Publications by authors named "Lingyu Lin"

Article Synopsis
  • Postoperative cognitive dysfunction (POCD) is a complication linked to negative outcomes after cardiac surgery, and this study examines preoperative hypersensitive C-reactive protein (Hs-CRP) as a potential predictor of POCD in patients with valvular heart disease (VHD).
  • Analyzing data from 372 VHD patients, the study found a 27.6% incidence of POCD one month post-surgery, with significant differences in age, education level, Hs-CRP levels, and duration of mechanical ventilation between patients who developed POCD and those who did not.
  • The findings suggest that elevated preoperative Hs-CRP levels are an independent risk factor for POCD,
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Background: Prolonged mechanical ventilation (PMV) is a common complication after cardiac surgery and is considered a risk factor for poor outcomes. However, the incidence and in-hospital mortality of PMV among cardiac surgery patients reported in studies vary widely, and risk factors are controversial.

Methods: We searched four databases (Web of Science, Cochrane Library, PubMed, and EMBASE) for English-language articles from inception to October 2023.

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Background: Enhanced respiratory muscle management is imperative in cardiac surgery patients due to their universal risk of decreased perioperative respiratory muscle strength.

Objectives: Most existing articles primarily examine respiratory muscle exercise during either the preoperative, postoperative, or at-home phases. Consequently, there is a crucial need to consolidate the evidence for respiratory muscle exercise throughout the perioperative period of cardiac surgery.

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Article Synopsis
  • Poor sleep quality is linked to worse clinical outcomes in patients with acute aortic dissection, increasing risks like postoperative delirium, in-hospital death, and prolonged mechanical ventilation.
  • Patients with poor sleep quality had significantly higher rates of complications compared to those with good sleep quality, indicating that sleep quality can affect recovery.
  • The study suggests that quickly assessing sleep quality preoperatively could help identify patients at greater risk for adverse outcomes, allowing for better management and care strategies.
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Purpose: Many shift nurses experience poor sleep quality, and the effect on nurses' cognitive function remains unclear. The study aims to investigate sleep status and explore its association with cognitive function.

Methods: This descriptive cross-sectional study was conducted in a tertiary care hospital in Fujian, China between March and September 2022.

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Article Synopsis
  • The study aimed to explore differences in clinical characteristics and hospital outcomes between male and female patients undergoing surgery for acute type A aortic dissection (AAAD).
  • It included 1137 patients from a cardiac surgery department, analyzing data for outcomes like in-hospital mortality and postoperative complications, with findings showing some differences in symptom presentation and complication rates.
  • Ultimately, the in-hospital mortality rates were similar for both sexes, but females had higher rates of postoperative arrhythmia, while males faced more acute kidney injury and gastrointestinal hemorrhage, highlighting the need for sex-specific considerations in treatment approaches.
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Malnutrition is linked to adverse outcomes in post-cardiac surgery patients. This study investigates the correlation between the Geriatric Nutritional Risk Index (GNRI) and adverse hospital outcomes in patients following cardiac surgery. This retrospective study included elderly patients with heart disease who were admitted to the Department of Cardiology, Fujian Medical University Union Hospital from January 2020 to December 2022.

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Background: Numerous recent studies have found a strong correlation between intestinal flora and the occurrence of hypertension. However, it remains unclear whether fecal microbiota transfer might affect the blood pressure of the host. This study aimed to quantify both associations.

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Background: The blood-urea-nitrogen (BUN)-to-serum-albumin (ALB) ratio (BAR) has been identified as a novel indicator of both inflammatory and nutritional status, exhibiting a correlation with adverse cardiovascular outcomes. This study aims to investigate the potential predictive value of BAR levels at admission for the development of CIN in patients undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI).

Methods: Retrospective data were collected from patients who were admitted and underwent CAG or PCI between January 2018 and December 2022 at the Cardiac Medical Center of Union Hospital of Fujian Medical University, and the patients were divided into CIN and non-CIN groups.

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Hypertension is a major public health issue worldwide. The imbalance of gut microbiota is thought to play an important role in the pathogenesis of hypertension. The authors conducted the systematic review and meta-analysis to clarify the relationship between gut microbiota and hypertension through conducting an electronic search in six databases.

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Background: Multiple guidelines recommend that families be involved in the care of ICU patients, which has been widely used in ICU delirium management in recent years. Postoperative delirium (POD) occurs frequently after cardiac surgery and is associated with poor outcomes; however, the effects of family intervention on this group are rarely studied.

Objectives: This study aimed to investigate the effects of family intervention on the incidence of POD and the ICU prognoses of patients undergoing cardiac valve surgery.

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Background: Although the research on gender in acute type A aortic dissection (AAAD) patients has increased in recent years, the results are still controversial. The effect of time of onset on in-hospital mortality in patients with AAAD of different gender is unclear. The purpose of this study was to investigate the effect of onset time on in-hospital mortality of patients with AAAD of different gender.

