Publications by authors named "Lingyi Wan"
Objective: Polycystic ovarian syndrome (PCOS) is a common disorder that leads to infertility in reproductive-aged females. HOTAIR is highly expressed in various gynecological diseases and is associated with a poor prognosis. We aimed to explore the role of HOTAIR in PCOS.
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- Wuzi Yanzong pill (WZYZP) is a traditional Chinese medicine used since the Tang dynasty for improving kidney health and treating male infertility.
- This study aimed to investigate the protective effects of WZYZP on spermatogenesis disorders through both animal and cell studies, measuring outcomes like sperm count, motility, and hormone levels.
- Results indicated that WZYZP significantly improved sperm parameters, reduced testicular cell apoptosis, and influenced key signaling pathways related to cell growth and survival.
The crisis of male infertility is an issue of human reproductive health worldwide. The Wuzi Yanzong pill (WZYZP) is a traditional Chinese medicine prescription that shows efficacy in kidney reinforcement and essence benefit to ameliorate male reproductive dysfunctions. However, the pharmacological mechanisms of the WZYZP on male infertility have not been investigated and clarified clearly.
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