Seasonal succession of endophyte and the association with active ingredients in .

Unlabelled: The endophyte is closely related to medicinal plant growth and development, stress resistance, and active ingredients' accumulation. However, a seasonal succession of endophytes and the association with active ingredients is still unclear. In this study, we used high-throughput sequencing methods to compare the endophyte diversity of under different seasons and analyze the association between endophytes and five active ingredients.

The fate of antibiotics and antibiotic resistance genes in Large-Scale chicken farm Environments: Preliminary view of the performance of National veterinary Antimicrobial use reduction Action in Guangdong, China.

In 2018, China implemented the Veterinary Antimicrobial Use Reduction Action to curb the rapid development of antibiotic resistance (AR). However, the AR-related pollutions in animal farms after the reduction policy has been poorly investigated. Here, we performed a comprehensive investigation combining UPLC-MS/MS, metagenomic, and bacterial genomic analyses in eight representative large-scale chicken farms in Guangdong, China.

Research Note: Synergistic effect of isopropoxy benzene guanidine and colistin against mcr-1-positive Escherichia coli in vitro and in duck intestine infection models.

Colistin (CST) is considered as "agent of last resort" against gram-negative bacteria as feed additive. Its clinical effectiveness has reduced since the emergence of mcr-1 gene in ducks. Isopropoxy benzene guanidine (IBG), a new guanidine derivative, showed positive effects on improving animal weights and alleviating intestinal pathogens, therefore, the objective of this study was to evaluate the effect of this compound supplement with CST in ducks and explore the possibilities in feed additive.

Fast Adiabatic Mode Evolution Assisted 2 × 2 Broadband 3 dB Coupler Using Silicon-on-Insulator Fishbone-like Grating Waveguides.

We report a novel 2 × 2 broadband 3 dB coupler based on fast adiabatic mode evolution with a compact footprint and large bandwidth. The working principle of the coupler is based on the rapid adiabatic evolution of local eigenmodes of fishbone-like grating waveguides. Different from a traditional adiabatic coupling method realized by the slow change of the cross-section size of a strip waveguide, a fishbone waveguide allows faster adiabatic transition with proper structure and segment designs.

Single-nucleus transcriptomic mapping of blast-induced traumatic brain injury in mice hippocampus.

As a significant type of traumatic brain injury (TBI), blast-induced traumatic brain injury (bTBI) frequently results in severe neurological and psychological impairments. Due to its unique mechanistic and clinical features, bTBI presents diagnostic and therapeutic challenges compared to other TBI forms. The hippocampus, an important site for secondary injury of bTBI, serves as a key niche for neural regeneration and repair post-injury, and is closely associated with the neurological outcomes of bTBI patients.

Single-nucleus transcriptomic mapping uncovers targets for traumatic brain injury.

The subventricular zone (SVZ) is a neurogenic niche that contributes to homeostasis and repair after brain injury. However, the effects of mild traumatic brain injury (mTBI) on the divergence of the regulatory DNA landscape within the SVZ and its link to functional alterations remain unexplored. In this study, we mapped the transcriptome atlas of murine SVZ and its responses to mTBI at the single-cell level.

Suppressing grating lobes of large-aperture optical phased array with circular array design.

An optical phased array (OPA), especially a two-dimensional (2D) OPA, suffers from the trade-off among steering range, beam width, and the number of antennas. Aperiodic 2D array designs currently aimed to reduce the number of antennas and reduce grating lobes within a wide range fall short when an aperture approaches millimeter size. A circular OPA design is proposed to address this issue.

One health genomic insights into the host-specific evolution and cross-host transmission of Staphylococcus aureus in animal farm environments, food of animal origin, and humans.

Objectives: Staphylococcus aureus is an opportunistic pathogen that is considered a high priority for research. However, comparative studies of S. aureus strains from different environments and hosts are still lacking.

Si Photonics FMCW LiDAR Chip with Solid-State Beam Steering by Interleaved Coaxial Optical Phased Array.

LiDAR has attracted increasing attention because of its strong anti-interference ability and high resolution. Traditional LiDAR systems rely on discrete components and face the challenges of high cost, large volume, and complex construction. Photonic integration technology can solve these problems and achieve high integration, compact dimension, and low-cost on-chip LiDAR solutions.