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Aim: To explore whether general self-efficacy can mediate the relationship between social support and quality of life in patients after surgical aortic valve replacement.

Design: A cross-sectional design.

Methods: The final analysis included 283 patients who underwent surgical aortic valve replacement from May 2021 to September 2021.

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Background: Studies suggest that high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV) can prevent reintubation in critically ill patients with a low risk of extubation failure. However, the safety and effectiveness in patients at high risk of extubation failure are still debated. Therefore, we conducted a systematic review and meta-analysis to compare the efficacies of HFNC and NIV in high-risk patients.

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Background: Postoperative delirium (POD) is an acute brain dysfunction that is frequently observed in patients undergoing cardiac surgery. Increasing evidence indicates POD is related to higher mortality among cardiac surgical patients, but the results remain controversial. Moreover, a quantitative evaluation of the influence of POD on hospital days, intensive care unit (ICU) time, and mechanical ventilation (MV) time has not been performed.

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Background: The benefits of breast milk oral care in mechanically ventilated preterm infants remain controversial. This study aimed to systematically review the evidence on the benefits of breast milk oral care in mechanically ventilated preterm infants.

Methods: The randomized controlled trials of breast milk oral care for mechanically ventilated preterm infants were searched in EMBASE, PubMed, Cochrane Library, Web of Science, WANFANG Date and China National Knowledge Infrastructure databases.

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: Accumulated studies have revealed that heart rates are associated with all-cause mortality in cardiac surgery patients, but the results remain controversial. This meta-analysis aimed to evaluate the predictive value of increased perioperative heart rate for all-cause mortality after cardiac surgery. : We searched PubMed, Embase, Web of Science, and Cumulative Index of Nursing and Allied Health Literature (CINAHL) databases for studies from inception to October 11, 2021.

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Aim: This study aimed to determine whether family-centred care (FCC) intervention reduces the ICU delirium prevalence.

Design: A systematic review and meta-analysis.

Methods: The databases, including PubMed, Cochrane Central Register of Controlled Trials, Web of Science, CINAHL Complete, China National Knowledge Infrastructure (CNKI), China Biology Medicine disc (CBMdisc), WANFANG Data and VIP Information, were systematically searched up to 30 November 2021.

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Previous studies have demonstrated that admission hyperglycemia is a predictor of mortality and poor prognosis in patients with cardiovascular diseases, such as acute myocardial infarction. However, the prognostic value of admission hyperglycemia in patients with acute type A aortic dissection (AAAD) has never been explored. To clarify the association between hyperglycemia and in-hospital outcomes, we retrospectively analyzed 734 patients with AAAD.

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Background: Blood glucose variability is associated with poor prognosis after cardiac surgery, but the relationship between glucose variability and postoperative delirium in patients with acute aortic dissection is unclear. The study aims to investigate the association of blood glucose variability with postoperative delirium in acute aortic dissection patients.

Methods: We prospectively analyzed 257 patients including 103 patients with delirium.

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Background: Abnormal body mass index (BMI) has been related to a higher risk of adverse outcomes in patients undergoing cardiac surgery. However, the effects of BMI in patients with acute type A aortic dissection (AAAD) on postoperative outcomes remain unclear. This study aimed to explore the relationships between BMI and in-hospital major adverse outcomes (MAO) in AAAD patients.

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Objective: Gestational diabetes mellitus (GDM) is induced by multiple factors, and the microRNAs (miRNAs) are well-known to be implicated in GDM progression. We aimed to explore the functional mechanisms of miR-222 in the inflammatory response in GDM by mediating C-X-C chemokine receptor type 4 (CXCR4) and NLRP3 inflammasomes.

Methods: GDM models were established by intraperitoneal injection of streptozocin, and the levels of miR-222 and CXCR4 in GDM patients' placenta tissues as well as GDM mice' placenta and pancreatic tissues were determined.

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Background: The prognostic nutritional index (PNI) has recently been reported to associate with the surgical prognosis of patients with some cardiovascular diseases. However, the prognosis significance of the preoperative PNI in patients with acute type A aortic dissection (AAAD) remains unclear.

Objectives: The present study aimed to explore the relationship between PNI and postoperative in-hospital mortality in patients with AAAD.

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Article Synopsis
  • * Out of 280 patients, the incidence of POD was found to be 37.86%, influenced by factors such as high APACHE-II scores, hypoxemia, and the use of multiple analgesics/sedatives, while non-manual work was identified as a protective factor.
  • * The findings suggest that certain clinical and demographic factors significantly correlate with the risk of POD, emphasizing the need for careful monitoring and potential interventions in at-risk patients post-surgery.
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