralized service delivery models in Vietnam.

Background: Integrating and decentralizing services are essential to increase the accessibility and provide comprehensive care for methadone patients. Moreover, they assure the sustainability of a HIV/AIDS prevention program by reducing the implementation cost. This study aimed to measure the preference of patients enrolling in a MMT program for integrated and decentralized MMT clinics and then further examine related factors.