Molecular epidemiology and transmission of rmtB-positive Escherichia coli among ducks and environment.

This study aimed to investigate the transmission and molecular epidemiological characteristics of the rmtB gene in Escherichia coli (E. coli) strains isolated from duck farms in Guangdong Province of China from 2018 to 2021. A total of 164 (19.

Intermittent fasting ameliorates neuronal ferroptosis and cognitive impairment in mice after traumatic brain injury.

Ferroptosis, a newly characterized form of programmed cell death that results from lipid peroxidation and mitochondrial dysfunction, has been demonstrated to be involved in the pathogenesis of traumatic brain injury (TBI). Scientific evidence has shown that intermittent fasting (IF) reduces both the lipid peroxidation and the mitochondrial dysfunction, raising the question of whether IF affects the ferroptosis induced by TBI. Here, based on an established TBI animal model, we examine the effects of IF on the activation of ferroptosis pathway as well as related outcomes.

Effective half-wavelength pitch optical phased array design for aliasing-free 2D beam steering.

We present a method to design an optical phased array (OPA) simultaneously realizing both narrow beam width and aliasing-free 2D beam steering without the need to arrange the antennas at actual half-wavelength pitch. The method realizes an effective half-wavelength pitch in one direction formed by location projection of the antennas. The distances between the antennas in the other direction can be sufficiently large to form an effective large aperture realizing narrow beam width without needing a long grating.

Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury.

Explosive blast-related traumatic brain injuries (bTBI) are common in war zones and urban terrorist attacks. These bTBIs often result in complex neuropathologic damage and neurologic complications. However, there is still a lack of specific strategies for diagnosing and/or treating bTBIs.

Two-dimensional single-lobe Si photonic optical phased array with minimal antennas using a non-uniform large spacing array design.

We report a two-dimensional Si photonic optical phased array (OPA) optimized for a large optical aperture with a minimal number of antennas while maintaining single-lobe far field. The OPA chip has an optical aperture of ∼200µ by 150 µm comprising a 9×9 antenna array. The two-dimensional spacings between these antennas are much larger than the wavelength and are highly non-uniform optimized by the genetic deep learning algorithm.

Compact 2D serpentine optical phased array.

We present a two-dimensional (2D) Si photonics optical phased array (OPA) using a serpentine design which eliminates the long directional couplers used in many 2D OPA designs. It significantly reduces the distance between the antenna benefitting far-field sidelobe reduction while maintaining high optical power use efficiency.

Impact of third-order dispersion and three-photon absorption on mid-infrared time magnification via four-wave mixing in SiGe waveguides.

We investigate the influence of third-order dispersion of dispersive elements, three-photon absorption and free-carrier effects on mid-infrared time magnification via four-wave mixing (FWM) in ${{\rm Si}_{0.8}}{{\rm Ge}_{0.2}}$SiGe waveguides.

Defect States Emerging from a Non-Hermitian Flatband of Photonic Zero Modes.

We show the existence of a flatband consisting of photonic zero modes in a gain and loss modulated lattice system as a result of the underlying non-Hermitian particle-hole symmetry. This general finding explains the previous observation in parity-time symmetric systems where non-Hermitian particle-hole symmetry is hidden. We further discuss the defect states in these systems, whose emergence can be viewed as an unconventional alignment of a pseudospin under the influence of a complex-valued pseudomagnetic field.

Broadband self-collimating phenomenon in a low-loss hybrid plasmonic photonic crystal.

A 2D planar self-collimating photonic crystal, based on a dielectric square lattice and a hexagonal lattice, is proposed. We demonstrate that the proposed structure can support the propagation of a hybrid surface plasmon polarition (SPP) mode with a loss of -0.017  dB/μm, and the mode size is only 0.

Nanoslit-microcavity-based narrow band absorber for sensing applications.

We propose an ultranarrow bandwidth perfect infrared absorber consisting of a metal periodic structured surface with nanoslits, a spacer dielectric, and a metal back plate. Its bandwidth and aborption are respectively about 8 nm and 95%. The thickness of the nanobars and the spacer, and the width of the nanoslits are primary factors determining the absorption performance.