Dominant spoilage bacteria in crayfish alleviate ultrasonic stress through mechanosensitive channels but could not prevent the process of membrane destruction.

Although there have been many studies on the efficacy of ultrasonic inactivation, the stress resistance mechanism of bacteria is still a challenge for complete ultrasonic inactivation. In this study, the dominant spoilage bacteria in crayfish, Shewanella baltica (S. baltica) and Aeromonas veronii (A.

Biological Sex Disparities in the Economic Burden of Tobacco Use: A Comparative Analysis between Men and Women in China.

To examine the impact of tobacco use on the economic costs between biological sex differences, we utilized propensity score matching and human capital methods to analyze the economic costs associated with smoking. Our findings reveal a nuanced pattern in the economic burden: although men who smoke bear a higher overall economic cost, the individual impact on women who smoke is significantly more profound. As a result, there exists a distinct disparity in the distribution of economic consequences stemming from tobacco use between men and women.

Influence of the examination position and distension medium on the rectal sensory test in patients with functional constipation.

Purpose: To evaluate the impact of two different parameters (body position and distension medium) on the rectal sensory test in patients with functional constipation and provide data support for the development of standardized operating procedures in clinical practice.

Methods: Based on a single-center process of the rectal sensory test, 39 patients with functional constipation were recruited for rectal sensory test under different body positions and distension mediums.

Results: Among the items of the Constipation Scoring System, the score of frequency of bowel movements showed a negative correlation with the first constant sensation volume (r = -0.

How does the e-cigarette industry respond to tax adjustments? Evidence from China.

Introduction: China enacted an excise tax on e-cigarettes in November 2022, which offers a distinctive opportunity to examine the industry's reactions to this fiscal adjustment. This study delves into the industry's pricing strategies following the introduction of the excise tax, facilitating a thorough assessment of the subsequent impact on market dynamics and the government's revenue streams.

Methods: We developed a TaXSiM model specifically tailored for e-cigarettes in China by integrating the country's e-cigarette tax framework.

Yiqi Kaimi prescription regulates protein phosphorylation to promote intestinal motility in slow transit constipation.

Ethnopharmacological Relevance: The clinical efficacy of the Yiqi Kaimi prescription has been confirmed in slow transit constipation. However, the effects and biological mechanism of Yiqi Kaimi prescription are still unclear.

Aims Of The Study: To identify the effects of Yiqi Kaimi prescription on intestinal motility; To reveal the potential key targets and pathways of Yiqi Kaimi prescription for the treatment of slow transit constipation.

Differential expression of zinc finger CCHC-type superfamily proteins in thyroid carcinoma and their associations with tumor immunity.

Background: The zinc-finger CCHC-type (ZCCHC) superfamily proteins are characterized by the shared sequence CX2-CX4-HX4-C and thought to own high affinity to single-stranded nucleic acids, particularly RNAs. In humans, a total of 24 ZCCHC proteins have been annotated in the HUGO Gene Nomenclature Committee (HGNC, https://www.genenames.

Inactivation of Vibrio parahaemolyticus and retardation of quality loss in oyster (Crassostrea gigas) by ultrasound processing during storage.

The health problems caused by foodborne pathogens of raw oysters have been widely concerned. Traditional heating methods tend to lead the loss of the original nutrients and flavors, in this study, the nonthermal ultrasound technology was applied to inactivate Vibrio parahaemolyticus on raw oysters, and the retardation effects on microbial growth and quality loss of oysters stored at 4 ℃ after ultrasonic treatment were also investigated. After treated by 7.

Stresses make microbe undergo programmed cell death: Mechanisms and opportunities.

In recent years, programmed cell death (PCD) has attracted the attention of many scholars as an active death process. PCD refers to an active extinction process that occurs after cells receive a certain signal or are stimulated by certain factors in order to maintain the stability of the internal environment. It is orchestrated by precise molecular circuitry.

The microbial stress responses of Escherichia coli and Staphylococcus aureus induced by chitooligosaccharide.

Intermediate-state bacteria produced in the process of bacteriostasis have always been a potential threat to public health, but they are very easy to be overlooked. As a natural and non-toxic biological antibacterial agent, chitooligosaccharide (COS) has attracted the public's attention. However, little is known about the microbial stress response during the antibacterial process of COS.

Continuous rise of the tropopause in the Northern Hemisphere over 1980-2020.

Tropopause height () is a sensitive diagnostic for anthropogenic climate change. Previous studies showed increases in over 1980–2000 but were inconsistent in projecting trends after 2000. While generally responds to temperature changes in the troposphere and stratosphere, the relative importance of these two contributions is uncertain.

Deeper insight into hydrolysis mechanisms of polyester/cotton blended fabrics for separation by explicit solvent models.

Aiming to get a deeper and accurate understanding on separation of polyester/cotton blended fabrics in subcritical water, the hydrolysis mechanisms of cellulose and polyester were studied using dispersion-corrected density functional theory (DFT-D) method with and without explicit HO under the conductor-like screening model (COSMO) set. The number and locations of explicit HO were determined by their likely functions including being dissociation and solvent and catalyst. The calculations disclosed that explicit HO provide inductive activation on glycosidic bond of cellulose and ester groups at the center of polyester and the assistance on the transfer of proton as proton-carrier and as catalyst of proton shuttle, affecting the reaction and activation energies in a realistic manner.

Quercetin-loaded mixed micelles exhibit enhanced cytotoxic efficacy in non-small cell lung cancer .

In the present study, quercetin (QUR)-loaded mixed micelles (QUR-M) were prepared with the aim of improving the physicochemical and anticancer efficacy of QUR in lung cancer cells. The mixed micelles comprised tocopheryl polyethylene glycol 1000 succinate (TPGS) and a 1,2-distearoyl--glycero-3-phosphatidylethanolamine derivative of polyethylene glycol. The nanosized QUR-M exhibited a pH-responsive and controlled release of QUR that is likely to be beneficial in cancer treatment.

Optimizing a desirable fare structure for a bus-subway corridor.

This paper aims to optimize a desirable fare structure for the public transit service along a bus-subway corridor with the consideration of those factors related to equity in trip, including travel distance and comfort level. The travel distance factor is represented by the distance-based fare strategy, which is an existing differential strategy. The comfort level one is considered in the area-based fare strategy which is a new differential strategy defined in this paper.