Lactylation Modification as a Promoter of Bladder Cancer: Insights from Multi-Omics Analysis.

Bladder cancer (BLAC) is a malignant tumor with high morbidity and mortality. The establishment of a prognostic model for BLAC is of great significance for clinical prognosis prediction and treatment guidance. Lactylation modification is a newly discovered post-transcriptional modification of proteins, which is closely related to the occurrence and development of tumors.

Single-Cell RNA-Sequencing: Opening New Horizons for Breast Cancer Research.

Breast cancer is the most prevalent malignant tumor among women with high heterogeneity. Traditional techniques frequently struggle to comprehensively capture the intricacy and variety of cellular states and interactions within breast cancer. As global precision medicine rapidly advances, single-cell RNA sequencing (scRNA-seq) has become a highly effective technique, revolutionizing breast cancer research by offering unprecedented insights into the cellular heterogeneity and complexity of breast cancer.

Artificial intelligence: illuminating the depths of the tumor microenvironment.

Artificial intelligence (AI) can acquire characteristics that are not yet known to humans through extensive learning, enabling to handle large amounts of pathology image data. Divided into machine learning and deep learning, AI has the advantage of handling large amounts of data and processing image analysis, consequently it also has a great potential in accurately assessing tumour microenvironment (TME) models. With the complex composition of the TME, in-depth study of TME contributes to new ideas for treatment, assessment of patient response to postoperative therapy and prognostic prediction.

Experimental investigation on electromagnetic induction thermal desorption for remediation of petroleum hydrocarbons contaminated soil.

A novel electromagnetic induction low temperature thermal desorption treatment (EMI LTTD) for petroleum hydrocarbons contaminated soil was introduced in this work. The removal rate of total petroleum hydrocarbons (TPH) under various factors, the morphology changes of soils as well as removal mechanism were investigated. Results suggested that increasing the heating temperature significantly increased the removal rate of TPH.

Study on landscape evaluation and optimization strategy of Central Park in Qingkou Town.

This article mainly discusses the evaluation and optimization of the green space utilization value of comprehensive parks used by people in dense urban areas based on the desire for green and healthy living in the postepidemic era. As a qualitative study of urban parks, this study builds an evaluation system based on the American landscape performance series and combines it with comprehensive indicators of China's urban parks, including environmental performance (such as park planning, infrastructure, trails, and vegetation), health performance (such as cultural education, park activities, and transportation accessibility) economic performance (such as tourist consumption and stimulating the development of surrounding construction) and three other aspects: conducting a site evaluation; evaluating observed behavior, interviews and questionnaires; and performing the analytic hierarchy process-coefficient of variation weight comprehensive evaluation analysis. Additionally, the park comprehensive index, land use index, traffic convenience, park vitality index and other dynamic changes are analyzed over time.